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Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of

Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>

Background: Elderly individuals with chronic conditions or acute illnesses are major drivers of hospitalization, with frail patients frequently utilizing emergency department (ED) services. To ease this burden, many countries offer home-based medical services. In Region Halland, Sweden, a mobile team intervention in municipal home care (MHC) was introduced to support frail elderly patients. This s

Course literature is an important part of your studies. You can access the books you need by borrowing them from the library, buying them new or used, or using online resources. Planning ahead can help you save both time and money. Reading listsUniversity programmes and courses often have long reading lists. These are usually available at the start of the course and include the books you are expec

https://www.lunduniversity.lu.se/current-students/student-services-and-support/literature-and-libraries/course-literature - 2026-06-17

For help with everyday questions and issues as a student Welcome all international students!All incoming international students are welcome to contact the International Desk for help with practical matters. Anything from where to buy a bike, how to find your department or how to get involved in student life is welcome.The International Desk can also provide you with a manually signed transcript of

https://www.lunduniversity.lu.se/current-students/student-services-and-support/international-desk - 2026-06-17

Lund University is primarily based in the city of Lund, close to Malmö, Sweden's third-largest city, in the southern part of the country. Malmö and Helsingborg are its other campus cities. The region is also very close to Copenhagen, Denmark. The main campus buildings are centrally located in Lund, just a 5- to 10-minute walk from the railway station.Travelling to Lund from abroadThere are several

https://www.lunduniversity.lu.se/about-university/visit-lund-university - 2026-06-17