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In this study a method for small scale purification of the protein RAGE (receptor for advanced glycation endproducts) was developed and soluble RAGE was purified from bovine and mice tissue. In healthy animals RAGE is expressed in measurable levels only in lungs and therefore lungs have been used. The tissue was homogenized and thereafter RAGE was purified using Concanavaline A (Con A)-Sepharose,
Background and Aims: In primary sclerosing cholangitis (PSC), the risk for gallbladder malignancy is increased. Surveillance imaging is used for early diagnosis. The study aims to assess the reliability of ultrasound and magnetic resonance imaging (MRI) for the detection of gallbladder polyps in people with PSC and to define a polyp size as a cut-off at which cholecystectomy is indicated due to th
Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) has emerged as an important imaging technique for prostate cancer. The use of PSMA PET/CT is rapidly increasing, while the number of nuclear medicine physicians and radiologists to interpret these scans is limited. Additionally, there is variability in interpretation among readers. Artificial intell
This work presents the development and evaluation of a Direct Membrane Filtration (DMF) concept for municipal wastewater treatment, integrating microsieving, microfiltration/ultrafiltration (MF/UF), and downstream polishing with activated carbon. DMF enables the efficient separation of particulate organic matter directly from raw wastewater, producing a retentate suitable for enhanced biogas produ
Background Introducing services for manufacturing companies can lead to improving customer satisfaction and new revenue streams as well as creating a more sustainable business. However, the current understanding of how this can be done in practice is limited. Purpose This master’s thesis investigates how a manufacturing company can generate sustainable value through the introduction of new repair
This thesis is devoted to the analysis of the I-V properties of axial InP pn-junction nanowires made for solar cell application. A novel method has been used to measure the I-V characteristics very accurately and reproducibly, using scanning tunneling microscopy (STM). The STM is used to first image the nanowires from top and then form a low resistive point contact between the STM tip and an indiv
In neuroblastoma (NB) patients, minimal residual disease (MRD) can be detected by real-time quantitative PCR (qPCR) using NB-specific target genes, such as PHOX2B and TH. However, it is unknown whether the mRNA levels of these targets vary either during treatment or at relapse. If marker genes are not stably expressed, estimation of MRD levels in bone marrow (BM) or peripheral blood will be hamper
Employing a large number of antennas at the base station, massive MIMO significantly improves spectral efficiency and transmit power efficiency. On the other hand, massive MIMO also introduces unprecedented implementation challenges, especially in terms of processing and storage of large-size channel state information (CSI) matrices. Since on-chip memory is generally very expensive and has limited
This study explored the ability of blind and sighted listeners to detect reflections, "echoes", of burst trains or continuous noise. Echo detection was compared by presenting 5 ms bursts, rates from 1 to 64 bursts, with a continuous white noise, all during 500 ms. Sounds were recorded in an ordinary room through an artificial binaural head, the loudspeaker 1 m behind it. The reflecting object was
Background: Serial transverse enteroplasty facilitates weaning from parenteral support in selected patients with short bowel syndrome, although repeated procedure is frequently required. Our aim was to evaluate the outcome of a series of patients after serial transverse enteroplasty and define predictors of repeated serial transverse enteroplasty and weaning off parenteral support. Methods: All ch
Self-other similarity judgment asymmetry refers to the tendency of people to judge others to be more similar to themselves than they judge themselves to be similar to others. This effect can be explained with both a cognitive model (Tversky, 1977) and a motivational explanation (Codol, 1987). Recent research has provided initial evidence for the core assumption of the motivational explanation and
