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Albumin (HSA) is the dominating protein in human plasma. Many bacterial species, especially streptococci, express surface proteins that bind HSA with high specificity and affinity, but the biological consequences of these protein-protein interactions are poorly understood. Group G streptococci (GGS), carrying the HSA-binding protein G, colonize the skin and the mucosa of the upper respiratory trac
BACKGROUND: Lung transplantation (LTx) is established as a life-saving treatment in end-stage lung disease. However, long-term survival is hampered by the development of chronic rejection, almost synonymous with bronchiolitis obliterans syndrome (BOS). The rejection is characterized by deposition of extracellular matrix in small airways. Fibroblasts/myofibroblasts are the main producers of extrace
In adults, the size of the left atria (LA) has important prognostic information. In obese adults, adolescents and children enlargement of LA have been observed. This has not been investigated on a population-based level in young children. We therefore assessed if total body fat mass (TBF), abdominal fat, and body fat distribution were related to LA diameter. Cross-sectional study of 244 children (
Social capital research has consistently shown positive associations between generalised trust and health outcomes over 2 decades. Longitudinal studies attempting to test causal relationships further support the theory that trust is an independent predictor of health. However, as the reverse causality hypothesis has yet to be empirically tested, a knowledge gap remains. The aim of this study, ther
Popular Abstract in English Proteins are a big biological molecules that help cells to function. Proteins play important roles in all vital processes of the living cell, transporting molecules, speeding up chemical reactions, supporting structure of other proteins and the cell, helping the cell to move. Various disease-causing agents (e.g. bacteria and viruses) are constant threat to us. It is thMost drugs act on biomacromolecules. The Cost of developing new drugs is very high. A method to accurately predict binding affinities would be very useful. We have studied molecular mechanics with generalised Born and surface--area solvation (MM/GBSA) and alchemical free energy perturbation methods (FEP) for use in calculations of ligand binding energies. For the MM/GBSA method we have tested: Ca
The aim of this article is to explore the social meaning and ordinary activities surrounding informal transactions in order to better understand the social context forming the premises and informing the meaning of corruption in Uzbekistan. A theoretically founded hypothesis is that informal transactions in Uzbek society reflect different cultural meanings than in the Western world. If this is true
BACKGROUND: HIV and other sexually transmitted infections are a growing problem in the military personnel of Africa, and information about this problem in Guinea-Bissau is lacking. The aims of this study were to determine the prevalence and trends of the HIV epidemics in the military forces of Guinea Bissau and to explore possible risk factors for HIV infection. METHODOLOGY: Repeated cross-sectio
The area of direct taxation is, as a consequence of the limited harmonisation within the EU, an area surrounded by several interests that have appeared to be hard to unite. On one hand the EU Member States have the competence in the area of direct taxation to legislate in conformity with their own political considerations. On the other hand the EU law demands conformity with the freedoms regulated
Economic sanctions are defined as the exercise of pressure by one state to produce a change in the political behaviour of another state. Traditional economic sanctions are directed at the entire population of a state whilst targeted sanctions are directed at a state’s individuals. This thesis discusses the application of economic sanctions against Iran by the UN, the EU and the United States. Econ
With an increasing amount of literature on the convergence of archives and libraries as a point of departure, this thesis examines how archives and libraries respectively assign metadata to informational resources with queer content. Thereby, the thesis contribute to a theoretical convergence between the two institutions. A mixed method approach with quantitative and qualitative methods was chos
I föreliggande psykologexamensuppsats kombinerades kvalitativa och kvantitativa metoder i syfte att explorativt undersöka innehållet i pedagogers samtalsgrupper samt för att utforska samtalsledarens roll. Studien utformades i samråd med utbildningsförvaltningen i den studerade kommunen. Åtta samtalsgrupper deltog i en observationsundersökning. Ett strukturerat observationsschema, IPA, användes förIn the presented Master’s Thesis qualitative and quantitative methods were combined in order to, with an explorative approach, examine the content of the Teacher Learning Communities (TLC) and to examine the role of the facilitator. The study was developed in agreement with the Department of Education in the participating municipality. Eight TLCs were observed. A structured observation chart, IPA,
Background: Previous epidemiologic studies found inconsistent results for the association between red meat intake, nitrosamines [NDMA: N-nitrosodimethylamine, and ENOC (endogenous nitroso compounds)], and the risk of bladder cancer. We investigated the association between red meat consumption, dietary nitrosamines, and heme iron and the risk of bladder cancer among participants of the European Pro
Mental health problems among adolescents have become a major public health issue, and it is therefore important to increase knowledge on the contextual determinants of adolescent mental health. One such determinant is the socioeconomic structure of the neighbourhood. The present study has two central objectives, (i) to examine if neighbourhood socioeconomic deprivation is associated to individual
