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Evaluation of the creatinine-based chronic kidney disease in children (under 25 years) equation in healthy children and adolescents

Background: The Chronic Kidney Disease in children (CKiD) equation to estimate glomerular filtration rate eGFR = k × Ht / SCr (Ht = height in cm, SCr = serum creatinine in mg/dL), with fixed k = 0.413, has recently been optimized by introducing age/sex dependent k-values valid for young children up to young adults (the CKiD Under 25 years (CKiDU25) equation). Although the CKiD equation was designe

Occupational exposure to particles and biomarkers of cardiovascular disease—during work and after vacation

Objective: Ambient particle matter is a risk factor for cardiovascular disease (CVD). However, little is known about associations between particles in occupational settings and risk of CVD. We investigated associations between occupational dust exposure and biomarkers of CVD, and potential recovery effects after vacation. Methods: Personal dust exposure measurements (respirable silica, respirable

The Influence of Level of Education on Instrumental Activities of Daily Living in Patients with Alzheimer’s Disease.

Background: According to the “brain-reserve hypothesis” in Alzheimer’s disease (AD), patients with more years of education are expected to have higher cognitive status during adulthood. Hence, they might have a relatively larger burden of AD pathology and a more advanced level of the disease when dementia is clinically evident. Higher educated people would also be expected to perform better on sta

Fabrication of Single-Crystalline InSb-on-Insulator by Rapid Melt Growth

InSb has the smallest bandgap and highest electron mobility among III-V semiconductors and is widely used for photodetectors and high-frequency electronic applications. Integration of InSb directly on Si would drastically reduce the fabrication cost and enable new applications, however, it is very challenging due to its 19% lattice mismatch with Si. Herein, the integration of single-crystalline In

Nationwide paediatric cohort study of a protective association between allergy and complicated appendicitis

BACKGROUND: In a nationwide cohort the potentially protective association between allergy and complicated appendicitis was analysed, and the influence of seasonal antigens, antihistamine treatment, and timing of allergy onset assessed.METHODS: Some 1 112 571 children born between 2000 and 2010 were followed from birth until the end of 2014. A cross-sectional analysis of appendicitis cases, with co

Continuous gas-phase synthesis of core–shell nanoparticles via surface segregation

Synthesis methods of highly functional core@shell nanoparticles with high throughput and high purity are in great demand for applications, including catalysis and optoelectronics. Traditionally chemical synthesis has been widely explored, but recently, gas-phase methods have attracted attention since such methods can provide a more flexible choice of materials and altogether avoid solvents. Here,

Vapor-solid-solid growth dynamics in GaAs nanowires

Semiconductor nanowires are promising material systems for coming-of-age nanotechnology. The usage of the vapor-solid-solid (VSS) route, where the catalyst used for promoting axial growth of nanowires is a solid, offers certain advantages compared to the common vapor-liquid-solid (VLS) route (using a liquid catalyst). The VSS growth of group-IV elemental nanowires has been investigated by other gr

Influence of contacts and applied voltage on a structure of a single GaN nanowire

Semiconductor nanowires (NWs) have a broad range of applications for nano-and optoelectronics. The strain field of gallium nitride (GaN) NWs could be significantly changed when contacts are applied to them to form a final device, especially considering the piezoelectric properties of GaN. Investigation of influence of the metallic contacts on the structure of the NWs is of high importance for thei

Preventing Cardiovascular Disease. Complementary precision medicine.

AbstractBackground: Non-communicable diseases are the number one killer worldwide and the leading one,cardiovascular disease (CVD), is responsible for more than 30% of all deaths. CVD is a progressive disease whichalso makes it economical, easy and effective to prevent. There are many stages of CVD that ultimately can lead tocoronary atherosclerosis, measurable as coronary artery calcification (CA

Stroboscopic operando spectroscopy of the dynamics in heterogeneous catalysis by event-averaging

Heterogeneous catalyst surfaces are dynamic entities that respond rapidly to changes in their local gas environment, and the dynamics of the response is a decisive factor for the catalysts’ action and activity. Few probes are able to map catalyst structure and local gas environment simultaneously under reaction conditions at the timescales of the dynamic changes. Here we use the CO oxidation react

Noise-free on-demand atomic frequency comb quantum memory

We present an extension of the atomic frequency comb protocol that utilizes the Stark effect to perform noise-free, on-demand, control. An experimental realization of this protocol was implemented in the Pr3+:Y2SiO5 solid-state system, and a recall efficiency of 38% for a 0.8 μs storage time was achieved. Experiments were performed with both bright pulses as well as weak-coherent states, the latte

ERS/EAACI statement on adherence to international adult asthma guidelines

Guidelines aim to standardise and optimise asthma diagnosis and management. Nevertheless, adherence to guidelines is suboptimal and may vary across different healthcare professional (HCP) groups. Further to these concerns, this European Respiratory Society (ERS)/European Academy of Allergy and Clinical Immunology (EAACI) statement aims to: 1) evaluate the understanding of and adherence to internat

Self-Perceived Life Satisfaction during the First Wave of the COVID-19 Pandemic in Sweden : A Cross-Sectional Study

Currently, there is limited knowledge on how the Swedish strategy with more lenient public health restrictions during the COVID-19 pandemic has influenced people's life satisfaction. Here, we investigated self-reported life satisfaction during the first wave of the pandemic in Sweden, and perceived changes in life satisfaction in relation to various sociodemographic factors. A total of 1082 people

What if something happens tonight? : A qualitative study of primary care physicians' perspectives on an alternative to hospital admittance

BACKGROUND: Due to demographic changes, hospital emergency departments in many countries are overcrowded. Internationally, several primary healthcare models have been introduced as alternatives to hospitalisation. In Norway, municipal acute wards (MAWs) have been implemented as primary care wards that provide observation and medical treatment for 24 h. The intention is to replace hospitalisation f

Major depressive disorders in young immigrants : A cohort study from primary healthcare settings in Sweden

Aims: Previous studies on major depressive disorder (MDD) among immigrants have reported mixed results. Using data from primary healthcare settings in Sweden, we compared the incidence of MDD among first- and second-generation immigrants aged 15–39 years with natives. Methods: This was a retrospective nationwide open cohort study. Eligible individuals were born 1965–1983, aged 15–39 years at basel

Thermodynamic modeling framework for prediction of tool wear and tool protection phenomena in machining

Chemical, oxidational and diffusional interactions between the tool, chip and cutting environment are known tool wear mechanisms in machining. However, the interaction between tool, coating, workpiece, coolant and atmospheric oxygen can, under favorable conditions, lead to formation of reaction products that retard tool wear. A method with the ability to predict theses interactions, would therefor

Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure

Background: Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2, ASXL1, and JAK2) in asymptomatic individuals, is associated with cardiovascular events, including recurrent heart failure (HF). Objectives: This study sought to evaluate whether CHIP is associated with incident HF. Methods: CHI

Newer Forms of Contract-Based Dispute Resolution : An examination of efficiency-driven procedures in light of traditional adversarial procedures

This thesis takes an interest in newer forms of contract-based dispute resolution used in commercial disputes. Public civil trial and arbitration has for a long time been the procedure of choice for disputing commercial parties. Arbitration is still by far the most established and used procedure when it comes to private dispute resolution. However, for some decades, newer forms of private procedur

Reducing search times and entropy in hospital emergency departments with real-time location systems

Although the consequences of hospital ED crowding have been studied extensively, the causes of crowding are still not well understood. Throughput factors in ED crowding models are difficult to study in a controlled fashion in a dynamic environment where healthcare demand changes rapidly, and physical and human resources suddenly become limited. Opportunities for automated, simultaneous, and low-co