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Early-life exposure to perfluoroalkyl substances and serum antibody concentrations towards common childhood vaccines in 18-month-old children in the Odense Child Cohort
Exposure to per- and polyfluoroalkyl substances (PFAS) has been associated with reduced antibody response to childhood vaccinations. Previous studies have mostly focused on antibodies against diphtheria or tetanus, while fewer studies have assessed antibodies toward attenuated viruses, such as measles, mumps or rubella (MMR). Therefore, we set out to determine associations between prenatal and ear
Genome-Wide Association Studies of 3 Distinct Recovery Phenotypes in Mild Ischemic Stroke
BACKGROUND AND OBJECTIVES: Stroke genetic research has made substantial progress in the past decade. Its recovery application, however, remains behind, in part due to its reliance on the modified Rankin Scale (mRS) score as a measure of poststroke outcome. The mRS does not map well to biological processes because numerous psychosocial factors drive much of what the mRS captures. Second, the mRS co
Risk assessment of SWEN21 a suggested new dive table for the Swedish armed forces : bubble grades by ultrasonography
Introduction: To develop the diving capacity in the Swedish armed forces the current air decompression tables are under revision. A new decompression table named SWEN21 has been created to have a projected risk level of 1% for decompression sickness (DCS) at the no stop limits. The aim of this study was to evaluate the safety of SWEN21 through the measurement of venous gas emboli (VGE) in a dive s
Beyond Average : a-Particle Distribution and Dose Heterogeneity in Bone Metastatic Prostate Cancer
a-particle emitters are emerging as a potent modality for disseminated cancer therapy because of their high linear energy transfer and localized absorbed dose profile. Despite great interest and pharmaceutical development, there is scant information on the distribution of these agents at the scale of the a-particle pathlength. We sought to determine the distribution of clinically approved [223Ra]R
Rare-variant collapsing and bioinformatic analyses for different types of cardiac arrhythmias in the UK Biobank reveal novel susceptibility loci and candidate amyloid-forming proteins
Background: Cardiac arrhythmias are a common health problem. Both common and rare genetic risk factors exist for cardiac arrhythmias. Cardiac amyloidosis is a rare disease that may manifest various arrhythmias. Few large-scale whole exome sequencing studies elucidating the contribution of rare variations to arrhythmias have been published. Objective: To access gene collapsing analysis of rare vari
Monkeypox virus-associated meningoencephalitis diagnosed by detection of intrathecal antibody production
Background: In the 2022 mpox-outbreak most patients presented with mild symptoms. Central nervous system (CNS) involvement has previously been described as a rare and severe complication of mpox; however, diagnostic findings in cerebrospinal fluid (CSF) analysis and neuroimaging studies have only been reported in one case previously. Case presentation: We report a previously healthy 37-year-old ma
Blood cadmium is associated with increased fracture risk in never-smokers - results from a case-control study using data from the Malmö Diet and Cancer cohort
Background: Several studies have shown associations between cadmium (Cd) exposure and an increased risk of fractures. However, the size of the risk is still unclear and proper adjustment for smoking is a challenge. The aim of this study was to quantify the association between dietary cadmium measured in blood and fracture risk in the general Swedish population through a large population-based case
Tackling Brexit: An idea analysis on the similarities of the 2016 Brexit debate and the debate on foreign players in the Premier League
Late diagnosis of HIV persists in Sweden : Differing social determinants among migrant and non-migrant people with HIV
Objective: To examine temporal changes in late diagnosis of HIV (LD) among migrant and non-migrant people with HIV in Sweden 2003–2023 and to assess demographic and socioeconomic risk factors for LD in these two populations. Methods: People with HIV diagnosed with HIV-1 in Sweden 2003–2023 were included (n = 6278). LD was defined as a first CD4+ T-cell count <350 cells/μL or an AIDS-defining event
Determinants and prognostic value of blood pressure trajectories during graded exercise
PURPOSE: The systolic blood pressure (SBP) response to exercise reflects cardiovascular health, with both exaggerated and blunted responses linked to adverse outcomes. Prior studies relied typically on peak SBP or two-point slopes for evaluation. We aimed to identify distinct SBP responses from full times-series recorded during maximal, graded exercise and assess their clinical determinants and pr
Support, Monitoring, and Reminder Technology for Mild Dementia (SMART4MD) for People With Mild Cognitive Impairment and Their Informal Caregivers: Cost-Effectiveness Analysis
Background:Support, Monitoring, and Reminder Technology for Mild Dementia (SMART4MD), a customized tablet app, was developed to improve or maintain the quality of life of people with mild cognitive impairment (MCI) and their informal caregivers.Objective:This study conducts an 18-month economic evaluation of the SMART4MD app, in addition to standard care, compared with standard care alone in Swede
Post-Acquisition Integration: The Effect of Vision Communication on the Development of an Integration Capability and Alleviation of Task Uncertainties
Methodology: The method used is a single case study in a high tech company in Sweden, leader in network camera market. This work is a qualitative research, in which an inductive method and deductive analysis has been applied. Grounded-theory techniques have been used; eight semi-structured interviews were conducted-carefully and objectively selected following purposive sampling. Theoretical persp
Distribution patterns of epiphytic reed-associated macroinvertebrate communities across European shallow lakes
So far, research on plant-associated macroinvertebrates, even if conducted on a large number of water bodies, has mostly focused on a relatively small area, permitting limited conclusions to be drawn regarding potentially broader geographic effects, including climate. Some recent studies have shown that the composition of epiphytic communities may differ considerably among climatic zones. To asses
Revealing vibronic coupling in chlorophyll c1 by polarization-controlled 2D electronic spectroscopy
Vibronic coupling between molecules has been recently discussed to play an important role in photosynthetic functions. Furthermore, this type of coupling between electronic states has been suggested to define photophysical properties of chlorophylls, a family of photosynthetic molecules. However, experimental investigation of vibronic coupling presents a major challenge. One subtle way to study vi
Can you feel the beat? How to define reference ranges for ambulatory heart rhythm monitoring
Optical : In situ monitoring during the synthesis of halide perovskite solar cells reveals formation kinetics and evolution of optoelectronic properties
The formation mechanism and the evolution of optoelectronic properties during annealing of chlorine-derived methylammonium lead iodide (MAPbI3-xClx) are investigated in detail combining in situ and ex situ optical and structural characterization. Using in situ optical reflectometry we are able to monitor the evolution of the MAPbI3-xClx phase as a function of time and processing temperature. The f
A focus group interview study of the experience of stress amongst school-aged children in Sweden
The study explored experiences of stress in children aged 10–12. An inductive qualitative design was used. Ten focus group interviews were conducted with Swedish schoolchildren (n = 42) aged 10–12. The interviews were audio-recorded, transcribed verbatim, and analyzed using qualitative content analysis. The study identified one theme—“Body and mind react”—and three subthemes: (1) Friendships matte
Relating Defect Luminescence and Nonradiative Charge Recombination in MAPbI3 Perovskite Films
Nonradiative losses in semiconductors are related to defects. At cryogenic temperatures, defect-related photoluminescence (PL) at energies lower than the band-edge PL is observed in methylammonium lead triiodide perovskite. We applied multispectral PL imaging to samples prepared by two different procedures and exhibiting 1 order of magnitude different PL quantum yield (PLQY). The high-PLQY sample
Aligning the good practice mask with the objectives of the European innovation partnership on active and healthy ageing
The reference sites of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) were renewed in 2019. The DG Santé good practice Mobile Airways Sentinel networK was reviewed to meet the objectives of the EIP on AHA. It included 1) Management of care process, 2) Blueprint of digital transformation, 3) EIP on AHA, innovation to market, 4) Community for monitoring and assessment
