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Method for the recovery of stabilized polyhydroxyalkanoates from biomass that has been used to treat organic waste

The invention is directed to a method of increasing the chemical and/or thermal stability of PHA in biomass where the biomass is contained within mixed liquor, and wherein the mixed liquor is treated by a combination of removing water from the mixed liquor and pH adjustment of the mixed liquor or maintenance of the pH of the mixed liquor within a selected pH range, and wherein the method includes

Polymeric material comprising ortho-positioned acidic groups

The present invention relates to a polymeric material comprising structural elements of the following general formula (I): wherein Ph1, Ph2 and Ph3 independently are phenylenes comprising acidic groups with or without a spacer or salts thereof; X1, X2, X3 and X4 independently are O, S, SO, SO2, or a direct bond and wherein X1 also may be H termination when Formula (I) relates to side chains of the

Prediction, Design and Determination of Protein Structures

Popular Abstract in English Life on earth has evolved countless forms, beautiful shapes and colors as well as astonishingly complex systems. Remarkably, all living creatures consist of cells, which themselves are build from the same basic set of molecules, most importantly nucleic acids (RNA and DNA), lipids and proteins. The latter are large macromolecules that fulfill a vast number of tasks; theThe three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. We used the Fold-and-Dock algorithm, which is part of the Rosetta macromolecular modeling suite, for de novo structure prediction of coiled-coil proteins. Members of this protein family

Challenges with risk and vulnerability analyses : Strategies for integration in risk and crisis management

Today risk analyses are commonly used by authorities at national, regional and municipal levels in their work to prevent and prepare for crises. The analyses provide information about types of incidents that can occur and the potential consequences of these events. In Sweden and Norway it is mandatory for local authorities to conduct risk and vulnerability analyses and use them as an input in thei

Air pollution is associated with primary health care visits for asthma in Sweden : A case-crossover design with a distributed lag non-linear model

Background: Air pollution can increase the symptoms of asthma and has an acute effect on the number of emergency room visits and hospital admissions because of asthma, but little is known about the effect of air pollution on the number of primary health care (PHC) visits for asthma. Objective: To investigate the association between air pollution and the number of PHC visits for asthma in Scania, s

MYBPC3 hypertrophic cardiomyopathy can be detected by using advanced ECG in children and young adults

Introduction The conventional ECG is commonly used to screen for hypertrophic cardiomyopathy (HCM), but up to 25% of adults and possibly larger percentages of children with HCM have no distinctive abnormalities on the conventional ECG, whereas 5 to 15% of healthy young athletes do. Recently, a 5-min resting advanced 12-lead ECG test ("A-ECG score") showed superiority to pooled criteria from the st

Vital capacity and COPD : The Swedish CArdioPulmonary bioImage Study (SCAPIS)

Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio of forced expiratory volume in 1 second (FEV1)/vital capacity (VC), either as a fixed value 1/VC ratio in a general population setting. The second aim was to evaluate the characteristics of subjects with COPD who obtained a higher SVC than FVC. Methods: Subjects (n=1,050) aged 50-64 years were i

Palladium seeded GaAs nanowires

In this work, we present a detailed investigation of the growth of palladium-seeded GaAs nanowires. Nanowires grown on GaAs (111)B substrates consist of three different morphologies, denoted as curly (containing multiple kinks), inclined (relative to the substrate, such as 〈001〉), and vertical. We show that the relative yield of the different types is controllable by a combination of V/III ratio a

Cardiovascular and antacid treatment and mortality in oxygen-dependent pulmonary fibrosis : A population-based longitudinal study

BACKGROUND AND OBJECTIVE: Severe idiopathic pulmonary fibrosis is associated with an increased risk of cardiovascular disease and gastro-oesophageal reflux, which may influence prognosis. We evaluated associations between cardiovascular and antacid medications, and mortality, in oxygen-dependent pulmonary fibrosis (PF) of unknown cause.METHODS: Prospective population-based study of adults starting

Generation of cortical neurons from human induced-pluripotent stem cells by biodegradable polymeric microspheres loaded with priming factors

Ischemic stroke is often associated with loss of cortical neurons leading to various neurological deficits. A cell replacement based on stem cell transplantation to repair the damaged brain requires the generation of specific neuronal subtypes. Recently, induced pluripotent stem cells have been used to generate various subtypes of neurons in vitro for transplantation in stroke-damaged brains. Howe

iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma.

A high level of exhaled nitric oxide (NO) is a marker for inflammation in the airways of asthmatic subjects. However, little is known about how NO and inducible nitric oxides synthase (iNOS) activity may affect remodelling in the distal lung. We hypothesized that there is a link between iNOS and ongoing remodelling processes in the distal lung of mild asthmatics.

Regulation of advanced therapy medicinal products in Europe and the role of academia

Background aims. Advanced therapy medicinal products (ATMP) are gene therapy, somatic cell therapy or tissue-engineered products regulated under (EC) No. 1394/2007 to ensure their free movement within the European Union while guaranteeing the highest level of health protection for patients. Academic good manufacturing practice (GMP) centers are major contributors in the development of ATMPs and th

Active signals, gradient formation and regional specificity in neural induction.

The question of how the vertebrate embryo gives rise to a nervous system is of paramount interest in developmental biology. Neural induction constitutes the earliest step in this process and is tightly connected with development of the embryonic body axes. In the Xenopus embryo, perpendicular gradients of BMP and Wnt signals pattern the dorsoventral and anteroposterior body axes. Both pathways nee

Transparent and flexible, nanostructured and mediatorless glucose/oxygen enzymatic fuel cells

Here we detail transparent, flexible, nanostructured, membrane-less and mediator-free glucose/oxygen enzymatic fuel cells, which can be reproducibly fabricated with industrial scale throughput. The electrodes were built on a biocompatible flexible polymer, while nanoimprint lithography was used for their nanostructuring. The electrodes were covered with gold, their surfaces were visualised using s

Biologisk mangfald

Microsoft Word - Biologisk mångfald.docx 2015/16       Botaniska trädgårdar och bevarandet av den biologiska mångfalden Av Fredric Ahrling, NA3a Handledare: Katarina Schiemann POLHEMSKOLAN Abstract   Botanical gardens and sustained biodiversity Due to increased awareness of human impact on nature, awareness of the importance of education regarding the matter has increased as well. By educating chi

https://www.botan.lu.se/sites/botan.lu.se/files/biologisk_mangfald.pdf - 2026-05-20

The modified Borg/6-min walk distance ratio : a method to assess exertional breathlessness and leg discomfort using the 6-min walk test

Background The 6-min walk test (6MWT) is widely used to assess exercise capacity across chronic health conditions, but is currently not useful to assess symptoms, as the scores do not account for the 6-min walk distance (6MWD). We aimed to 1) develop normative reference equations for breathlessness and leg discomfort intensity expressed as modified Borg (mBorg)/6MWD ratios; and 2) validate the equ