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Background Increased postoperative cardiac troponin (cTn) independently predicts short-term mortality. Previous studies suggest that preoperative cTn also predicts major adverse cardiovascular events (MACE) and mortality after noncardiac surgery. The value of preoperative and perioperative changes in cTn as a prognostic tool for adverse outcomes has been sparsely investigated. Methods and findings

OBJECTIVES: This is the first nationwide study with the aim to analyze whether there is an association between country of birth in first-generation immigrants and hospitalization for type 2 diabetes (T2D), and to study whether any such association remains in second-generation immigrants. DESIGN: In this follow-up study, the Swedish Hospital Discharge Register was used to identify all hospital

In neurophysiology, investigating brain connectivity within and between different brain structures is of fundamental importance for understanding nervous system function and its relation to behavior. Yet, parallel recordings in multiple brain structures is highly challenging, especially in rodents, which are most commonly employed in neurophysiological research but rather small in size. In this st

In epidemiological and twin populations, prior interview studies have identified an externalizing spectrum of disorders. Could this be detected utilizing objective registry data? In 20,603 twin pairs from the Swedish Twin Registry, we obtained information from national medical, criminal and pharmacy records on drug abuse (DA), criminal behavior (CB) and alcohol use disorders (AUD). Multivariate tw

Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on European subjects. Methods We performed a two-stage meta-analysis on more than 78 000 participants. In stage 1, we synthesised data from eight GWAS whereas data from 10 centres wer

Risk and vulnerability analyses can play important roles in the society’s proactive emergency management. This thesis addresses two ways of improving the analysis of risk and vulnerability analysis in this context. First, by developing methods for risk and vulnerability analysis of technical infrastructure networks and emergency response systems. Secondly, by aiming to improve practises related to

Obesity is a complex disease with multiple well-defined risk factors. Nevertheless, susceptibility to obesity and its sequelae within obesogenic environments varies greatly from one person to the next, suggesting a role for gene x environment interactions in the etiology of the disorder. Epigenetic regulation of the human genome provides a putative mechanism by which specific environmental exposur

Persistent, itching nodules have been reported to appear at the injection site after allergen-specific immuno-therapy with aluminium-precipitated antigen extract, occasionally in conjunction with contact allergy to aluminium. This study aimed to quantify the development of contact allergy to aluminium during allergen-specific immunotherapy. A randomized, controlled, single-blind multicentre study

Popular Abstract in English Prostate cancer is one of the most common cancers in the world and the second most common in men. The western world has the highest incidence rates. The causes of prostate cancer are not yet clear, however a number of risk factors have been identified such as familial history, ethnicity, diet and genetic events. Prostate cancer affects primarily elderly men with the majProstate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. However their use is still limited by technological problems, lack of standardized procedures and inadequate interpretation. In this work we in

Objective To investigate the 2-year clinical and radiological outcomes of patients with early rheumatoid arthritis (RA; symptom duration <1 year) who had initially responded well to methotrexate monotherapy. Methods In the SWEFOT trial, all 487 patients started methotrexate (target dose 20 mg/week). After 3-4 months, 147 had low disease activity, 28-joint based disease activity score (DAS28) <= 3.

Research on the role of nutrition in type 2 diabetes has largely focused on macro/micronutrient composition and dietary fiber intake, while fewer studies have tested the effects of differing food choice. Some observational studies and short-term intervention studies suggest that a food pattern mimicking the diet with which humans evolved positively influences glucose control and associated endocri

Sensing and manipulating living cells using vertical nanowire devices requires a complete understanding of cell behavior on these substrates. Changes in cell function and phenotype are often triggered by events taking place at the plasma membrane, the properties of which are influenced by local curvature. The nanowire topography can therefore be expected to greatly affect the cell membrane, emphas

OBJECTIVE-A genome-wide association study (GWAS) in Pima Indians (n = 413) identified variation in the ataxin-2 binding protein 1 gene (A2BP1) that was associated with percent body fat. On the basis of this association and the obese phenotype of ataxin-2 knockout mice, A2BP1 was genetically and functionally analyzed to assess its potential role in human obesity. RESEARCH DESIGN AND METHODS-Variant

Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and beta-cell dysfunction but have contributed little to the understanding of the genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance pathways might be uncovered by accounting for differences in body mass index (BMI) and potential interact

VÄLKOMMEN TILL Preliminärt Schema 2015-07-07 VÄLKOMMEN TILL MILJÖVETENSKAP GRUNDKURS - HT 2015 (31/8-01/11) Kursansvarig: Katarina Hedlund 046/2223798, e-mail: Katarina.Hedlund@ekol.lu.se Kurshemsida: http://www.cec.lu.se/sv/utbildning/miljovetenskap-grund-och- avancerad-utbildning/kurser/miljovetenskap-grundkurs-15hp och intern kurskommunikation - http://luvit.ced.lu.se. För att komma in behöver

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvea01_schema_ht15_v2.pdf - 2026-05-07

VÄLKOMMEN TILL Preliminärt Schema 2015-08-17 VÄLKOMMEN TILL MILJÖVETENSKAP GRUNDKURS - HT 2015 (31/8-01/11) Kursansvarig: Katarina Hedlund 046/2223798, e-mail: Katarina.Hedlund@ekol.lu.se Kurshemsida: http://www.cec.lu.se/sv/utbildning/miljovetenskap-grund-och- avancerad-utbildning/kurser/miljovetenskap-grundkurs-15hp och intern kurskommunikation - http://luvit.ced.lu.se. För att komma in behöver

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvea01_schema_ht15_v3.pdf - 2026-05-07

An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood An Age-Related Exponential Decline in theRiskofMultiple Islet Autoantibody Seroconversion During Childhood https://doi.org/10.2337/dc20-2122 OBJECTIVE Islet autoimmunity develops before clinical type 1 diabetes and includes multiple and single autoantibody phenotypes. The objective was to

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/127_MP237_Bonifacio_Diab%20Care_2021.pdf - 2026-05-07

Lunds universitet baspresentation Lunds universitet 2026 | utbildning, forskning och samverkan sedan 1666 Välkommen till Lunds universitet!   Bilden visar Universitetshuset, Lunds universitets huvudbyggnad från 1882 som är ritad av Helgo Zettervall. Sfinxerna på taket är omtyckta symboler för universitetet.   I huset finns den storslagna aulan som används till ceremonier, konserter mm. Här hade oc

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2026-04/LU-baspresentation-2026-SVE-1.pptx - 2026-05-07

U nc or re ct ed A ut ho r P ro of Journal of Parkinson’s Disease xx (2021) x–xx DOI 10.3233/JPD-212609 IOS Press 1 Review1 Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair 2 3 Anders Björklund∗ and Malin Parmar4 Department of Experimental Medical Science, Developmental and Regenerative Neurobiology, Wallenberg Neuroscience Center, Lund University, Lund, Sweden 5 6 Accepted 6 Marc

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/2021-05/publication%20in%20journal%20for%20parkinsons%20disease.pdf - 2026-05-07