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We have generated two reporter plasmids that either monitor expression of human papillomavirus type 16 (HPV16) E2 mRNAs using splice site SA2709 or HPV16 E1C mRNAs utilizing splice site SA2582. In plasmid pE2sLuc, the entire E2 open reading frame was replaced by the secreted luciferase (sLuc) reporter gene and in the pE1nLuc plasmid the E1/E1C open reading frame was fused in frame with the nanoluc
Introduction: The first-line evidence-based treatment for chronic pain is multidisciplinary treatment involving pain-focused CBT. Studies have shown that changes in psychological flexibility (PF) during pain-focused CBT positively mediatesoutcomes, even when the treatment does not specifically target PF. While CBT and PF-based treatments for chronic pain yield small to moderate, but clinically mea
The transformation of CO2 and green hydrogen into methanol presents a sustainable route for chemical and fuel production. Conventional methanol synthesis catalysts, such as Cu/ZnO/Al2O3, employ Al2O3 as a structural promoter, while Ga2O3 has recently emerged as a promising alternative. This study compares Cu-based catalysts supported on Al2O3 (CA) and Ga2O3 (CG), prepared via coprecipitation of la
BackgroundChronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) are characterized by persistent airway inflammation and airflow limitation. Measuring airway inflammation may be of value both in research and clinical practice. Calprotectin, a protein associated with neutrophil activation, serves as a potential biomarker for airway inflammation. This study evaluates the performance o
Inhalation administration of therapeutics is a crucial method for treatment of respiratory diseases, offering direct access to the target organ. However, the progression of candidate drugs is frequently impacted by clinical dose level limitations due to lung histopathological findings or functional effects identified in in vivo studies. Addressing these safety concerns is crucial in advancing comp
Studio recordings of music for English bass horn and string trio from the composers Louis Massonneau, Emma Jane Lloyd, and Ylva Lund Bergner, recorded at the St Cecilia's Hall in Edinburgh on 17 January 2026.
This is a scoping review of low-intensity, home-based interventions promoting learning for 11–17-year-olds in foster care. Research shows that children in out-of-home care fall behind in school compared to their peers. Interventions to improve learning outcomes for these children typically i) target young children or children aging out of care, and ii) require many resources to implement. Lo
Designing composite photocatalytic systems with nanoscale precision is crucial. While conventional facet-selective photo-deposition successfully utilizes spherical co-catalysts, the directed deposition of pre-synthesized two-dimensional (2D) materials onto specific facets remains extremely challenging. This work demonstrates an electrostatic assembly strategy for the precise deposition of 2D trans
Obesity is a stigmatized disease due to pervasive personal, professional, institutional, and cultural weight bias. Individuals with obesity experience weight bias across their lifespan and settings, which can affect their life chances and significantly impact health and social outcomes. The objectives of this study were to: (a) explore weight bias and stigma experiences of people living with obesi
Winter is a critical bottleneck period for many insects and is particularly pivotal for pest species, being a major regulator of their populations. In winter, insect fruit pests such as the invasive fly, Drosophila suzukii, not only have to cope with harsh environmental conditions but also need to find alternative resources when cultivated fruit are scarce. This study aimed to disentangle the rela
Despite being subject to a multitude of investigations, the effect of carrier particle size on the performance of adhesive mixtures for inhalation is still not well understood. This study, involving three differently sized lactose carriers, all with the regular ‘tomahawk’ particle shape, aims to provide fundamental insight into this topic. Fine particle fraction (FPF) data for binary formulations
This paper presents a characterization method for millimeter wave (mmWave) phased array antennas in the mobile terminal for 5G communication. Arrays of different antenna designs, operating at 28 GHz, are evaluated according to novel characterization methods in this context - the total scan pattern of the phased array and its respective coverage efficiency. The results show the relevance of evaluat
Varje dag överlåts företag och företagsgrupper omstruktureras. Ofta rör det sig om stora värden och det är inte ovanligt att en företagsöverlåtelse påverkar de inblandade parterna under lång tid. Skatt är ofta den väsentligaste transaktionskostnaden. Av den anledningen är det mycket viktigt att kunna förutse de skattekonsekvenser som uppkommer i och med överlåtelsen. Beskattning av aktiebolag vi
Abstract in UndeterminedDifferential in-gel electrophoresis (DIGE) experiments allow three protein samples to be run per gel. The three samples are labeled with the spectrally resolvable fluorescent dyes, Cy2, Cy3, and Cy5, respectively. Here, we show that protein-specific dye effects exist, and we present a linear mixed model for analysis of DIGE data which takes dye effects into account. A Java
Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several processes that provide critical external factors for HSC generation. Nevertheless, it is not fully understood how and when the onset of circulation affects HSC emergence. Here we show that in Ncx1−/− mouse embryos devoid of circulation the HSC l
There is a great need to find cheaper but still efficient treatment methods for wastewater. This study aimed to test the purifying performance of three different Moringa oleifera varieties that were cultivated in Tunisia on raw (RUW) and secondary treated urban wastewater (TUW). The seeds of the Mornag, Egyptian, and Indian varieties were powdered, added to the water (at concentrations of 0, 50, 1
A mathematical framework and accompanying numerical algorithm exploiting the continuity equation for 4D reconstruction of spatiotemporal attenuation fields from multi-angle full-field transmission measurements is presented. The algorithm is geared towards rotation-free dynamic multi-beam X-ray tomography measurements, for which angular information is sparse but the temporal information is rich. 3D
