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During epileptic seizures, neuronal network activity is hyper synchronized whereby GABAergic parvalbumin-interneurons may have a key role. Previous studies have mostly utilized 4-aminopyridine to induce epileptiform discharges in brain slices from healthy animals. However, it is not clear if the seizure-triggering ability of parvalbumin-interneurons also holds true without the use of external conv
Background: The aim was to evaluate whether an artificial intelligence (AI)-based tool for the automated quantification of the total metabolic tumour volume (tMTV) in patients with Hodgkin lymphoma (HL) could support nuclear medicine specialists in lesion segmentation and thereby enhance inter-observer agreement. Methods: Forty-eight consecutive patients who underwent staging with [18F]FDG PET/CT
Multidimensional diffusion MRI is a promising new MRI approach that has the potential to non-invasively give information about brain microstructure at an unprecedented level of detail. The present contribution briefly reviews the salient features of the novel method, its historical background and differences with conventional methods, as well as the remaining challenges that have to be overcome in
BACKGROUND: Medium vessel occlusions (MeVO) can be either isolated events (primary), or secondary to thrombus migration from a large vessel occlusion to a medium-sized vessel. Outcomes following endovascular thrombectomy (EVT) in the middle cerebral artery (MCA) may differ between primary and secondary MeVOs. This study aimed to assess the association between primary/secondary MeVOs and clinical o
AimsAtrial septal defects (ASDs) lead to volume-loaded right ventricles (RVs). ASD closure does not always alleviate symptoms or improve exercise capacity, which is possibly explained by impaired left ventricular (LV) haemodynamics. This study evaluated the effect of ASD closure in children using non-invasive LV pressure–volume (PV) loops derived from cardiac magnetic resonance (CMR) imaging and b
IMPORTANCE: Perforated colonic diverticulitis usually requires surgical resection, which is associated with significant morbidity. Cohort studies have suggested that laparoscopic lavage may treat perforated diverticulitis with less morbidity than resection procedures. OBJECTIVE: To compare the outcomes from laparoscopic lavage with those for colon resection for perforated diverticulitis. DESIGN, S
The delay between the origin of animals in the Neoproterozoic and their Cambrian diversification remains perplexing. Animal diversification mirrors an expansion in marine shelf area under a greenhouse climate, though the extent to which these environmental conditions directly influenced physiology and early organismal ecology remains unclear. Here, we use a biogeochemical model to quantify oxygen
Precise knowledge of the temperature during cutting processes is of high interest as the temperature of a cutting tool dictates the performance, and for the workpiece it controls the quality and integrity of the generated surface. For the first time, in this study, a novel technique has been developed utilizing phosphor thermometry for 2D surface temperature measurement of a cutting tool in metal
This article explores the potential for just knowledge production in Urban Living Labs (ULLs) by foregrounding epistemic justice. Drawing on autoethnographic and ethnographic methods, it examines how testimonial and hermeneutical injustices shape the formation, implementation, and dissemination phases of EU-funded, research-led ULLs. Findings show that funding structures, academic framings, and di
Objective: Family members of a person with drug addiction often experience negative impacts on their lives and face barriers to seeking professional support. More knowledge is needed about such barriers so they can be reduced. This article examines the help-seeking experiences of parents of adult children with drug addiction, a group that has received little attention in research. Method: We condu
Uppsatsen handlar om barnets rätt att komma till tals i vårdnadsmål. Rätten fastställs i barnkonventionens artikel 12. Artikeln gäller som lag i Sverige sedan 2020. Enligt artikel 12 ska konventionsstaterna tillförsäkra det barn som är i stånd att bilda egna åsikter rätten att fritt uttrycka dessa i alla frågor som rör barnet. Vidare ska barnet i alla domstolsförfaranden och administrativa förfaraThe topic of the paper is the child's right to be heard in custody cases, as set out in Article 12 of the Convention on the Rights of the Child. The Convention has been in force as law in Sweden since 2020. According to Article 12, States Parties shall assure a child capable of forming his or her own views, the right to express those views freely in all matters affecting the child. Furthermore
Bakgrund: Enligt Socialstyrelsens rekommendationer bör vårdpersonal aktivt uppmuntra föräldrar till närvaro och vård av sitt för tidigt födda barn för att säkerställa deras delaktighet. Svensk neonatalvård anses ligga i framkant men det finns utrymme för förbättringar av det psykosociala stödet och omhändertagandet av föräldrar. Enligt Svenskt Neonatalt Kvalitetsregisters årsrapport 2021 framkomme
Svensson (1997) föreslår att centralbanker på grund av implementerings- och utvärderingssvårigheter hos inflationsmål även bör ha ett mål för inflationsprognoser. Han argumenterar för detta med hjälp av en teoretisk modell som antar att den korta räntan, som centralbanken kontrollerar, påverkar BNP-gapet med en periods fördröjning, vilket sedan påverkar inflationen efter ännu en period. För att ma
The aim of this study was to investigate The Salvation Army's work with human trafficking for sexual purposes since it is a specialized organization in civil society that has a long history of working with this issue. Research shows that overall, the Swedish agencies neither have the competence, nor the knowledge, needed to meet the issue. We, as coming social workers wanted to investigate wha
Segregation är ett föränderligt tillstånd som är komplext och påverkar såväl enskilda individer som samhället i stort. Exempelvis är stadsplaneringen en bakomliggande orsak som kan påverkar segregationen i en stad. För att det verkligen ska kunna ske en förbättring är det emellertid av stor vikt att åtgärder vidtas på olika plan och av olika aktörer. Det ursprungliga syftet bakom arbete är att utSegregation is a changing condition that is complex and affects individuals but also the society. Urban planning is for example an underlying cause that can affect segregation in a city. However, in order for an improvement, it is of great importance that measures are taken at different levels and by different actors. The primary purpose of the report was to study the impact that urban planning h
Introduction: This study evaluated lipid identification using mass spectrometry. Background: Three main modes of acquisition are used in mass spectrometry of lipids; data-independent acquisition (DIA), data-dependent acquisition (DDA) and targeted acquisition. DIA is the most including one, yielding a complete but complex data set, while targeted is the least including one, basing acquisition on
Den här uppsatsen behandlar svensk nationalism i kontexten av programserien ’Allt för Sverige’. Med avstamp i Benedict Anderson teoretiska begrepp ’print capitalism’ diskuteras programseriens funktion som del i svenskt nationskapande. Följande argumenteras det för hur det finns en ambivalens för vad som ryms i konceptet nationell identitet i det moderna Sverige.
