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Lin28b regulation of early-life B lymphopoiesis. A model system to study how self-reactive B cells develop in early life.
Taming of Oxygen in the Electron Microscope : Effects of High Energy Electron Irradiation on O2 and Oxides
Transmission electron microscopy (TEM) is an atomic resolution technique that allows for in depth analysis of the properties of different materials by passing high energy electrons through a thin sample and detecting how they are affected. However, due to the strong interaction between electrons and matter, the probability of the sample remaining unperturbed by the electron irradiation is small. T
The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data
Open science and collaboration are necessary to facilitate the advancement of Parkinson’s disease (PD) research. Hackathons are collaborative events that bring together people with different skill sets and backgrounds to generate resources and creative solutions to problems. These events can be used as training and networking opportunities, thus we coordinated a virtual 3-day hackathon event, duri
Century-long butterfly range expansions in northern Europe depend on climate, land use and species traits
Climate change is an important driver of range shifts and community composition changes. Still, little is known about how the responses are influenced by the combination of land use, species interactions and species traits. We integrate climate and distributional data for 131 butterfly species in Sweden and Finland and show that cumulative species richness has increased with increasing temperature
Towards regenerative regional development in responsible value chains : an agentic response to recent crises
In this paper, we empirically and theoretically present regenerative regional development in responsible value chains as an alternative to the prevailing traditional, neoliberal economic rationale of globalization. We develop the argument on the back of a longitudinal in-depth case study on actors’ engagement in the recurring crises in the maritime industry in Sunnmøre/Norway. The alternative pers
Advantages of binary stochastic synapses for hardware spiking neural networks with realistic memristors
Hardware implementing spiking neural networks (SNNs) has the potential to provide transformative gains in energy efficiency and throughput for energy-restricted machine-learning tasks. This is enabled by large arrays of memristive synapse devices that can be realized by various emerging memory technologies. But in practice, the performance of such hardware is limited by non-ideal features of the m
Understanding passive film degradation and its effect on hydrogen embrittlement of super duplex stainless steel – Synchrotron X-ray and electrochemical measurements combined with CalPhaD and ab-initio computational studies
The passive film stability on stainless steel can be affected by hydrogen absorption and lead to microstructure embrittlement. This work shows that the absorption of hydrogen results in surface degradation due to oxide reduction and ionic defect generation within the passive film, which decomposes and eventually vanishes. The passive film provides a barrier to entering hydrogen, but when hydrogen
Light-Controlled Multiphase Structuring of Perovskite Crystal Enabled by Thermoplasmonic Metasurface
Halide perovskites belong to an important family of semiconducting materials with electronic properties that enable a myriad of applications, especially in photovoltaics and optoelectronics. Their optical properties, including photoluminescence quantum yield, are affected and notably enhanced at crystal imperfections where the symmetry is broken and the density of states increases. These lattice d
From senses to sensors : autonomous cars and probing what machine learning does to mobilities studies
Cars are nowadays being programmed to learn how to drive themselves. While autonomous cars are often portrayed as the next step in the auto-motive industry, they have already begun roaming the streets in some US cities. Building on a growing body of critical scholarship on the development of autonomous cars, we explore what machine learning is in open environments like cities by juxtaposing this t
Long-term exposure to traffic noise and risk of incident colon cancer : A pooled study of eleven Nordic cohorts
Background Colon cancer incidence is rising globally, and factors pertaining to urbanization have been proposed involved in this development. Traffic noise may increase colon cancer risk by causing sleep disturbance and stress, thereby inducing known colon cancer risk-factors, e.g. obesity, diabetes, physical inactivity, and alcohol consumption, but few studies have examined this. Objectives The o
Life and Death of Mixed Metal Halide Perovskites : Mechanism and Consequences of Light Induced Halide Segregation in MAPb(I,Br)3
Metal halide perovskites have attracted immense scientific interest due to their outstanding optoelectronic properties over a widebandgap range. Applications cover a wide range of optoelectronic devices from solar cells, LEDs and lasers to X-ray detectors.[1,2] Particularly in combination with existing silicon technology, perovskite-silicon tandem solar cells, which achieve power conver-sion effic
Quantification of the inhaled deposited dose during sand and dust storms
Exposure to dust particles during a sand and dust storm (SDS) can be harmful for health. The first step to understand the health effects of such exposure is to quantify the amount of deposited dust particles in the respiratory tracts. In this book chapter, a brief summary is presented about: (1) the outbreak mechanisms dust particles and being airborne, (2) physical and chemical characteristics of
Dynamical Analysis of Terahertz Quantum Cascade Lasers
This thesis focuses on various aspects in terahertz quantum cascade lasers such as high temperature performances, electrical instabilities and chaos. In the first part of the thesis, an introduction to the topic and the non equilibrium Green's function package applied is given with particular emphasise on the inhomogeneous domain model and the chaos theory. In addition, new results regarding the h
Use of Virtual Reality in Psychiatric Diagnostic Assessments : A Systematic Review
BACKGROUND: Technological developments such as Virtual reality (VR) provide new opportunities to extend and innovate mental healthcare. VR as a tool for clinical assessment has been described as promising, as it can enable real-time assessment within real-like environments or contexts as opposed to self-report and behavioral tasks in laboratory settings.OBJECTIVE: With this systematic review we ai
Epigenetics of methylmercury
Purpose of review: Methylmercury (MeHg) is neurotoxic at high levels and particularly affects the developing brain. One proposed mechanism of MeHg neurotoxicity is alteration of the epigenetic programming. In this review, we summarise the experimental and epidemiological literature on MeHg-associated epigenetic changes. Recent findings: Experimental and epidemiological studies have identified chan
The effects of sociodemographic factors and comorbidities on sepsis: A nationwide Swedish cohort study
Sepsis is a severe condition, representing a significant public health concern, especially in the elderly. There is, however, little insight into the potential effects of sociodemographic factors and comorbidities on sepsis incidence and how these factors interact. This was a nationwide open cohort study including individuals (N = 6746010) in Sweden ≥ 18 years of age spanning from 1997 to 2018, wi
Forensic psychiatric patients’ experiences of participating in administrative court proceedings concerning the continuation of forensic psychiatric care
Introduction: Previous studies show that both staff and patients describe patient participation as a challenge in forensic psychiatry. One reason may be that the forensic psychiatric process is difficult to understand and is experienced as being slow and complex. The proceedings in an administrative court are a core element in forensic psychiatric care as it constitutes the legal authority that le
Assembly of Multicompartment Glycopolymer Worms in Aqueous Solution
Hierarchical self-assembly is a versatile technique that allows the formation of many complex architectures on the nano- and microscale. However, many of these structures are formed in harsh organic solvents with nonbiocompatible polymers. Here, we investigate in more detail a synthetic path to produce biologically compatible, crosslinked, multicompartment worms (MCWs) in aqueous solution by incor
Halide Perovskite Artificial Solids as a New Platform to Simulate Collective Phenomena in Doped Mott Insulators
The development of quantum simulators, artificial platforms where the predictions of many-body theories of correlated quantum materials can be tested in a controllable and tunable way, is one of the main challenges of condensed matter physics. Here we introduce artificial lattices made of lead halide perovskite nanocubes as a new platform to simulate and investigate the physics of correlated quant
