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Thermal performance of angled, V-shaped and leaning-V-shaped ribs in a rotating rectangular channel with 45° orientation

Purpose: The fluid flow in a rotating channel is obviously different from that in a stationary channel due to the existence of Coriolis force, which, in turn, enhances the heat transfer on the trailing side and reduces the heat transfer on the leading side. The purpose of this paper is to study various rib configurations combined with channel orientation on heat transfer and frictional loss in a r

Computational analysis of span-wise hole locations on fluid flow and film cooling of internal channels with crescent ribs

Purpose: This study aims to clarify the mechanism of film hole location at the span-wise direction of an internal cooling channel with crescent ribs on the adiabatic film cooling performance, three configurations are designed to observe the effects of the distance between the center of the ellipse and the side wall(Case 1, l = w/2, Case 2, l = w/3 and for Case 3, l = w/4). Design/methodology/appro

Proenkephalin a 119-159 (penKid) - a novel biomarker for acute kidney injury in sepsis : an observational study

Background: Sepsis is a leading cause of death worldwide and a major challenge for physicians to predict and manage. Proenkephalin A 119-159 (penKid) is a reliable surrogate marker for the more unstable endogenous opioid peptide enkephalin, which has previously been shown to predict both acute and chronic kidney disease. The aim of this prospective observational study was to assess penKid as a pre

Cardiovascular biomarkers and echocardiographic findings at rest and during graded hypovolemic stress in women with recurrent vasovagal syncope

Introduction: Vasovagal reflex is the most common type of syncope but its etiology is not fully elucidated. Venous return and cardiac output are key in hemodynamic control. The aim of the study was to assess cardiovascular biomarkers and echocardiographic measures at rest and during hypovolemia in women with and without a history of vasovagal syncope. Methods: Fourteen women (aged 18-30) suffering

Blood Perfusion in Rotational Full-Thickness Lower Eyelid Flaps Measured by Laser Speckle Contrast Imaging

PURPOSE: Large upper eyelid defects can be repaired by rotational full-thickness lower eyelid flaps. The aim was to measure the blood perfusion in such flaps, and how it is affected by the length of the flaps, and the degree of rotation and stretching.METHODS: Nine patients underwent the Quickert procedure for entropion repair in which a full-thickness eyelid flap of approximate width 0.5 cm and l

Potential and limits of a colloid approach to protein solutions

Looking at globular proteins with the eyes of a colloid scientist has a long tradition, in fact a significant part of the early colloid literature was focused on protein solutions. However, it has also been recognized that proteins are much more complex than the typical hard sphere-like synthetic model colloids. Proteins are not perfect spheres, their interaction potentials are in general not isot

Characteristics of Particulate Emissions from Low Temperature Combustion and Renewable Fuels : Aerosol Mass Spectrometry of Refractory Carbonaceous Particles

Particulate air pollution is one of the major causes of premature death in the world, and combustion-derived soot emissions contribute strongly to the particulate pollution to which humans are exposed. Black carbon (BC) is one such emission and denotes soot with strong light absorption in the ultraviolet to infrared spectrum. Combustion can also generate brown carbon (BrC) particles, with absorpti

Predicted basal metabolic rate and cancer risk in the European Prospective Investigation into Cancer and Nutrition

Emerging evidence suggests that a metabolic profile associated with obesity may be a more relevant risk factor for some cancers than adiposity per se. Basal metabolic rate (BMR) is an indicator of overall body metabolism and may be a proxy for the impact of a specific metabolic profile on cancer risk. Therefore, we investigated the association of predicted BMR with incidence of 13 obesity-related

Risk factors for subarachnoid haemorrhage : a nationwide cohort of 950 000 adults

BACKGROUND: Subarachnoid haemorrhage (SAH) is a devastating disease, with high mortality rate and substantial disability among survivors. Its causes are poorly understood. We aimed to investigate risk factors for SAH using a novel nationwide cohort consortium. METHODS: We obtained individual participant data of 949 683 persons (330 334 women) between 25 and 90 years old, with no history of SAH at

Lipid dynamics and phase transition within α-synuclein amyloid fibrils

The deposition of coassemblies made of the small presynaptic protein, α-synuclein, and lipids in the brains of patients is the hallmark of Parkinson's disease. In this study, we used natural abundance 13C and 31P magic-angle spinning nuclear magnetic resonance spectroscopy together with cryo-electron microscopy and differential scanning calorimetry to characterize the fibrils formed by α-synuclein

Impact of Cardiovascular Neurohormones on Onset of Vasovagal Syncope Induced by Head-up Tilt.

BackgroundVasovagal reflex is the most common form of syncope, but the pathophysiological mechanisms that initiate the reflex are not well understood. We aimed to study supine and early orthostatic levels of the neurohormones involved in control of circulatory homeostasis in relation to the onset of tilt‐induced vasovagal syncope (VVS).Methods and ResultsA total of 827 patients who were investigat

Neurobehavioral symptoms in children born extremely preterm : A Swedish National Study

Aim: To determine the prevalence of neurobehavioral symptoms at 6.5 years in children born extremely preterm (EPT, <27 weeks' gestation). Methods: Population-based cohort study of infants born EPT in Sweden from 2004 to 2007. Of 486 survivors 375 were assessed and compared with 369 matched term-born controls. EPT children free from neurosensory and intellectual disabilities (neurodevelopmental dis