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The retinacular ligaments of the digital extensor expansion revisited : An anatomical and biomechanical study

Our aim was to clarify the anatomy and function of the retinacular ligaments. Forty-eight fingers were dissected and the thickness of the oblique retinacular ligament (ORL) was graded. In four fingers, the motion in the proximal interphalangeal (PIP) and distal interphalangeal (DIP) joints was subjected to an in-depth analysis before and after sectioning of either the lateral bands (LB) or the ORL

Characterization of the internal working-life exposome using minimally and non-invasive sampling methods - a narrative review

During recent years, we are moving away from the ‘one exposure, one disease’-approach in occupational settings and towards a more comprehensive approach, taking into account the totality of exposures during a life course by using an exposome approach. Taking an exposome approach however is accompanied by many challenges, one of which, for example, relates to the collection of biological samples. M

Particle Adsorption Using a Quartz Crystal Microbalance with Dissipation by Applying a Kelvin-Voigt-Based Viscoelastic Model and the Gauss-Newton Method

The use of a quartz crystal microbalance with dissipation (QCM-D) to study the adsorption of particles larger than 100 nm, such as liposomes, viruses, and nano/micro-plastics, remains challenging owing to the lack of appropriate models for data evaluation. This study presents a method for quantifying the adsorption of negatively charged polystyrene latex (100 nm-1 μm) at the solid-liquid interface

Cumulative live birth rate after IVF : Trend over time and the impact of blastocyst culture and vitrification

STUDY QUESTION: Has cumulative live birth rate (CLBR) improved over time and which factors are associated with such an improvement? SUMMARY ANSWER: During an 11-year period, 2007-2017, CLBR per oocyte aspiration increased significantly, from 27.0% to 36.3%, in parallel with an increase in blastocyst transfer and cryopreservation by vitrification. WHAT IS KNOWN ALREADY: While it has been shown that

A Swedish nationwide forensic study of the manner of death in single stab injuries to the trunk

Introduction Forensic pathologists are frequently confronted with questions about whether an injury is likely to have been inflicted by an assault or be self-inflicted. However, little is known of the epidemiological variables that might be applicable to differentiate between homicides and suicides in deaths caused by single stab injuries to the trunk. Method Using the Swedish forensic autopsy reg

Blocking IL1RAP on cancer-associated fibroblasts in pancreatic ductal adenocarcinoma suppresses IL-1-induced neutrophil recruitment

Background Pancreatic ductal adenocarcinoma (PDAC) represents a major clinical challenge due to its tumor microenvironment, which exhibits immune-suppressive properties that facilitate cancer progression, metastasis, and therapy resistance. Interleukin 1 (IL-1) signaling has been implicated as a driver in this process. Mechanistically, both IL-1α and IL-1β bind to the IL-1 receptor type 1, forming

Misdiagnosis in breast imaging : a statement paper from European Society Breast Imaging (EUSOBI)—Part 2: Main causes of errors in breast imaging and recommendations from European Society of Breast Imaging to limit misdiagnosis

Importance: Breast cancer is one of the leading causes of negligence claims in radiology. The objective of this document is to describe the specific main causes of errors in breast imaging and provide European Society of Breast Imaging (EUSOBI) recommendations to try to minimize these. Observations: Technical failures represent 17% of all mammographic diagnostic negligence claims. Mammography qual

Opening the Black Box of III-V Nanowire Growth

Group III-V semiconductor nanowires are a material platform with potential applications in electronics,photovoltaics and optoelectronic devices. One of the central challenges in the growth of III-V semiconductornanowires is to understand the dynamic processes that occur during crystallization. However, the growth of thesematerials is commonly performed in closed systems. There the details of the g

The neuroethology of ant navigation

Unlike any other group of animals, all ant species are social: individual ants share the food they gather with their nestmates and as a consequence they must repeatedly leave their nest to find food and then return home with it. These back-and-forth foraging trips have been studied for about a century and much of our growing understanding of the strategies underlying animal navigation has come fro

Memory State Dynamics in BEOL FeFETs : Impact of Area Ratio on Analog Write Mechanisms and Charging

This work presents dynamic state writing by combining ferroelectric (FE) polarization together with charge injection (CI) on Si-based ferroelectric MOSFETs as a novel approach for non-volatile memory design. FE capacitors are non-destructively integrated in the Back-End-of-Line (BEOL) with Si MOSFETs to create FE-Metal-FETs (FeMFETs). We explore the FE/MOS area ratio (AR) as a critical design para

Tracing Chemical Alterations in Cancer Cells and Tissues

Cancer is a leading cause of death worldwide, with approximately ten million people dying from the disease each year. In most cases, cancer metastasizes to distant organs and develops resistance to therapy, highlighting the need for novel biomarkers for early detection. This thesis investigates the role of lipid metabolism changes, particularly involving cholesterol and related lipid species, as e

Model-Fitting Weighted Least Squares as an alternative to Principal Component Analysis for Analyzing Energy-Dispersive X-ray Spectroscopy Spectrum Images

Spectrum imaging with energy-dispersive X-ray spectroscopy (EDS) has become ubiquitous in material characterization using electron microscopy. Multivariate statistical methods, commonly principal component analysis (PCA), are often used to aid analysis of the resulting multidimensional datasets; PCA can provide denoising prior to further analysis or grouping of pixels into distinct phases with sim

In-cycle evolution of thickness and roughness parameters during oxygen plasma enhanced ZnO atomic layer deposition using in situ spectroscopic ellipsometry

We investigate the time evolution of ZnO thin film growth in oxygen plasma-enhanced atomic layer deposition using in situ spectroscopic ellipsometry. The recently proposed dynamic-dual-box-model approach [Kilic et al., Sci. Rep. 10, 10392 (2020)] is used to analyze the spectroscopic data post-growth. With the help of this model, we explore the in-cycle surface modifications and reveal the repetiti

Circulating Proneurotensin Levels Predict Impaired Bone Mineralisation in Postmenopausal Women With Type 2 Diabetes Mellitus

Context: The mechanisms underlying bone fragility and increased fracture risk observed in individuals with type 2 diabetes (T2D) are not yet fully elucidated. Previous research has suggested a role for neuropeptides in regulating bone metabolism; however, the contribution of the neuropeptide Neurotensin (NT), which is thoroughly implicated in T2D and cardiovascular disease, has not been investigat

In Situ X-Ray Study During Thermal Cycle Treatment Combined with Complementary Ex Situ Investigation of InGaN Quantum Wells

In situ X-ray reciprocal space mapping was performed during the interval heating and cooling of InGaN/GaN quantum wells (QWs) grown via metal–organic vapor phase epitaxy (MOVPE). Our detailed in situ X-ray analysis enabled us to track changes in the peak intensities and radial and angular broadenings of the reflection. By simulating the radial diffraction profiles recorded during the thermal cycle

In Situ Growth of GaP Nanowires with Alternative Seed Materials

The growth of III-V nanowires has attracted significant attention due to their superior electrical and optical properties, which are crucial for advanced optoelectronic devices such as lasers and photonic circuits. Since the 1960s, Au has beenextensively used as a catalyst for III-V nanowire growth, with substantial research conducted through both ex situ and in situ techniques. However, Au introd

Unfolding the Mystery of Autoimmunity : The Environmental Determinants of Diabetes in the Young (TEDDY) Study

In 2025, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health celebrates 75 years of leadership in diabetes research. The NIDDK serves people of the U.S. affected by or at risk for many chronic diseases, including diabetes and other endocrine, metabolic, and digestive disorders, by funding innovative research to develop better treatment

Current noise in quantum dot thermoelectric engines

We theoretically investigate a thermoelectric heat engine based on a single-level quantum dot, calculating average quantities such as current, heat current, output power, and efficiency, as well as fluctuations (noise). Our theory is based on a diagrammatic expansion of the memory kernel together with counting statistics, and we investigate the effects of strong interactions and next-to-leading or

Theory of transport in lowdimensional nanostructures

This thesis theoretically investigates electronic transport in different low dimensional nanostructures. The miniaturization of electronics means that we reach a limit where quantum effects play a role in electronic devices. To understand and improve electronics at this level it is important to understand the transport properties. Excellent control over the nanostructures also makes them a great p

A balancing act : towards a conceptual framework for the governance of buyer-supplier relationships in defence supply chains

Against the backdrop of the current geopolitical situation, logistics preparedness emerges as a pivotal area of focus for defence supply chains. Despite the critical role of commercial suppliers, research on utilising these in defence logistics and supply chains remains scarce. Adopting a supply chain governance lens, we have conducted a systematic literature review to provide an overview of exist