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Team Coordination in Escalating Situations: An Empirical Study Using Mid-Fidelity Simulation

The performance of teams, with different levels of domain and crisis management experience, managing unexpected and escalating situations was observed using a mid-fidelity ship-bridge simulation and analysed by applying the central concepts of joint activity coordination as well as Woods’s theory building on data overload. The coordination strategies used by the teams were evaluated by applying coo

Retardation of Abeta fibril formation by phospholipid vesicles depends on membrane phase behavior.

An increasing amount of evidence suggests that in several amyloid diseases, the fibril formation in vivo and the mechanism of toxicity both involve membrane interactions. We have studied Alzheimer's disease related amyloid beta peptide (Abeta). Recombinant Abeta(M1-40) and Abeta(M1-42) produced in Escherichia coli, allows us to carry out large scale kinetics assays with good statistics. The amyloi

Development and evaluation of the aerosol dynamics and gas phase chemistry model ADCHEM

The aim of this work was to develop a model suited for detailed studies of aerosol dynamics, gas and particle phase chemistry within urban plumes, from local scale (1x1 km(2)) to regional scale. This article describes and evaluates the trajectory model for Aerosol Dynamics, gas and particle phase CHEMistry and radiative transfer (AD-CHEM). The model treats both vertical and horizontal dispersion p

Revised equations for estimating glomerular filtration rate based on the Lund-Malmö Study cohort.

Abstract Objective. To increase the accuracy of estimated GFR (eGFR) from creatinine overall and at measured GFR ≥90 mL/min per 1.73 m(2) by revising the Lund-Malmö (LM) equations, to elaborate on more complex forms to improve the LM and CKD-EPI equations further, and to assess benefits of adding lean body mass (LBM). Material and methods. Swedish Caucasians (n = 850, 376 women; median 60, range 1

Induction of T helper 2 responses against human Apolipoprotein B100 does not affect atherosclerosis in ApoE-/- mice.

Immune responses against LDL antigens have been found to play an important modulatory role in atherosclerosis. Immunization with homologous oxidized LDL, as well as human apolipoprotein B100 (ApoB)-derived peptides, inhibit atherosclerosis in hypercholesterolemic animal models of atherosclerosis. However, the role of antigen-specific Th2 responses in atherosclerosis remains to be fully clarified.

Maternal Physical Activity and Insulin Action in Pregnancy and Their Relationships With Infant Body Composition.

OBJECTIVEWe sought to assess the association between maternal gestational physical activity and insulin action and body composition in early infancy.RESEARCH DESIGN AND METHODSAt 28-32 weeks, gestation, pregnant women participating in an observational study in Sweden underwent assessments of height, weight, and body composition, an oral glucose tolerance test, and 10 days of objective physical act

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.

In this study, we have used a microRNA-regulated lentiviral reporter system to visualize and segregate differentiating neuronal cells in pluripotent cultures. Efficient suppression of transgene expression, specifically in undifferentiated pluripotent cells, was achieved by using a lentiviral vector expressing a fluorescent reporter gene regulated by microRNA-292. Using this strategy, it was possib

Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease.

Patients with systemic lupus erythematosus (SLE) have a markedly increased risk to develop cardiovascular disease, and traditional cardiovascular risk factors fail to account for this increased risk. We used microarray to probe the platelet transcriptome in individuals with SLE and healthy controls, and the gene and protein expression of a subset of differentially expressed genes was further inves

Tired of Diabetes Genetics? Circadian Rhythms and Diabetes: The MTNR1B Story?

Circadian rhythms are ubiquitous in biological systems and regulate metabolic processes throughout the body. Misalliance of these circadian rhythms and the systems they regulate has a profound impact on hormone levels and increases risk of developing metabolic diseases. Melatonin, a hormone secreted by the pineal gland, is one of the major signaling molecules used by the master circadian oscillato

The Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.

Observational studies show an association between ferritin and type 2 diabetes (T2D), suggesting a role of high iron stores in T2D development. However, ferritin is influenced by factors other than iron stores, which is less the case for other biomarkers of iron metabolism. We investigate associations of ferritin, transferrin saturation (TSAT), serum iron, and transferrin with T2D incidence to cla

A new tool for predicting the probability of chronic kidney disease from a specific value of estimated GFR.

Abstract Objective. To demonstrate how patients' probability of having chronic kidney disease (CKD) stage 3-5 (measured GFR <60 mL/min/1.73 m(2)) can be predicted from a specific value of estimated glomerular filtration rate (eGFR). Material and methods. The probability of CKD stage 3-5 was predicted from a logistic regression model (n = 850) using three different eGFR prediction equations: Lund-M

Intraventricular Extension of Supratentorial Intracerebral Hemorrhage: The Modified Graeb Scale Improves Outcome Prediction in Lund Stroke Register.

The modified Graeb Scale (mGS) is a semi-quantitative method to assess the extension of intraventricular hemorrhage (IVH) in patients with intracerebral hemorrhage (ICH). The mGS has been shown to prognosticate outcome after ICH in cohorts derived from convenience samples. We evaluated the external validity of mGS in supratentorial ICH-patients from an unselected cohort.

Lower educational level is a predictor of incident type 2 diabetes in European countries: The EPIC-InterAct study.

BACKGROUND: Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide. In high-income countries, low socioeconomic status seems to be related to a high incidence of T2DM, but very little is known about the intermediate factors of this relationship. METHOD: We performed a case-cohort study in eight Western European countries nested in the EPIC study (n = 340 234, 3.99

Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort.

OBJECTIVE: To identify predictors of sick leave and disability pension in patients with early rheumatoid arthritis (RA). METHODS: Individuals aged 19-59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999-2007; n=3029). We retrieved days of sick leave and disability pension from the Swedish Social Insurance Agency and basel

The Marketing of Traditional Vegetable Seeds - How the EU legislation affects the conservation and sustainable use of plant genetic resources

Syftet med denna uppsats är att undersöka hur Europeiska Unionens (EU) lagstiftning avseende saluföring av utsäde av köksväxter påverkar mångfalden av växtgenetiska resurser samt att utreda potentiella förbättringsförslag till den nuvarande lagstiftningen. EU:s utsädeslagstiftning består främst av direktiv 2002/55 som anger att enbart certifierat utsäde från registrerade sorter får saluföras i EU The main purpose of this essay is to investigate how the European Union’s (EU) vegetable seed marketing legislation affects the diversity of plant genetic resources and to examine possible improvement to further this diversity. The EU seed legislation consists of directive 2002/551 which provides that only certified seeds from registered varieties may be sold in the EU, and of directive 2009/1452.

Hur verkligt är verkligt värde? En studie om informationsasymmetri vid börsintroduktioner utifrån IFRS 13 värderingshierarki

Titel: Hur verkligt är verkligt värde? En studie om underprissättning vid börsintroduktioner Seminariedatum: 2 juni 2023 Kurs: FEKH69 – Examensarbete i redovisning på kandidatnivå Författare: Oskar Brunnéd, Simon Sandström, Jamal Shamma Handledare: Liesel Klemcke Syfte: Studien syftar till att undersöka ifall underprissättningen vid börsintroduktioner på Stockholmsbörsen och Nordic Growth Ma