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Mechanisms of therapy resistance in acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is a highly aggressive pediatric cancer that can affect both B cells and T cells. The advent of new therapies has increased the cure rates for both B-ALL and T-ALL patients. However, some patients still experience relapse with a variable response to the treatment and display poor survival. Thus,identification of novel predictive biomarkers that can predict therap

Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury

Brain injuries can interrupt descending neural pathways that convey motor commands from the cortex to spinal motoneurons. Here, we demonstrate that a unilateral injury of the hindlimb sensorimotor cortex of rats with completely transected thoracic spinal cord produces hindlimb postural asymmetry with contralateral flexion and asymmetric hindlimb withdrawal reflexes within 3 hr, as well as asymmetr

Interaction Effect Between Copy Number Variation in Salivary Amylase Locus (AMY1) and Starch Intake on Glucose Homeostasis in the Malmö Diet and Cancer Cohort

Salivary amylase initiates the digestion of starch and it has been hypothesized that salivary amylase may play a role in the development of insulin resistance and type 2 diabetes. The aim was to examine the interaction between copy number variation in the salivary amylase gene AMY1 and starch intake. We studied 3,624 adults without diabetes or elevated blood glucose in the Malmö Diet Cancer cohort

Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts

We tested whether pregnant and non-pregnant women differ in COVID-19 symptom profile and severity, and we extended previous investigations on hospitalized pregnant women to those who did not require hospitalization. Two female community-based cohorts (18–44 years) provided longitudinal (smartphone application, N = 1,170,315, n = 79 pregnant tested positive) and cross-sectional (web-based survey, N

Predictors of unacceptable pain with and without low inflammation over 5 years in early rheumatoid arthritis-an inception cohort study

OBJECTIVES: Pain is a major symptom in patients with rheumatoid arthritis (RA). In early RA, pain is usually due to synovitis, but can also persist despite effective anti-inflammatory treatment. The objective of this study was to investigate the pain course over time and predictors of unacceptable pain and unacceptable pain with low inflammation, in patients with early RA.METHODS: An inception coh

Risk, Resilience and Insurance in Sudanese Pastoralism

The nomadic pastoralists of the Sahel are often identified as a group at the frontline of global climate change. Their existence in arid and semi-arid regions and their reliance on seasonal rainfall are among the factors that contribute to their vulnerability to drought and climate shocks. This study focuses on risks to pastoralists in Sudan, asking whether index-based livestock insurance, an innoPastoralism is a nomadic lifestyle and a livelihood system that revolves around raising livestock. By migrating seasonally in search of water and pasture for their animals, pastoralists are able to inhabit and make productive use some of the world’s harshest environments. In Sudan, where over 90% of the vast land area is covered by desert and drylands, pastoralism remains a vital feature of the co

Ansvar för att skapa hållbarhet : en begreppsanalys av ansvar i den svenska modeindustrins hållbarhetsredovisningar

My thesis ’’Responsibility to create sustainability – a concept analysis of responsibility in the sustainability reports of the Swedish fashion industry’’, investigates Hennes & Mauritz and Filippa Ks view of the concept responsibility in sustainability reports, be- fore and after the adoption of The Sustainable development goals. The purpose of this study is to uncover if the enterprises view

Spela för att läsa! En studie om GraphoLearns effekter på avkodningsförmåga hos barn i åldrarna 6 till 7 år

Syfte: Huvudsyftet med studien var att undersöka den phonicsbaserade lärappen GraphoLearns effekter på avkodningsförmågan hos svensktalande barn i tidig läsutveckling. Sekundärt var syftet att undersöka huruvida träning med GraphoLearn kan påverka hjärnstruktur. Studien kan betraktas som en pilotstudie för ett större pågående projekt. Metod: Fjorton deltagare i åldrarna 6 till 7 år inkluderades. S

”Hjärtat slår och det känns som dom håller på att dö eller svimma” : en kvalitativ studie av hur lärare kan arbeta med talrädsla vid muntliga framställningar i svenskämnet i gymnasieskolan

I denna uppsats står rädsla för att tala i fokus. Talrädsla belyses med retorikämnet som grund, och studien tar avstamp i den svenska gymnasieskolan. Syftet med studien är att ta fram ett handfast material för hur svensklärare på gymnasieskolan kan arbeta med talrädda elever. För att uppnå syftet genomförs en litteraturstudie, där handböcker som behandlar området talrädsla studeras. I dessa handböIn this study, language anxiety is in focus. Language anxiety is studied with the subject of rhetoric as a basis, and the study is based on the Swedish upper secondary school. The aim of the study is to produce a solid material for how Swedish teachers at upper secondary school can work with students with language anxiety. In order to achieve this purpose, a literature study is carried out, in whi

Zeynep saglam

Microsoft Word - LUMES THESIS_May2008_Zeynep Saglam.doc Multi Stakeholder Platforms as a Way towards Sustainable Water Basin Management: The Case of Istanbul's Ömerli Basin Author: Zeynep Sağlam zeynep.saglam@gmail.com Supervisor: Prof. Dr. Erdoğan Yüzer yuzer@itu.edu.tr Istanbul Technical University Geological Engineering Department A Thesis Submitted to Lund University International Master’s Pro

https://www.lumes.lu.se/sites/lumes.lu.se/files/zeynep_saglam.pdf - 2026-05-24

Karkee krishna

1 Effects of Deforestation on Tree Diversity and Livelihoods of Local Community: A Case Study from Nepal By Krishna Karkee PO Box: 170 222 00 Lund, Sweden krishna.karkee.142@student.lu.se A thesis submitted to the Lund University International Master’s Programme in Environmental Science (LUMES) in partial fulfillment of the requirements for the degree of Master of Environmental Science Advisor Pro

https://www.lumes.lu.se/sites/lumes.lu.se/files/karkee_krishna.pdf - 2026-05-24

Course Guide PX36003 V23 Gerontologi - Flervetenskapliga Och Integrativa Perspektiv På Åldrandet

Course Guide : PX36003 V23 Gerontologi - flervetenskapliga och integrativa perspektiv på åldrandet Course Guide The course Gerontology – Multidisciplinary and Integrative Perspectives on Aging consists of two sub- courses with a total of 5 (3+2) higher education credits (HEC): 1. Perspectives on aging, 3HEC 2. Implementation in own research (optional), 2HEC Please indicate in the Poll whether or n

https://www.sweah.lu.se/en/sites/sweah.lu.se.en/files/2024-11/Course%20Guide%20_%20PX36003%20V23%20Gerontologi%20-%20flervetenskapliga%20och%20integrativa%20perspektiv%20pa%CC%8A%20a%CC%8Aldrandet%5B83%5D.pdf - 2026-05-24

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Possible heterogeneity of initial pancreatic islet beta‐cell autoimmunity heralding type 1 diabetes Review-Symposium doi: 10.1111/joim.13648 Possible heterogeneity of initial pancreatic islet beta-cell autoimmunity heralding type 1 diabetes Åke Lernmark1 , Beena Akolkar2, William Hagopian3, Jeffrey Krischer4, Richard McIndoe5, Marian Rewers6, Jorma Toppari7, Kendra Vehik4, Anette-G. Ziegler8 & The

https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-11/151_2.pdf - 2026-05-24

No title

Last updated November 17, 2025 COSM27: International Relations of East and South-East Asia Literature List Spring Semester 2026 Approved on 18 November 2026 by the education board at the Centre for East and South-East Asian Studies. Literature introduction The course literature is selected to encompass a broad range of theories and topics, reflecting a diversity of views on contemporary internatio

https://www.ht.lu.se/media/utbildning/dokument/kurser/COSM27/20261/COSM27_2026_literature_list.docx - 2026-05-21

Civilingenjörsutbildning i teknisk matematik utbildningsplan

Civilingenjörsutbildning i teknisk matematik utbildningsplan Sida 1 av 7 Utbildningsplan Civilingenjörsutbildning i teknisk matematik - Programkod: TATPI - Omfattning: 300 högskolepoäng - Tillträdesnivå: Grundnivå - Beslutsfattare: Programledning F/Pi - Utbildningsplanens giltighet: 2025/2026 - Utbildningsplanen fastställd: 2025-02-13 1 Syfte och mål 1.1 Syfte Matematik har i alla tider spelat en

https://www.student.lth.se/fileadmin/lth/student/Utbildningsplaner_2023_och_fram/Grund_svenska/25_26/Utbildningsplan_Civilingenjoersutbildning_i_teknisk_matematik_25-26.pdf - 2026-05-23

HILMA

HILMA HILMA Historiska Institutionen i Lund meddelar Att… Årgång 31, 2005/06, Nr 12, 2006-06-07 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansökningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat pärm, kopierar du och sätter tillb

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_vt06_07.pdf - 2026-05-23