Filetype
Purpose - With the development of electronic devices, including the desires of integration, miniaturization, high performance and the output power, cooling requirement of chips have been increased gradually. Water-cooled minichannel is an effective cooling technology for cooling of heat sinks. The minichannel flow geometry offers large surface area for heat transfer and a high convective heat tran
Aims/hypothesis Post-translational modifications, such as isomerisation of native proteins, may create new antigenic epitopes and play a role in the development of the autoimmune response. Protein-L-isoaspartate (D-aspartate) O-methyltransferase (PIMT), encoded by the gene PCMT1, is an enzyme that recognises and repairs isomerised Asn and Asp residues in proteins. The aim of this study was to asse
A numerical algorithm is presented for the problem of a crack along the interface of an elastic inclusion embedded in an elastic plane subjected to uniform stress at infinity. The algorithm is based on a Fredholm integral equation of the second kind and allows for fast and accurate solutions to geometries of great complexity. In an example crack opening displacement and stress intensity factors ar
While prior research has often used psychological characteristics to identify entrepreneurs and entrepreneurial behaviour, little has been done to predict venture performance. This study examines the impact of four entrepreneurial characteristics on venture performance. The findings are mixed with previous research but provide a new insight by exploring the characteristics of entrepreneurs in gene
Abstract in UndeterminedThis paper presents a new and improved bit-serial CORDIC architecture. A detailed description of the bit-serial implementation and its Control Unit is presented. It is shown that the improvement is due to a reduction of registers in the implementation and is made possible by ensuring that the angular path is calculated prior to the corresponding vector paths. In addition, t
In Parkinson's disease, the degeneration of dopaminergic neurons in substantia nigra leads to a decrease in the physiological levels of dopamine in striatum. The existing dopaminergic therapies effectively alleviate the symptoms, albeit they do not revert the disease progression and result in significant adverse effects. Transplanting dopaminergic neurons derived from stem cells could restore dopa
The holotype (KUVP 1301) of Styxosaurus snowii—one of the earliest described elasmosaurid plesiosaurians—consists of a well-preserved cranium, mandible and articulated sequence of anterior–mid-series cervical vertebrae found in the lowermost Campanian strata of the Smoky Hill Chalk Member in the Niobrara Formation of Kansas, USA. This particular specimen has proven important for recent phylogenies
This study evaluates the impact of agricultural subsidies (CAP) on employment outside the agricultural sector. A side-effect of the decoupling reform in 2005 was that Sweden introduced a grassland support which caused a redistribution of payments among regions. This heterogeneity in transfers is used to identify the effects of government transfers on regional labour markets. The effect on employme
Background: While cognitive-behavioral therapy (CBT) is the gold-standard psychological treatment for major depression (MD), non-response and lacking stability of treatment gains are persistent issues. Potential factors influencing treatment outcome might be lifetime trauma history and possibly associated primarily prefrontal-cortex- and hippocampus-dependent cognitive alterations. Method: We inve
Background: Bariatric surgery is a standard treatment for severe obesity, but little is known about patients’ perceptions about the long-term impact of such surgery. Objective: The aim of this study was to explore patients’ experiences of living with a bariatric procedure for more than a decade. Setting: University hospital. Methods: At the 10-year follow-up after undergoing Roux-en-Y gastric bypa
Pond water is used in everyday life by many people in Bangladesh, however, without sufficient and reliable information regarding water quality and pollution status. For this reason, geospatial analysis and mapping of water quality indices such as metal (MI), contamination (Cd), and physicochemical water quality index (WQI) were assessed to improve the understanding of potential pollution sources.
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgi
In the philosophy of J. L. Schellenberg, “evolutionary religion” is a religious stance oriented towards the deep future. According to Schellenberg, the best form of evolutionary religion is non-doxastic faith in ultimism. I reject Schellenberg’s arguments for preferring ultimism and suggest that committing non-doxastically to traditional religion makes more sense from an evolutionary perspective.
We investigate how users on a prominent forum for white supremacists interpreted and framed two seminal events for the far-right in the U.S., the elections of Obama in 2008 and Trump in 2016. These cases precipitated dramatic shifts in the far-right alliance and conflict structure. We combine computational methods and qualitative analysis on a corpus of over ten million posts on Stormfront.org to
Integrated product development is a set of complex activities and its level of difficulty is additionally increased by the ever-changing business environment, primarily by functional associating of geographically dispersed human resources. The key resources for development are product developers, but it is questionable whether the existing systems are appropriate for the education of such professi
