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The exact mechanism of action of IVIg in the amelioration of immune thrombocytopenic purpura (ITP) is still unclear. Studies have suggested that IVIg may function through the regulation of cytokines, including interleukin-1 receptor antagonist (IL-1Ra), an inhibitor of phagocytosis. Using a mouse model relevant to ITP, we confirm an increase in mouse serum levels of IL-1Ra after exposure to IVIg,
Background: In collaboration with United European Gastroenterology, the working group on ‘Harmonizing diagnosis and treatment of chronic pancreatitis across Europe’ (HaPanEU) developed European guidelines for the management of chronic pancreatitis using an evidence-based approach. Methods: Recommendations of multidisciplinary review groups based on systematic literature reviews to answer predefine
This study presents the main features of the Swedish approach for resolving the banking crisis of 1991-93 by condensing them into seven policy lessons. These concern (1) the importance of political unity behind the resolution policy, (2) a government blanket guarantee of the financial obligations of the banking system, (3) swift policy action where acting early was more important than acting in e
In order to combat the effects of climate change, it is important to use a combination of solutions to achieve carbon neutrality as soon as possible. Carbon capture and sequestration is one such technology that can be used to significantly reduce the carbon footprint of many industrial plants. A mature technology for CO2 capture, amine-based post-combustion capture, is readily available today. How
The eyelids are susceptible to a number of skin cancers which are challenging to excise radically without sacrificing excessive healthy tissue. The way in which a tumor is delineated preoperatively has not changed significantly over the past century. The aims of the work presented in this thesis were to investigate two novel non-invasive techniques for diagnosing and delineating skin tumors.Extend
Rapporten behandlar ett projekt som utifrån samverkan undersökte möjligheterna att använda människors minnen och historia som utgångspunkt för att utveckla en plats, specifikt det hamnområde som omvandlas till området Oceanhamnen i Helsingborg genom utvecklingsprojektet H+. Människor med anknytning till hamnen intervjuades, arkivmaterial och annat samlades in. Materialet sammanställdes och blev ut
Health education materials such as flipbooks enhance learning and deliver key messages in a captivating mode. Validation of such materials is crucial to ensuring implementation fidelity. We conducted a study to achieve two objectives: (a) to develop two flipbooks, one each for adolescents and young married women (YMW); (b) to validate the flipbooks using five parameters, namely, content validity,
Background Frontotemporal dementia (FTD) is a pathologically heterogeneous neurodegenerative disorder associated usually with tau or TDP-43 pathology, although some phenotypes such as logopenic variant primary progressive aphasia are more commonly associated with Alzheimer's disease pathology. Currently, there are no biomarkers able to diagnose the underlying pathology during life. In this study,
Multi‐compartment T2 mapping has gained particular relevance for the study of myelin water in the brain. As a facilitator of rapid saltatory axonal signal transmission, myelin is a cornerstone indicator of white matter development and function. Regularized non‐negative least squares fitting of multi‐echo T2 data has been widely employed for the computation of the myelin water fraction (MWF), and t
This is a revised and extended version of my contribution to the Vega Symposium on Resurgent Nationalisms and Populist Politics in the Neoliberal Age, held at the Swedish Academy of Sciences, Stockholm, in April 2018. It is part of a Special Issue of Geografiska Annaler, Series B which also includes articles by Gillian Hart, Kanishka Goonewardena, and Manu Goswami. The article investigates how und
I kapitel 4 utforskar Gustav Hägg hur väl entreprenörskapsutbildningar fung- erar och varför vi överhuvudtaget ska satsa på utbildning i entreprenörskap. Kapitelförfattaren lyfter inledningsvis att entreprenören ofta associeras med enhör- ningen och att det inte sällan är framgångsrika individer som lyfts fram. Enligt Hägg är detta missvisande då entreprenören kommer i alla möjliga skepnader och fI kapitel 4 utforskar Gustav Hägg hur väl entreprenörskapsutbildningar fung- erar och varför vi överhuvudtaget ska satsa på utbildning i entreprenörskap. Kapitelförfattaren lyfter inledningsvis att entreprenören ofta associeras med enhör- ningen och att det inte sällan är framgångsrika individer som lyfts fram. Enligt Hägg är detta missvisande då entreprenören kommer i alla möjliga skepnader och f
The processes that led to the formation of the planetary bodies in the Solar system are still not fully understood. Using the results obtained with the comprehensive suite of instruments onboard the European Space Agency's Rosetta mission, we present evidence that comet 67P/Churyumov-Gerasimenko likely formed through the gentle gravitational collapse of a bound clump of mm-sized dust aggregates ('
An generalised engineering approach based on the analogy between mass and heat transfer is proposed to benchmark the shell-side mass transfer coefficient for axial flow in hollow fibre modules from low to moderate packing densities. The trends obtained by this approach are similar to those of correlations found in the literature and differences between the approaches are discussed. Furthermore,
Blood flow measurements in the ascending aorta and pulmonary artery from phase-contrast magnetic resonance images require accurate time-resolved vessel segmentation over the cardiac cycle. Current semi-automatic segmentation methods often involve time consuming manual correction, relying on user experience for accurate results. The purpose of this study was to develop a semi-automatic vessel segme
Measures for the reduction of electric energy loads for lighting have predominantly focussed on increasing the efficiency of lighting systems. This efficiency has now reached levels unthinkable a few decades ago. However, a focus on mere efficiency is physically limiting, and does not necessarily ensure that the anticipated energy savings actually materialise. This paper presents a literature surv
