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Improving the survival rate and quality of life of patients with acute and chronic hepatic dysfunction still represents a challenge. Cell-based therapeutic hepatocyte transplantation has great potential to serve as a temporary support and “bridge” prior to a donor organ becoming available, or even as therapy for replacing a compromised liver. In this review we describe potential applications of hu
As part of a European research project (FOOD-PCR), we developed a standardized and robust PCR detection assay specific for the three most frequently reported food-borne pathogenic Campylobacter species, C. jejuni, C. coli, and C. lari. Fifteen published and unpublished PCR primers targeting the 16S rRNA gene were tested in all possible pairwise combinations, as well as two published primers target
A new control strategy has been introduced for operating anaerobic digestion processes efficiently at high load. The control system includes a cascade controller embedded into a rule-based supervisory system based on extremum-seeking control. Three process parameters, considered to be the most realistic variables for monitoring of the bioprocess, were selected (pH, biogas production rate, and the
Mitogenic effects of the extracellular nucleotides ATP and UTP are mediated by P2Y(1), P2Y(2), and P2Y(4) receptors. However, it has not been possible to examine the highly expressed UDP-sensitive P2Y(6) receptor because of the lack of stable, selective agonists. In rat aorta smooth muscle cells (vascular smooth muscle cells; VSMC), UDP and UTP stimulated (3)H-labeled thymidine incorporation with
Background: The relationship between plasma markers of inflammation and the incidence of chronic obstructive pulmonary disease (COPD) is still unclear. This population-based study explored whether raised levels of five inflammation-sensitive plasma proteins (ISPs) predicted hospital admissions for COPD during 25 years of follow-up. Methods: Spirometric tests and measurements of five ISPs (fibrinog
This article sets out to describe and explain the events that led, in the summer of 1967, to political chaos and near civil war in many parts of China. It links the violence on the ground to statements and policies formulated at the highest levels of the CCP and sets out to show how and why Mao Zedong himself must bear direct personal responsibility for what stands out as one of the darkest chapte
BACKGROUND: The purpose of this study was to analyze the impact of stent-graft design and operator skills on outcomes after endovascular abdominal aortic aneurysm repair. STUDY DESIGN: One hundred sixty-four patients (mean age 71 years) underwent stent-graft repair. Patients were treated with four different types of stent-graft: first-generation (n = 58) and second-generation (n = 17) Ivancev-Malm
To analyze the role of the classical and alternative pathways of complement activation in the effector phase of arthritis, we have induced arthritis in C3- and factor B (FB)-deficient (C3(-/-) and FB-/-) DBA/1J mice using well-defined monoclonal IgG2b and IgG2a antibodies to type II collagen. In control DBA/1J mice, severe swelling of the joints, destruction of cartilage and erosion of bone develo
Abstract is not available
Popular Abstract in Swedish Kolhydrater är viktiga inte bara som bränsle och strukturgivande egenskaper, vilket var uppfattningen för 25 år sedan. De ingår även som en mycket viktig del i hur celler kommunicerar med varandra. Det har de senaste åren visat sig vara kolhydrater inblandade i en mängd signalering- och igenkänningsmekanismer. Några exempel: när bakterier angriper en cell är det oftast Artificial, amfiphilic, and biomimetic receptors soluble in water were synthesized via attaching polar amino acids to hydrophobic back-bones possessing a surface suitable for hydrophobic interactions. The hydrophobic back-bones chosen in this thesis were anthracene and dibenzobarrelene structures. A route to an efficient synthesis of a dibenzobarrelene backbone with two sets of orthogonal reactivi
This paper discusses spatial interventions as an important part of women’s struggles to improve their living conditions in poor urban areas. A case-study from San José, Costa Rica is the basis for the discussion. Women’s interventions are analyzed in three public places— a park, a playground and a community centre— through the concept of appropriation. The study shows that women’s interventions ha
Tests were done measuring resistivity and time domain induced polarisation using standard multi-core cable spreads and a special layout with separate cable spreads for transmitting current and measuring potentials. For both types of cables spreads both normal and reciprocal measurements were done in order to estimate the measurement errors. The tests were done along a planned tunnel stretch outsid
Investigations over two major tectonic zones in the Hallandsås Horst, Southern Sweden were carried out in connection with a railway tunnelling project. A combination of resistivity imaging, core drilling and geophysical logging was found to provide a good overview of the variation in rock quality and detailed information on the engineering geological characteristics and genesis of the strata. Resi
Borderline Personality Disorder (BPD) has largely been associated with self-harm and chronic suicidality, despite the fact that these behaviours comprise only one diagnostic criterion. Treatments for self-harm are mostly indicated for individuals with BPD. Emerging literature suggests that youth with histories of depression are at risk of both self-harm and completed suicide. For individuals with
Background: Complex I (CI or NADH:ubiquinone oxidoreductase) deficiency is the most frequent cause of mitochondrial respiratory chain defect. Successful attempts to rescue CI function by introducing an exogenous NADH dehydrogenase, such as the NDI1 from Saccharomyces cerevisiae (ScNDI1), have been reported although with drawbacks related to competition with CI. In contrast to ScNDI1, which is perm
