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Background: Alzheimer's disease (AD) is a neurodegenerative disorder caused by a complex interplay of various factors. However, a satisfactory cure for AD remains elusive. Pharmacological interventions based on drug targets are considered the most cost-effective therapeutic strategy. Therefore, it is paramount to search potential drug targets and drugs for AD. Objective: We aimed to provide novel
AIMS: The aim of this study was to identify and describe methods that physiotherapists use to evaluate the immediate effects of their interventions for infants in hospital with acute respiratory tract infections.METHODS: We constructed an anonymous digital survey to physiotherapists working with infants aged 0-24 months in Sweden. The survey was distributed by e-mail and posted on web pages for se
This paper forms part of a broader study on the design optimization of a high speed switched reluctance motor for automotive traction applications. Due to the high speed operation and resulting high electrical frequency, it is of extreme importance that the different loss components of this motor are accurately calculated. In this study, several effects are observed that influence the accurate mea
Publikationen sammanställer kunskap relevant för att utveckla och praktisera ledarskap i aktörsgemensamma sammanhang. Innehållet täcker centrala begrepp och beskriver olika organisatoriska miljöer som blir aktuella i samband med kriser och totalförsvar.
Anticancer drugs can be delivered more efficiently to tumor sites with fewer side effects by utilizing magnetic nanoparticles. In this research detailed examinations of the effect of polyethylene glycol (PEG) on microstructure, size distribution, morphology, magnetic performance and coating of cobalt ferrite nanoparticles (CFO) were conducted. CFO nanoparticles were functionalized by PEG under dif
Background: Patients with generalized social anxiety disorder (SAD) avoid various social situations and can be reluctant to engage in in vivo exposure therapy. Highly personalized practising can be required before patients are ready to perform in vivo exposure. Virtual reality-based therapy could be beneficial for this group.Aims: To assess the feasibility and potential effect of virtual reality-b
We have employed a new approach to quantify the amount fraction of nitrous oxide in a synthetic air matrix gas used to prepare high-accuracy reference materials of the same component. Until now, this was the largest contributor to the measurement uncertainty of nitrous oxide in air reference materials at atmospheric amount fractions (∼330 nmol mol-1), as identified in a recent international compar
Certain oxygenated compounds, called oxygenates, when blended with gasoline, have the ability to inhibit the occurrence of engine knock, thus helping improve spark-ignition engine efficiency. Similarly, oxygenates can also be added to diesel fuel to decrease the exhaust emissions—soot in particular—from diesel engines. Although ethanol and biodiesel have had widespread use as oxygenates for gasoli
This paper discusses the role of fundamental rights in the EU’s legislation on digitalisation, with a particular focus on the proposed Digital Services Act (DSA) and the Digital Markets Act (DMA). As the EU Charter of Fundamental Rights is receiving an increasingly prominent role in regulating the digital sphere in order to rectify the increasing challenges of a ‘wild West’ internet, the constitut
Men outnumber women as military drone operators, both in media narratives and in reality, as prominent Western militaries such as the US and the UK have far more men than women in their ranks. In recent years, Russia’s invasion of Ukraine has brought newfound attention to the use of drone warfare; specifically, how the media overwhelming spotlights male drone operators. However, portrayals of wome
BACKGROUND: Early palliative care provides better quality of life, increased prognostic awareness, and even improved survival for patients with advanced cancer but how the integrated care model achieves these outcomes has not been completely explained.METHODS: To better understand the clinical approach to early outpatient care from the clinicians' perspective, we conducted focus groups with the pa
OBJECTIVES: To correlate femoral neck Hounsfield units (HUs) measured on a computed tomography (CT) scan to dual-energy x-ray absorptiometry (DEXA) T-scores allowing evaluation of bone mineral density (BMD) over time after lower extremity trauma-related amputation.DESIGN: Retrospective cohort study.SETTING: United States military trauma referral center.PATIENTS: Military combat-related lower extre
Statistics reveal the concerning prevalence of mental health issues among Swedish public sector managers, highlighting the critical need for deeper insights into the relevance of social support in coping with work-related stress. This study aims to examine the relevance of various sources of social support for managers coping with work-related stress, an area relatively underexplored in public adm
A permanently available molecular-beam injection setup for controlled molecules (COMO) was installed and commissioned at the small quantum systems (SQS) instrument at the European x-ray free-electron laser (EuXFEL). A b-type electrostatic deflector allows for pure state-, size-, and isomer-selected samples of polar molecules and clusters. The source provides a rotationally cold (T ≈ 1 K) and dense
This paper discusses the interplay between acquisition and theory construction. It endeavors to show how a more direct and crucially bi-directional relationship between formal linguistic theory and the study of heritage language bilingualism can provide mutual benefit. It will be argued that data from acquisition—not exclusively but indeed especially from heritage language bilingualism—provide win
Influences of upstream wastewater treatment on the process combination of granular activated carbon (GAC) and ultraviolet (UV) disinfection were studied and the implications of this for wastewater reuse were assessed. GAC is an efficient chemical barrier but contributes little to the removal of indicator bacteria, and generally increases total bacteria concentrations, necessitating disinfection wi
A 1D imaging soft X-ray spectrometer installed on the small quantum systems (SQS) scientific instrument of the European XFEL is described. It uses movable cylindrical constant-line-spacing gratings in the Rowland configuration for energy dispersion in the vertical plane, and Wolter optics for simultaneous 1D imaging of the source in the horizontal plane. The soft X-ray fluorescence spectro-imaging
In this study, we present the initial results from a long-term initiative to develop a multi-millennial tree-ring width (TRW) chronology for subfossil oak (Quercus spp.) trees in South Scandinavia. We have constructed 40 TRW chronologies, primarily from oak trunks extracted from peatlands, archaeological sites, drainage ditches, and infrastructure projects, as well as some submerged material. The
