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Radiocarbon dating is the gold standard in archeology to estimate the age of skeletons, a key to studying their origins. Many published ancient genomes lack reliable and direct dates, which results in obscure and contradictory reports. We developed the temporal population structure (TPS), a DNA-based dating method for genomes ranging from the Late Mesolithic to today, and applied it to 3,591 ancie
We consider a numerical approximation of a linear quadratic control problem constrained by the stochastic heat equation with nonhomogeneous Neumann boundary conditions. This involves a combination of distributed and boundary control, as well as both distributed and boundary noise. We apply the finite element method for the spatial discretization and the linear implicit Euler method for the tempora
Background: Pancreatic ductal adenocarcinoma is a highly fatal malignancy. The aim was to identify preoperative factors for early mortality in up-front resectable patients following pancreatoduodenectomy (PD) and develop an early mortality risk score. Methods: Patients registered in the Swedish National Registry for Pancreatic and Periampullary Cancer were included. Relevant preoperative factors (
Knowledge of price formation in fisheries is important in understanding effects of fisheries regulations and the support or resistance to regulations from different stakeholders. This article studies how demand can be traced out using wind speed on a fishing trip. Wind speed is strongly correlated with the quantities of Norwegian lobster (Nephrops) available on the market. Using wind variables as
The ongoing war in Ukraine is associated with unprecedented radiological threats to the public in Ukraine and the neighboring countries. This calls for fundamental revision of the preparedness plans and established approaches to radiological monitoring of the populations affected by potential radiological emergencies. Dosimetric information will be needed for triage of victims and support to decis
In vitro digestion studies often use animal digestive enzyme extracts as substitutes of human gastric and pancreatic secretions. Pancreatin from porcine origin is thus commonly used to provide relevant pancreatic enzymes such as proteases, amylase and lipase. Rabbit gastric extracts (RGE) have been recently introduced to provide gastric lipase in addition to pepsin. Before preparing simulated gast
Thousands of barley (Hordeum vulgare L.) mutants have been isolated over the last century, and many are stored in gene banks across various countries. In the present work, we developed a pipeline to efficiently identify causal mutations in barley. The pipeline is also efficient for mutations located in centromeric regions. Through bulked segregant analyses using whole genome sequencing of pooled F
Stimuli-responsive polymer nanoparticles were synthesized by surfactant-free dispersion polymerization of styrene and 2-(dimethylamino)ethyl methacrylate (DMAEMA) in three different contents of divinylbenzene intraparticle crosslinking agent. Incorporation of the hydrophilic DMAEMA comonomer during the polymerization yielded pH-responsive nanogels with a higher size than the polystyrene nanopartic
Background: Alzheimer's disease (AD) is a neurodegenerative disorder caused by a complex interplay of various factors. However, a satisfactory cure for AD remains elusive. Pharmacological interventions based on drug targets are considered the most cost-effective therapeutic strategy. Therefore, it is paramount to search potential drug targets and drugs for AD. Objective: We aimed to provide novel
AIMS: The aim of this study was to identify and describe methods that physiotherapists use to evaluate the immediate effects of their interventions for infants in hospital with acute respiratory tract infections.METHODS: We constructed an anonymous digital survey to physiotherapists working with infants aged 0-24 months in Sweden. The survey was distributed by e-mail and posted on web pages for se
This paper forms part of a broader study on the design optimization of a high speed switched reluctance motor for automotive traction applications. Due to the high speed operation and resulting high electrical frequency, it is of extreme importance that the different loss components of this motor are accurately calculated. In this study, several effects are observed that influence the accurate mea
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Anticancer drugs can be delivered more efficiently to tumor sites with fewer side effects by utilizing magnetic nanoparticles. In this research detailed examinations of the effect of polyethylene glycol (PEG) on microstructure, size distribution, morphology, magnetic performance and coating of cobalt ferrite nanoparticles (CFO) were conducted. CFO nanoparticles were functionalized by PEG under dif
Background: Patients with generalized social anxiety disorder (SAD) avoid various social situations and can be reluctant to engage in in vivo exposure therapy. Highly personalized practising can be required before patients are ready to perform in vivo exposure. Virtual reality-based therapy could be beneficial for this group.Aims: To assess the feasibility and potential effect of virtual reality-b
We have employed a new approach to quantify the amount fraction of nitrous oxide in a synthetic air matrix gas used to prepare high-accuracy reference materials of the same component. Until now, this was the largest contributor to the measurement uncertainty of nitrous oxide in air reference materials at atmospheric amount fractions (∼330 nmol mol-1), as identified in a recent international compar
