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Objective: Classification criteria for early-stage symptomatic knee osteoarthritis (EsSKOA) should discriminate individuals with EsSKOA from those with other causes of knee symptoms. We sought to identify conditions in the differential diagnosis of EsSKOA in adults with knee symptoms. Design: We conducted an online survey of clinicians. Those consulting monthly on at least five people with undiagn

BACKGROUND: Selective glomerular hypofiltration syndrome (SGHS), formerly shrunken pore syndrome, an emerging marker of glomerular dysfunction, is associated with worsened prognosis in cardiovascular disease, but its role in kidney failure remains underexplored. Osteopontin (OPN) is associated with worsening kidney function and prognosis in chronic kidney disease.PURPOSE: To explore if increased l

Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation. We report a genome-wide association study and multi-trait analysis of DCM (14,256 cases) and three left ventricular traits (36,203 UK Biobank participants). We identified 80 genomic risk loci and prioritized 62 putative effector genes, including several with rare variant DCM associations (MAP3K7, NEDD4L a

Controlling the streaming flow in acoustically actuated microchannels enables the targeted motion of suspended micro-objects. This can offer novel approaches for rare cell studies or cell sorting in medicine or basic biology. In this work, we utilize the temperature dependence of the acoustic body force, which originates from the interaction of an acoustic field with gradients in compressibility o

Chaperone proteins are essential for maintaining proteostasis. Their main role is to assist with the folding of other proteins and to prevent the aggregation of misfolded proteins. The molecular chaperone DNAJB6b efficiently suppresses amyloid formation of several peptides. This activity may rely on the same physicochemical properties as those driving chaperone self-assembly into large micellar-li

The unprecedented x-ray flux density provided by modern x-ray sources offers new spatiotemporal possibilities for x-ray imaging of fast dynamic processes. Approaches to exploit such possibilities often result in either (i) a limited number of projections or spatial information due to limited scanning speed, as in time-resolved tomography, or (ii) a limited number of time points, as in stroboscopic

Purpose: The Paleolithic Diet Fraction (PDF) estimates the proportion of absolute dietary intake derived from food groups included in the Paleolithic diet. In the Malmö Diet and Cancer Study (MDCS), higher PDF and lower systemic low-grade chronic inflammation (SLGCI) have been associated with lower cardiometabolic morbidity and mortality. We examined associations between PDF and SLGCI in the MDCS.

Migratory birds have evolved a multitude of physiological and behavioural adaptations to reach their population-specific wintering areas during their first migration. The endogenous program encodes distance, direction and fuelling, and involves species-specific adaptations leading naïve migratory birds along highly diverse routes. While daylength has been extensively studied in relation to the ons

Microsoft Word - GEOA73.doc Litteraturlista för GEOA73 Dinosauriernas värld, 7,5 högskolepoäng (The Age of the Dinosaurs, 7.5 ECTS credits) Fastställd av institutionsstyrelsen 2009-05-04 Författare & titel (ev. tidskrift, serie, etc.) B,I,L (*) Sidor som skall läsas, Anmärkningar, (**) Fastovsky, D. E. & Weishampel, D. B. 2009: Dinosaurs – A Concise Natural History. Cambridge University Press. 379

https://www.geologi.lu.se/sites/geologi.lu.se/files/geoa73-kursplan.pdf - 2026-05-23

Microsoft Word - Course assessment GEON03 2016 Course evaluation GEON03 Quaternary Climate and Glaciation History Spring term 2016 THE EVALUATION BELOW AND THE CONCLUDING ASSESSMENT ARE BASED ON FOUR ANSWERS (OUT OF FIVE REGISTERED STUDENTS ON THE COURSE) NOTE: THE EVALUATION WAS PERFORMED BEFORE THE CONCLUDING EXCURSION THROUGH S. SWEDEN NOTE GRADING SCALE FOR ALL QUESTIONS: 1 = strongly disagree

https://www.geology.lu.se/sites/geology.lu.se/files/geon03_course_assessment_2016.pdf - 2026-05-23

BackgroundResearch involving current and future generations of older adults in the design of smart home technology (SHT) is scarce. In this study, current and future generations of older adults, professionals, and researchers together sought to identify user needs and aspirations for and related to SHT. The aim was to co-produce prioritized ideas for SHT solutions to support engagement in everyday

Antimicrobial peptides are widely investigated in the literature, but their mechanism of action and effects on lipid membranes are not completely understood from a physicochemical perspective. In this study, we employed a bioinspired mastoparan from wasp venom, mast-MO, and characterized its interactions with model lipid membranes, either as a supported lipid bilayer or as free-standing vesicles i

Particle induced oxidative stress is a probable pathway for many of the detrimental health-effects caused by particulate matter (PM). Recent studies on the exposure to oxidative potential (OP) in ambient fine and coarse PM suggest that anthropogenic particle pollutants, especially vehicular wear, anthropogenic primary and secondary organic aerosols (SOA) are more toxic on mass basis and more relev

Ferroelectricity in Hf0.5Zr0.5O2 (HZO) originates from a polymorphic landscape where the metastable orthorhombic phase competes with monoclinic and tetragonal forms, making functional properties highly sensitive to structural instability. Recent strategies have exploited ionic-vacancy mechanisms, either through redox interactions with the environment or by employing ferroionic heterostructures, to

Selenium (Se), an essential trace element, is linked to poor prognosis in heart failure (HF) and kidney disease. Se deficiency (serum Se < 70 μg/L) has been associated with increased cardiovascular mortality. Selenoprotein P (SELENOP), the main Se transporter, reflects bioavailable Se. Selective glomerular hypofiltration syndrome (SGHS), defined by a cystatin C-based eGFR < 0.7 of creatinine-based

Aim: This study evaluates the health effects of plant-based dairy alternatives in healthy individuals and those with Inflammatory Bowel Disease (IBD). Specifically, it investigates whether replacing one daily meal with a plant-based alternative has a positive impact on intestinal microbiota composition and gut health. It also investigates whether the effect of probiotic bacteria in yogurt depends

Ambient pressure X-ray photoelectron spectroscopy (APXPS) has emerged as an important technique for investigating surface and interface chemistry under realistic conditions, overcoming the limitations of conventional XPS restricted to ultrahigh vacuum. This review highlights the capabilities and scientific impact of APXPS at the MAX IV Laboratory, the world’s first fourth-generation synchrotron li

AIMS: The COVID-19 pandemic had substantial impacts on mortality and morbidity, even after the rollout of vaccinations. These impacts however, varied considerably across regions. We examined regional disparities in COVID-19 mortality and hospitalizations among older people in Sweden from January 2021 to August 2023 and assessed the role of vaccination coverage in shaping these disparities.METHODS: