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Advancing 90-day mortality and anastomotic leakage predictions after oesophagectomy for cancer using Explainable Artificial Intelligence
Introduction: Oesophageal resection carries significant morbidity and mortality. Artificial intelligence (AI) advances in medical research enable enhanced predictions, flexibility, and interpretability, especially for complex interactions and nonlinear relationships. Material and methods: We used a register-based case-control design nested within prospectively collected data from the Swedish Natio
Buried Interface evolution of 2D/3D heterojunction inverted perovskites solar cells
The instability of perovskite interfaces caused by interfacial defects and heterojunction evolution hinders the realization of long-term stable inverse perovskite solar cells (IPSCs). This work reports a strategy for the study of heterojunction evolution, the effects of buried interface and carrier dynamics on the stability of perovskite films and devices in 2D/3D heterojunctions. The emphasis is
Growth, structure, and morphology of ultra-thin tin oxide phases forming on Pt3Sn(111) single crystals upon exposure to oxygen
Here we report an investigation of ultrathin tin oxide films on Pt3Sn(111) using low-energy electron microscopy (LEEM), microspot low-energy electron diffraction (μ-LEED), scanning tunneling microscopy (STM), surface X-ray diffraction (SXRD), and high-resolution X-ray photoelectron spectroscopy (XPS). Oxidation at ∼390–410 °C produces triangular, two-dimensional oxide islands that nucleate rapidly
The Meaning of Surveillance in Women With a Hereditary Risk of Breast Cancer: A Hermeneutic Phenomenological Study
AimTo explore the meaning of lived experiences of women with a hereditary risk of breast cancer who participate in surveillance of their breasts with magnetic resonance imaging.DesignHermeneutic phenomenology.MethodsInterviews on two occasions were made with 14 women in the surveillance programme. The verbatim transcripts were analysed according to van Manen. The analysis was an insightful iterati
Passive film evolution on Ni-Cr-Mo alloys in acidic chloride solution during anodic polarization
Passivity arises from spontaneous formation of a thin protective passive film (oxide/hydroxide layer) on the metal surface, and the stability of passive film is of great importance for corrosion resistance. This study investigates the formation, stability, and transpassive dissolution of passive films on two Ni-based alloys, Alloy 625 and Alloy 59, in acidified NaCl solution, by combining in situ
Screening for iron deficiency in young women : the predictive validity of a five-item screening instrument (IRON-5)
BACKGROUND: Iron deficiency is the most common micronutrient deficiency worldwide, negatively affecting quality of life and health. Young women are at particularly high risk due to increased iron demands during growth, menstrual blood losses, and dietary habits. There are no official guidelines recommending screening for iron deficiency in healthy young women. This study aimed to develop a screeni
Raman spectroscopy in microfluidic chips reveals hyphal scale stress-associated metabolic responses in filamentous soil fungi
Understanding metabolic processes of soil fungi is essential for elucidating their ecological roles in biogeochemical cycles and responses to emergent environmental stressors. Here, we demonstrate the potential of using stable isotope probing Raman (SIP-Raman) microspectroscopy in microfluidics technology-based soil chips to trace glucose metabolism rates and stress responses in laboratory grown f
Experimental benchmarking of dielectric models for simulating the localized surface plasmon resonance in Au-Ag alloy nanospheres
The optical response of gold-silver (Au-Ag) alloy nanoparticles is strongly influenced by their localized surface plasmon resonance (LSPR), which can be tuned by varying the particle composition. Accurate simulation of LSPR, often performed using Mie theory, critically depends on the choice of dielectric function, yet available datasets for gold, silver, and their alloys vary widely. In this work,
TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques
Rupture of unstable atherosclerotic plaques is a major cause of mortality. Endothelial-to-mesenchymal transition associates with advanced atherosclerotic plaques and contributes to plaque progression. We examined the role of Twist1, a transcription factor that drives endothelial-to-mesenchymal transition, in plaque progression by inducible deletion from endothelial cells in hypercholesterolemic mi
Terahertz Magnetic-Resonance Mueller Matrix Ellipsometry
We report a radical extension of magnetic-resonance spectroscopy to the Terahertz (THz) spectral range by complete polarization-resolved measurement of the linear electromagnetic response of nuclear and electron spin associated magnetic resonance using principles of ellipsometry at high magnetic fields. This new method permits us to accurately test existing models and leads to discovery of new phy
Population-level analysis of glycoprotein glycoforms
The structure and function of many proteins are regulated post-translationally through glycan attachment. These glycans, assembled via competing enzymatic reactions, generate diverse glycoform populations - variants sharing a protein backbone but differing in glycan structures. While current analyses often focus on individual glycoforms, we demonstrate that population-level glycoform analysis - in
Evolution of the below-bandgap anisotropic refractive indices and dielectric functions of β-(AlxGa1− x)2O3 (0 < x < 0.25) determined by generalized spectroscopic ellipsometry
We determine the composition dependence of the below-bandgap anisotropic refractive indices and dielectric functions of β-(AlxGa1−x )2O3 for x up to 25% Al. We use Mueller matrix generalized spectroscopic ellipsometry and investigate a set of high quality single crystalline bulk (x = 0 %, 5 %, 10 %, 15 %, 20 %, 25 %) and thin film (4.6%, 9.7%, 12%, 15%, 16.3%, 21%) samples grown by the Czochralski
Neuromuscular adaptation and postural muscle activity patterns during visual virtual reality stimulation : age-related differences between young and older adults
Vision provides important sensory input to postural control. Medical conditions and aging affect sensory—Central Nervous System (CNS) interactions, causing mismatches. Virtual Reality (VR) may address these by promoting recalibration from vision to other systems. Twenty-eight young adults (17 males, mean age 25.3 years) and 25 older adults (14 males, mean age 74.8 years) were included. Electromyog
Vacancy-Mediated NiAs–Ni2In-Type Intermetallic Phases : Ni1+δ(In/Sb)
Ni1+δSn (δ = 0.2, 0.4) and Ni1+δ(In/Sb) (δ = 0.1–0.5) (NiAs/Ni2In type) were synthesized, and their crystal structures were studied in this report. In Ni1+δ(In/Sb), the excess nickel atoms (δ = 0.1–0.5) occupy the vacant trigonal bipyramidal interstitial sites in the NiAs-type structural arrangement, leading to the evolution of a fully disordered to ordered superstructure through a series of incom
The role of gene-environment interactions in endocrine-sensitive life stages for shaping mental health : focus on the RE-MEND project
The number of people seeking help for mental illness is increasing across all ages, creating a major burden for individuals, families, and the society. While personalized medicine is advancing in other fields, diagnosis and treatment of mental disorders remain largely symptom-based and fail to capture individual, sex, and gender differences in risk, manifestation, and treatment response. Early sig
Self-Report Tool for Identification of Individuals With Coronary Atherosclerosis : The Swedish CardioPulmonary BioImage Study
BACKGROUND: Coronary atherosclerosis detected by imaging is a marker of elevated cardiovascular risk. However, imaging involves large resources and exposure to radiation. The aim was, therefore, to test whether nonimaging data, specifically data that can be self-reported, could be used to identify individuals with moderate to severe coronary atherosclerosis.METHODS AND RESULTS: We used data from t
Circulating lung-cancer-related non-coding RNAs are associated with occupational exposure to hexavalent chromium - A cross-sectional study within the SafeChrom project
BACKGROUND: Hexavalent chromium (Cr(Ⅵ)) is classified as a group 1 human carcinogen and increases the risk of lung cancer. Non-coding RNAs (ncRNAs) have key regulatory roles in lung cancer, but less is known about their relation to Cr(Ⅵ) exposure.OBJECTIVES: We aimed to 1) measure the expression of lung cancer-related circulating ncRNAs in exposed workers and controls; 2) assess associations betwe
Experimental exploration of potassium compounds in the vicinity of a burning biomass pellet : From near-surface to downstream
The concentrations of gas-phase potassium hydroxide (KOH), potassium chloride (KCl) and atomic potassium (K(g)) were quantitatively measured from the near-surface to downstream area of burning pinewood pellets by a newly developed photofragmentation tunable diode laser absorption spectroscopy (PF-TDLAS) technique to reveal the original form of the released potassium. The novel arrangement of the P
ADAM-17 Activity and Its Relation to ACE2 : Implications for Severe COVID-19
There is a lack of studies aiming to assess cellular a disintegrin and metalloproteinase-17 (ADAM-17) activity in COVID-19 patients and the eventual associations with the shedding of membrane-bound angiotensin-converting enzyme 2 (mACE2). In addition, studies that investigate the relationship between ACE2 and ADAM-17 gene expressions in organs infected by SARS-CoV-2 are lacking. We used data from
