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Background: Cardiovascular autonomic dysfunction is a major complication in a large proportion of patients with long coronavirus disease (LC). As one of the most typical phenotypes of cardiovascular autonomic dysfunction, postural orthostatic tachycardia syndrome (POTS) is commonly observed as a sequelae of coronavirus disease infection. Objective: This study aimed to develop and test a 24-hour el
Women have always played a central role in smallholder agriculture in many farming systems of the Global South. However, they have had, and still have, low access to agricultural information, and even less ability to enact on training or advice received, in comparison to male farmers. The paper investigates what is needed for female smallholders to better benefit from agricultural advice and train
Understanding the processes that drive phenotypic diversification and underpin speciation is key to elucidating how biodiversity has evolved. Although these processes have been studied across a wide array of clades, adaptive radiations (ARs), which are systems with multiple closely related species and broad phenotypic diversity, have been particularly fruitful for teasing apart the factors that dr
A crystallogenesis study of human transthyretin using the counter-diffusion method is described as an alternative to conventional convective vapour diffusion and batch approaches for protein crystallization. The X-ray diffraction results show systematic trends that exhibit unique patterns of crystallization and high crystal quality as well as a remarkable degree of coherence within extended crysta
INTRODUCTION: Behavioral and psychological symptoms of dementia (BPSD) are a common driver of suffering and high care needs. We describe the Swedish BPSD registry, founded in 2010 to develop an evidence base for quality improvement in the care of patients with BPSD. Further, we illustrate the potential of the registry by evaluating how individual BPSD affects mortality. METHODS: The registry provi
In several circumstances, a level-three automated vehicle cannot continue driving in an automated driving mode and requests a human driver to take over. In this study, a series of experiments to examine how to provide a TOR was conducted. First, for forty-one persons, a HUD icon, earcon, seat vibration, and combinations were compared. The results indicated that the HUD icon-earcon and HUD icon-sea
E-poster, 2-minute presentation Statement of Problem Self-generated mobility, defined as the capacity for independent movement, plays a critical role in early childhood development. Limited mobility, often associated with conditions like cerebral palsy or muscular dystrophy, poses significant developmental delays, particularly impacting physical, social, and cognitive growth. Description of the Co
Avgöra fas i LärandeProcessen (ALP): ett universellt verktyg för bedömning och främjande av aktivitetsutförande och verktygsanvändning. Det universella ALP-verktyget kan tillämpas med barn och vuxna, oberoende av deras förmågor, diagnos, funktionsnedsättningar eller i vilka situationer de utför aktiviteter eller verktygsanvändning. Detta innebär att arbetsterapeuter kan använda det universella ALP
Galectins are a family of carbohydrate-recognising proteins involved in regulation of cell adhesion and cell signaling, leading to roles in e.g. cancer progression, fibrosis, and ulcerative colitis. Glycomimetic galectin inhibitors based on different molecular scaffolds are known and have demonstrated effects from cell experiments to the clinic. Presented here is the synthesis and evaluation of 3-
The Schöningen 13II-4 archaeological site in Germany holds title to the most complete Paleolithic wooden hunting spears ever discovered, yet its age has never been properly settled. Initial estimates placed the site at around 400,000 years; this age was later revised to roughly 300,000 years. Here, we report age estimates for the “Spear Horizon” based on amino acid geochronology of fossils obtaine
Introduction Fatigue and altered cognitive capacity are common symptoms following cirrhosis. Patients consider information about cirrhosis difficult to understand. Health literacy levels vary among persons with chronic illnesses, which can hamper participation in and adaptation to treatment, potential restrictions and recommendations. Limited health literacy might also lead to decreased autonomy.
Combined density functional theory (DFT) and X-ray standing wave (XSW) studies have previously provided evidence for the preferential adoption of an inverted conformation of 2H-TPP on Cu(111) in contrast to the saddle conformation usually favored by porphyrin molecules adsorbed on metals. We experimentally demonstrate, via X-ray photoelectron spectroscopy (XPS) analysis, that the binding energies
Background/Objectives: Antibiotic resistance presents an urgent public health threat. By developing a streamlined and effective method for studying bacteriophage induction, this research marks a step further in understanding how antibiotic-resistant genes might spread across different environments. This knowledge is essential for creating strategies to reduce the spread of antimicrobial resistan
On March 30, 2022, Inno4Vac, a public-private partnership funded by the IMI2/EU/EFPIA Joint Undertaking (IMI2 JU), organised a hybrid workshop, titled “Regulatory Dialogue for Road Maps of Implementation of New Tools in Chemistry, Manufacturing, and Controls Dossiers.” This event brought together modellers, regulatory experts, and academic and industry professionals specialising in vaccine process
Density functional theory (DFT) thermochemistry of 3d transition-metal complexes is well-known to be sensitive to the amount of exact Hartree-Fock exchange incorporated into the exchange-correlation functional. For example, relative energies of different protonation states of iron-sulfur complexes may vary by hundreds of kJ/mol among different DFT methods. In the present study, we examine the rela
This paper reports results from an exploratory experimental study (N = 181) comparing an effort based public good game to a standard public good game — each presented in a gain and a loss frame. The data show lower average contributions and more free-riders in the effort treatments, with the most notable effect showing for men in the loss frame (comparing standard vs. effort, contributions drop fr
False lumen management of chronic aortic dissections has evolved during the past decade. Thoracic endovascular aortic repair (TEVAR) continues to be the mainstay of endovascular dissection treatment and relies on the adequate sealing of the proximal entry tear. However, TEVAR alone often fails to achieve aortic remodeling due to persistent distal retrograde perfusion of the false lumen with contin
Automated sorption balances are widely used for characterizing the interaction of water vapor with hygroscopic materials. This paper is part of an interlaboratory study investigating the stability and performance of automated sorption balances. A previous paper in this study investigated the mass, temperature, and relative humidity (RH) stability of automated sorption balances by looking at the ma
