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Strain-stress relationships for physical properties are of interest for heteroepitaxial material systems, where strain and stress are inherent due to thermal expansion and lattice mismatch. We report linear perturbation theory strain and stress relationships for optical phonon modes in monoclinic crystals for strain and stress situations which maintain the monoclinic symmetry of the crystal. By us
The Amazonian Craton is host to one of Earth’s largest Proterozoic silicic large igneous provinces (SLIPs), the Orocaima SLIP (ca. 1.98 Ga). Nevertheless, the mechanism(s) responsible for this large-flux felsic magmatic event and its relationships with regional tectonics and/or mantle processes remain debated. New geochronologic and geochemical results from multiple mafic dike swarms in the Amazon
BackgroundAmyloid-β peptides (Aβ) applied to Alzheimer's disease (AD) brain bind to amyloid plaques (APs) and this binding is saturable. Meanwhile, anti-immunoglobulin G (IgG) antibodies label APs. Considering the saturable binding of Aβ to APs and the localization of IgGs in APs, specific binding proteins (BPs) for the applied Aβ could be anti-Aβ IgG antibodies (anti-AβAbs) in APs.ObjectiveOur ob
The complexity of modern healthcare continues to evolve, emphasizing the need for comprehensive collaboration among professionals from diverse backgrounds, patients, and their families to integrate care. Multidisciplinary team meetings (MDTMs) have emerged as an opportunity to advance interprofessional collaborative practice. However, despite their growing prevalence in clinical and educational co
Knee osteoarthritis (OA) and obesity are closely linked, with obesity being the primary risk factor for OA. This study used the medial meniscus of sows (250 kg, 4–6 years old) as a model for spontaneous OA, comparing them to lighter pigs (110 kg, 7–8 months old). The joints were collected according to the 3Rs principles (Replacement, Reduction and Refinement) and compared using macroscopic and mic
Li-rich nickel cobalt manganese oxides (LNCM) cathode with full gradient compounds is prepared by using an ethanol assisted co-precipitation method. The rationally designed procedure involves gradient distributions of transition-metal ions, in which the Ni content increases continuously, Mn content decreases gradually and Co keeps at a low level. The employing ethanol during the synthesis adjusts
In Nordic countries, demand response (DR) programs are critical for enhancing energy flexibility and reducing peak electricity consumption in buildings and industry. Accurate short-term demand forecasting is essential to support these programs, especially in the context of cities with varying levels of data availability. This paper compares three different forecasting approaches for hourly electri
The Galactic center and inner disk of the Milky Way contain complex stellar populations obscured by heavy dust extinction. To study their chemical composition, high-resolution near-infrared (near-IR) spectroscopy is necessary. Expanding the set of elements measurable in the near-IR, especially neutron-capture elements, improves our ability to trace nucleosynthesis and Galactic chemical evolution.
In humans, a well-developed serotonin system is localized to the pancreatic islets while being absent in exocrine pancreas. Assessment of pancreatic serotonin biosynthesis could therefore be used to estimate the human endocrine pancreas. Proof of concept was tested in a prospective clinical trial by comparisons of type 1 diabetic (T1D) patients, with extensive reduction of β-cells, with healthy vo
Diabetic kidney disease (DKD) is a health burden that lacks specific and early diagnostic biomarkers. For their discovery, we sequenced urinary extracellular vesicle miRNAs in a type 1 diabetes cohort of males with and without DKD. The results were replicated by sequencing or qPCR in two independent cohorts and six published datasets, including type 1 and 2 diabetes, and both sexes. We also valida
Jorunn Joiner and Mari Komnæs also employ digital tools, albeit other ones, to shed light on the interaction between narratives of exceptionalism, travel, and place. In ‘Mapping Nordic Exceptionalism with GIS: The Odin Migration Theory and the Search for a Northern Heritage’, they use digital mapping tools to visualise the journeys of two travellers from different centuries in their search for a N
Electrospun nanofiber membranes (ENMs) with unique porous 3D network structure exhibit properties such as high porosity and surface area, fine-tuned surface functionality and uniform pore sizes. This makes them candidates for water/wastewater applications with excellent flow. This study focuses on the fabrication of polymeric and composite ENMs from polyacrylonitrile (PAN) and nanoclay (NC) and th
The question of the legal permissibility of heritable gene editing techniques is unsettled. The international consensus opposes clinical research and applications involving germline modifications. Building on previous work, this paper examines how international human rights law, particularly human right to science standards, can inform the regulation of this controversial advancement. We present t
Abstract: Diffusion-weighted imaging (DWI) offers critical insights into tissue microstructure through the assessment of water molecule random displacements and plays a central role in the assessment of neoplastic and non-neoplastic diseases. To successfully implement and use DWI in clinical practice, guidelines for acquisition, interpretation of image contrast and of artefacts should be followed,
Robotic systems often face execution failures due to unexpected obstacles, sensor errors, or environmental changes. Traditional failure recovery methods rely on predefined strategies or human intervention, making them less adaptable. This paper presents a unified failure recovery framework that combines Vision-Language Models (VLMs), a reactive planner, and Behavior Trees (BTs) to enable real-time
Robotic systems often face execution failures due to unexpected obstacles, sensor errors, or environmental changes. Traditional failure recovery methods rely on predefined strategies or human intervention, making them less adaptable. This paper presents a unified failure recovery framework that combines Vision-Language Models (VLMs), a reactive planner, and Behavior Trees (BTs) to enable real-time
N1-methyladenine (m1A), a modification of transcripts, regulates mRNA structure and translation efficiency. In a recent issue of Nature, Sun et al. reported that m1A in CAG repeat RNA contributes to CAG repeat expansion-induced neurodegeneration in Caenorhabditis elegans and Drosophila through enhancing the ability of endogenous TDP-43 to partition into stress granules mediated by m1A. The study i
The electrification of long-haul freight transport is essential for reducing emissions and achieving sustainable mobility. However, battery-electric trucks (BETs) face significant barriers, including limited range, high battery weight, and prolonged charging times, which hinder their widespread adoption for long-distance travel. Electric Road Systems (ERS) offer a compelling solution by providing
