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No generally accepted definition of osteoarthritis exists. Traditionally, the diagnosis is obtained by radiographic examination but different definitions are used for different purposes. Since no causal treatment exists, treatment is aiming at reducing symptoms and improving function. The correlation between radiographic features of osteoarthritis and symptoms is poor. Thus, it is recommended that
We have studied the use of complimentary alternative medicine (CAM) among 233 consecutive breast cancer patients operated on at the Lund University Hospital, Sweden between 2002 and 2004. Questionnaires were administered preoperatively (n = 233), and again 3-6 months post-operatively (n = 167) and one year after surgery (n = 88). At baseline, 14,5% used CAM, 3-6 months post-operatively 14,4% used Bruket av naturläkemedel och andra faktorer som kan interagera med behandling av bröstcancer kartläggs i en pågående studie hos bröstcancerpatienter i Lund; i artikeln redovisas basdata för 233 patienter. Vid inskrivningen använde totalt 14,5 procent av patienterna naturläkemedel, vid 1-årskontrollen 18,2 procent. Sammanlagt 35 olika preparat användes, varav soja och övriga fytoöstrogener, vitlök,
A scintillating fibre tracker is proposed to measure elastic proton scattering at very small angles in the ATLAS experiment at CERN. The tracker will be located in so-called Roman Pot units at a distance of 240 m on each side of the ATLAS interaction point. An initial validation of the design choices was achieved in a beam test at DESY in a relatively low energy electron beam and using slow off-th
We showed earlier that over-expression of protein kinase C (PKC) epsilon induces neurite outgrowth. The effect is mediated by a region (PKC epsilon PSC1V3) encompassing the pseudosubstrate, the two C1 domains and part of the V3 region, and is independent of the catalytic activity of the enzyme. In this region, residues immediately N-terminal of the C1b domain are crucial for neurite outgrowth. How
BACKGROUND: Peripheral blood progenitor cells (PBPCs) can be collected on various cell separators. Two leukapheresis programs (LP-MNC and LP-PBSC-Lym) were evaluated for computerized collection of PBPCs on a new cell separator. STUDY DESIGN AND METHODS: Leukapheresis assisted by the LP-MNC or LP-PBSC-Lym software was performed for the harvesting of PBPCs in 52 oncology patients after chemotherapy
A general model for pressure drop calculations in siphons and riser tubes has been developed. The model takes into account different physical flow phenomena such as the inlet pressure drop and the pressure drop in the tube. For each phenomenon, we applied theory and established correlations to calculate the separate accelerational, frictional, gravitational, and centrifugal pressure drops. Model r
Background and Purpose-A low risk of recurrent stroke and death after lacunar infarction has previously been reported, but follow-up has been limited to less than or equal to5 years. Methods-One hundred eighty patients with pure motor stroke, collected between 1983 and 1986 from a hospital-based stroke registry, were followed up until at least 10 years after the index stroke. Two patients were los
Developing a reliable and quantitative assessment of the potential virulence of a malignancy has been a long-standing goal in clinical cytometry. DNA histogram analysis provides valuable information on the cycling activity of a tumor population through S-phase estimates; it also identifies nondiploid populations, a possible indicator of genetic instability and subsequent predisposition to metastas
Background: The European Molecular Genetics Quality Network (EMQN) was formed in order to improve external quality assessment for molecular genetic testing in Europe. From 1999 to 2002 it received funding from the European Union under the Standards, Measurement and Testing programme (contract no. SMT4-CT98-7515). Since then, its maintenance has been supported through subscription of the participan
We investigated if low level laser therapy (LLLT) of the joint capsule can reduce pain in chronic joint disorders. A literature search identified 88 randomised controlled trials, of which 20 trials included patients with chronic joint disorders. Six trials were excluded for not irradiating the joint capsule. Three trials used doses lower than a dose range nominated a priori for reducing inflammati
Background: Tibial osteotomy is a treatment for younger and/or physically active patients suffering from uni-compartmental knee osteoarthritis. The open wedge osteotomy by the hemicallotasis technique includes the use of external fixation. The use of external fixation has several advantages, as early mobilization and the opportunity for optimal correction. However, the hemicallotasis technique has
BACKGROUND: Yeast and bacteria elicit arachidonate release in macrophages, leading to the formation of leukotrienes and prostaglandins, important mediators of inflammation. Receptors recognising various microbes have been identified, but the signalling pathways are not entirely understood. Cytosolic phospholipase A2 is a major down-stream target and this enzyme is regulated by both phosphorylation
Halomonas boliviensis LC1 is able to accumulate poly(beta-hydroxybutyrate) (PHB) under conditions of excess carbon source and depletion of essential nutrients. This study was aimed at an efficient production of PHB by growing H. boliviensis to high cell concentrations in batch cultures. The effect of ammonium, phosphate, and yeast extract concentrations on cell concentration [cell dry weight (CDW)
Rabbits skin folds were placed in plexiglass chambers enabling control of the skin fold temperature during cuff compression (200 mmHg) for 4 hours. In 10 animals the skin folds were kept at 36 degrees C - in another 10 animals the skin fold temperature was lowered to 10 degrees C. To quantitate the skin injury caused by the pressure ischemia a standardized wound was made, and immediately closed, a
Popular Abstract in Swedish Denna undersökning inventerar beståndet av beteckningar för EGENDOM I ALLMÄNHET och för MOBIL och IMMOBIL EGENDOM i de regionala medeltida nordiska lagarna (dvs. de danska och svenska landskapslagarna, de norska lagtingslagarna samt den isländska Grágás). Materialet analyseras språkgeografiskt med avsikten att skapa en relativ termkronologi. En grovanalys visar attféThis study investigates the stock of words for PROPERTY IN GENERAL with the subcategories MOVABLE and IMMOVABLE PROPERTY in the regional medieval Scandinavian laws and makes a linguistic-geographical analysis of these words with the aim of establishing a relative term chronology. A crude analysis shows that fé/fæ for PROPERTY IN GENERAL and land for IMMOVABLE PROPERTY were the oldest
Enhancement of cAMP degradation by increased cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) activity is thought to be an important component of the mechanism whereby insulin counteracts catecholamine-induced lipolysis in adipocytes. In this study the selective cGI-PDE inhibitor OPC3911 was used to evaluate this role of cGI-PDE activation in intact rat adipocytes with special reference to changes
We have developed a new reactive force field, ReaxFF, for use in molecular dynamics (MD) simulations to investigate the structures and reactive dynamics of complex metal oxide catalysts. The parameters in ReaxFF are derived directly from QM and have been validated to provide reasonable accuracy for a wide variety of reactions. We report the use of ReaxFF to study the activation and conversion of p
Stationary and mobile field gamma spectrometry is a useful tool for rapid estimation of environmental radioactivity inventories on and in the ground. A weak point however, is that the depth distribution of the activity in the ground must be known in order to calculate the true activity per unit area or unit mass from an observed photon fluence rate. A promising method for converting incoming spect
