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In this study a Partial Least Squares Projection of Latent Structures (PLS) model has been developed forpredicting the rejection of pharmaceutical residuals by nanofiltration (NF) using treated municipalwastewater as feed. The objective was to provide a practical tool for wastewater reuse facilities for estimatingthe rejection of emerging organic contaminants based on their physiochemical characte
Reactions of 4-thio-2′-deoxyuridine d(s4U) and 4-thiouridine 5′-monophosphate s4UMP with trans-[AuY2Cl2]+/– (Y = CN– or NH3) have been investigated by conventional and high-pressure stopped-flow spectrophotometry in aqueous solution with 2.9 ⩽ pH ⩽ 7.0. For a given combination of metal complex and sulfur donor the observed second-order rate constants decreased with increasing pH. In the pH range 2
Background: Web-based interventions with a focus on behavior change have been used for pain management, but studies of Web-based interventions integrated in clinical practice are lacking. To emphasize the development of cognitive skills and behavior, and to increase activity and self-care in rehabilitation, the Web Behavior Change Program for Activity (Web-BCPA) was developed and added to multimod
The human placenta is a critical life-support system that nourishes and protects a rapidly growing fetus; a unique organ, species specific in structure and function. We consider the pressing challenge of providing additional advice on the safety of prescription medicines and environmental exposures in pregnancy and how ex vivo and in vitro human placental models might be advanced to reproducible h
In the late 19th century, political debates emerged in Sweden and Norway as well as in Finland concerning Travelling families – in this article defined as indigenous itinerant families whom the settled population pejoratively designated with terms such as ‘tatere’ (Norway), ‘tattare’ (Sweden) or ‘zigenare’ (Finland). In this article, these debates are compared, and the transfer of ideas and propos
We discuss finite volume effects and partial quenching for Chiral Perturbation Theory in the mesonic sector. The effects are computed in terms of analytical expressions for masses, decay constants and vacuum expectation values (VEVs) to two-loop order. Numerical examples are presented for a number of interesting and relevant cases. All numerical programs are publically available, the prospects of
SynopsisVarious protolytic species of thiols RSH (thioglycolic acid, l-cysteine, dl-penicillamine, and glutathione) in rapid equilibria with each other reduce trans-[Pt(CN)4Cl2]2- in parallel, halide-bridged electron transfer reactions. A linear Brønsted correlation between the reactivity of the thiolate anions RS- and their basicity is observed. The mechanism derived might be used as a model for
Marine energy technologies can contribute to meeting sustainability challenges, but they are still immature and dependent on public support. This paper employs the Technological Innovation Systems (TIS) framework to analyze the development and diffusion of Swedish marine energy up until 2014. While there were promising device developers, relevant industrial capabilities, and world-class research,
A chaos expanded Fourier split-step method is derived and applied to a narrow-angle parabolic equation. The parabolic equation has earlier been used to study deterministic settings. In this paper we develop a spectral-based Fourier split-step method that will take a limited degree of information about the environment into account. Our main focus is on proposing an efficient method for computationa
Enligt en etablerad teori om utvecklingen av politiskt styre i Europas förflutna går beskattning hand i hand med folkrepresentation. Härskare i finansiella trångmål blev nämligen mer eller mindre tvungna att erbjuda politiska fri- och rättigheter i utbyte mot folkets bidrag till statskassan. I denna avhandling undersöker jag det rakt motsatta antagandet: är det även så att icke-skatter går hand i According to a venerable argument about the formation of political regimes in historical Europe, taxation goes hand in hand with representation, as financial needs forced rulers to trade rights for revenue. In this dissertation I explore the reverse assumption, asking whether it is the case that non-taxation went hand in hand with non-representation? I argue that early modern rulers who had access
Atrial fibrillation (AF) is currently considered a risk factor for stroke. Depending on the severity of clinical factors (risk scores) a recommendation for full anticoagulation is made. Although AF is most certainly a risk factor for ischemic stroke, it is not necessarily the direct cause of it. The causality of association between AF and ischemic stroke is questioned by the reported lack of tempo
Artros är en vanligt förekommande ledsjukdom som kan leda till stelhet ochsmärta i den drabbade leden. Sjukdomen innebär att det sker en nedbrytning av det brosk som fungerar som smörjmedel och skyddande lager runt benändarna i leden. Nedbrytningen av brosket sker gradvis under flera år och oftast upptäcker man sjukdomen först i ett sent stadium när man börjar känna smärta eller få problem med rörOsteoarthritis (OA) is a degenerative disease that affects articular cartilage, which covers the surfaces of the bones in synovial joints. At later stages the disease can result in major loss of articular cartilage and thus lead to major disability. In order to allow for an early detection and treatment of OA, it is necessary to better understand the rather subtle biochemical changes in the cartil
The standard therapy for patients with haemophilia is prophylactic treatment with replacement factor VIII (FVIII) or factor IX (FIX). Patients who develop inhibitors against FVIII/FIX face an increased risk of bleeding, and the likelihood of early development of progressive arthropathy, alongside higher treatment-related costs. Bypassing agents can be used to prevent and control bleeding, as well
The aim of this systematic review was to examine the associations between diabetic retinopathy (DR) and the common micro- and macrovascular complications of diabetes mellitus, and how these could potentially affect clinical practice. A structured search of the PubMed database identified studies of patients with diabetes that assessed the presence or development of DR in conjunction with other vasc
The problem of designing a linear feedback when all state variables are not available is discussed. The design scheme is based on computation of a complete state feedback and a reduction to a specified structure. The reduction is made by approximation of the eigenspace corresponding to a set of dominant eigenvalues. The method consists of successive choices of weightings on this space. The method
Parasitoids foraging for larvae of Drosophila flies can use odours of adults of their hosts as well as odours of the food of their host larvae. Adult Drosophila deposit volatile aggregation pheromones into a substrate when mating and ovipositing. In this paper three species of parasitoids with different degrees of host specialization are compared in bioassays with regard to innate responses to agg
Objective: To survey potential predictors of success of mandibular advancement device (MAD) therapy in patients with obstructive sleep apnea (OSA), and in particular, to examine anatomical narrowings and sleep-related collapse levels in the upper airway. Methods: This was a prospective study of 62 OSA patients (median apnea–hypopnea index [AHI] of 34), who were treated with a custom-made, monobloc
In this paper we derive the finite-sample distribution of the estimated weights of the tangency portfolio when both the population and the sample covariance matrices are singular. These results are used in the derivation of a statistical test on the weights of the tangency portfolio where the distribution of the test statistic is obtained under both the null and alternative hypotheses. Moreover, w
