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Different studies on the stability of high density lipoprotein cholesterol (HDL) in frozen serum or plasma have yielded conflicting results, namely increase, decrease, or no change at all during prolonged storage under freezing conditions. As part of a major trial on lipid-lowering strategies we statistically demonstrated a time-related decrease in HDL cholesterol during storage up to 46 months at

Disease gene identification is still a challenge despite modern high-throughput methods. Many diseases are very rare or lethal and thus cannot be investigated with traditional methods. Several in silico methods have been developed but they have some limitations. We introduce a new method that combines information about protein-interaction network properties and Gene Ontology terms. Genes with high

Sclerosing injections under ultrasonographic guidance is a new method of treatment for persistent pain in Achilles tendinosis. Good results, even superior to those of surgery, have been described. We report the outcome of 25 patients with midportion tendinosis receiving sclerosing treatment. Twenty-eight consecutive patients (29 tendons) with ultrasonographical findings of midportion tendinosis ex

Human papillomavirus (HPV) infection causes cervical cancer and genital warts. Young women (1106) were randomized to receive one of three formulations of a quadrivalent HPV (Types 6/11/16/18) L1 virus-like particle (VLP) vaccine or one of two placebo formulations. The goal was to assess vaccine safety and immunogenicity in baseline HPV 6/11/16 or 18-naive and previously infected subjects. All thre

BACKGROUND: In a previous study, we reported an increased prevalence of thyroperoxidase antibodies (TPOA) in patients with bipolar disorder. Here we report the prevalence of other organ-specific autoantibodies: H/K adenosine triphosphatase (ATPA), glutamic acid decarboxylase-65 (GAD65A), and GAD-67 (GAD67A). METHODS: ATPA, GAD65A, and GAD67A were determined (via a commercially available enzyme lin

A systematic study was conducted over six years (1994-1999) on a shallow ice covered lake in the Russian Republic of Karelia with the aim of developing better understanding of some physical processes occurring in shallow ice-covered lakes. The average ice-covered period was 182 days while the longest ice-covered period was 193 days. The average lake water temperature at ice formation was 0.5-10deg

This article explores whether the impact of marital status on the risk of preterm birth varies in relation to marital practices in the population, defined by the proportion of out-of-marriage births. Data come from a case–control study of the determinants of preterm birth in 16 European countries (5456 cases and 8234 controls). There is a significantly elevated risk of preterm birth associated wit

Pregnancy is rare in Parkinson's disease (PD). In the literature on studies of antiparkinsonian drugs in animals during pregnancy, there are reports on malformations of the skeletal and circulatory system. However, the majority of studies in animals have not shown any teratogenicity. Amantadine has been teratogenic in rats and selegiline has caused neurochemical and behavioral alterations in rats

The Mediterranean Sea has been identified as one of the hotspots for climate change. Intense warming in the Mediterranean Sea may have strong implications for biological activity and ecosystem functioning. To elucidate the effects of warming on planktonic and benthic metabolism, we performed experiments under different increasing temperature regimes, ranging from three to six different temperature

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Tramways are a sustainable and accessible mode for public transport. They promote urban development and contribute to a more attractive city. Light rail, but also public transport as a whole, is an important part of society as it is accessible to everyone and reduces the amount of cars needed. The two tramlines in Norrköping account for two thirds of public transport travel in the city. The purpos

Minoritetsstress på grund av etnisk bakgrund är ett nytt område inom forskningsfältet minoritetsstress. Det saknas ett mätinstrument för denna typ av stress. Denna studie syftade till att utifrån Meyers (2003) koncept minoritetsstress, konstruera ett mätinstrument för mätning av etnisk minoritetstress (EMS); samt se minoritetsstressens relation till allmän stress, anknytning och coping för att undMinority stress due to ethnic background is a new area in the research field. Based on Meyer's (2003) concept of minority stress, this study aimed to construct an instrument for measuring ethnic minority stress (EMS); and study minority stress and its relation to general stress, attachment and coping to investigate whether attachment and coping can become dimensions that can be used to disting

I dagens medicinsktekniska förlossningskultur är det viktigt att det finns tillgång till alternativ smärtlindring såsom bad. För att kartlägga vilka möjligheter kvinnor har att använda sig av bad som förlossningssmärtlindring skickades en enkät till avdelningsföreståndarna på samtliga förlossningskliniker i Sverige. Svarsfrekvensen var 100 %. Tillgång på bad som förlossningssmärtlindring ansåg 88

Denna uppsats behandlar EU:s nya regler som förändrar kravet på prospekt - ett detaljerat informationsdokument som företag måste publicera när de erbju-der aktier till allmänheten eller noterar dem på en marknadsplats. Prospektet skyddar investerare genom att ge klar information om företaget, aktierna och riskerna, så att de kan fatta välgrundade beslut. Uppsatsen fokuserar på "tröskelvärdet&This essay discusses how the EU's new regulations change the requirement for prospectus - a detailed information document that companies must publish when offering shares to the public or listing them on a marketplace. The prospectus protects investors by providing clear information about the company, the shares, and the risks, enabling them to make well-informed investments. The essay focuses

While studies on the relationship between health, income, healthcare spending and productivity is generally consistent, little attention has been brought to the regional contexts. Meanwhile, a country like Sweden who is generally known for a well-established healthcare system and welfare state, experiences increasing regional disparities. This thesis investigates the relationship between health, i