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Introduction: A subgroup of severe Traumatic Brain Injury (TBI) patients, known as ultra-severe (us-TBI), is most commonly defined as a post-resuscitation Glasgow Coma Scale (GCS) of 3–5. There is uncertainty on whether these critically injured patients can benefit from neurosurgical intervention. Research question: The available evidence regarding the decision-making and outcome following managem

Med denna guide vill vi ge forskningsbaserade råd om hur du kan minska dinklimatpåverkan genom att förändra dina levnadsvanor, och leva i linje medParisavtalets 1,5-gradersmål. Vi vill både visa svenskars genomsnittliga klimat-avtryck och den stora skillnaden mellan individers koldioxidavtryck. Det innebär attdet behövs olika vägval för de som vill förändra sina levnadsvanor. Guiden betonardessutoSyftet med denna guide är att ge forskningsbaserade råd om de mest effektiva sätten att minska sitt koldioxidavtryck för en genomsnittlig person i Sverige. Samtidigt visar den att individuella livsstilsförändringar måste kombineras med och stödjas av förändringar i det omgivande samhället. Dessutom ger guiden en allmän fingervisning om storleken på ditt koldioxidavtryck och om vilka delar av din v

Acute myeloid leukemia (AML) is characterized by a differentiation block leading to accumulation of immature cells. Chromosomal translocations in AML affect transcription factors that are involved in regulation of myeloid differentiation. Aberrant expression of these factors interferes with differentiation events and has a role in the pathogenesis of AML through superactivation or (dominant negati

Introduction: Gender affirming surgery of primary and/or secondary sex characteristics has been shown to alleviate gender dysphoria. A descriptive snapshot of current treatment preferences is useful to understand the needs of the transgender population seeking health care. This study aimed to describe preferences for gender affirming treatment, and their correlates, among individuals seeking healt

Slope stability is an important aspect in the management of civil engineering projects. The stability of earth slopes is a significant concern for safety and the economy. There are several methods for finding the safety factor. Spencer's method is considered one of the most accurate methods for calculating the factor of safety but it depends on the others on dividing the slope geometry into the nu

The performance of heritage takes place in prestigious institutions such as museums and archives, in officially sanctioned spaces such as jubilees and public monuments, but also in more mundane, ephemeral and banal cultural practices, such as the naming of phenomena, viewing exhibitions or walking in the countryside. This volume examines the performance of Nordic heritage and the shaping of the ve

After decades of development of information systems dedicated to health professionals, there is an increasing demand for personalized and non-hospital based care. An especially critical domain is cardiology: almost two third of cardiac deaths occur out of hospital, and victims do not survive long enough to benefit from in-hospital treatments. We need to reduce the time before treatment. But sympto