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Time-lapse imaging of Streptomyces hyphae revealed foci of the essential protein DivIVA at sites where lateral branches will emerge. Overexpression experiments showed that DivIVA foci can trigger establishment of new zones of cell wall assembly, suggesting a key role of DivIVA in directing peptidoglycan synthesis and cell shape in Streptomyces.

BACKGROUND: Current studies reveal a lack of consensus for the evaluation of physical and psychosocial problems after ICU stay and their changes over time. OBJECTIVES: The aim was to develop and evaluate the validity and reliability of a questionnaire for assessing physical and psychosocial problems over time for patients following ICU recovery. PATIENTS: Thirty-nine patients completed the questio

Background: Previous studies have indicated that transthyretin (TTR) levels in cerebrospinal fluid (CSF) are altered in depression and dementia. The present study aimed to investigate whether CSF TTR can be used to discriminate between patients with Alzheimer's disease (AD) and patients with dementia with Lewy bodies (DLB) with or without medication, as well as to reveal whether CSF TTR correlates

In this paper we demonstrate the presence of two novel in vivo autophosphorylation sites in the c-Kit/stem cell factor receptor (c-Kit/SCFR): Tyr-703 in the kinase insert and Tyr-936 in the C-terminal tail. We furthermore demonstrate that the adapter protein Grb2 is a specific binding partner for both phosphorylated Tyr-703 and phosphorylated Tyr-936, whereas the adapter protein Grb7 binds selecti

Objective: An intervention to structure patient-key worker communication has been tested in a randomized controlled trial. The aim of this paper was to investigate effectiveness of the intervention in terms of moderators of effectiveness. Method: A total of 507 patients with schizophrenia were included. Moderators of effectiveness were investigated using two-way anovas. Results: Patients with a be

OBJECTIVE To determine whether hydrogen peroxide vapor (HPV) could be used to decontaminate caliciviruses from surfaces in a patient room. DESIGN Feline calicivirus (FCV) and murine norovirus (MNV) were used as surrogate viability markers to mimic the noncultivable human norovirus. Cell culture supernatants of FCV and MNV were dried in triplicate 35-mm wells of 6-well plastic plates. These plates

Radiative lifetimes for six highly excited levels in Fe II have been measured at Lund Laser Centre applying the laser induced fluorescence technique and two-step excitation. The energy levels belong to the even-parity 3d(6)(D-5)(4)d subconfiguration at about 10 eV. Branching fractions (BF:s) of 29 transitions from these levels to the 3d(6)(D-5)4p subconfiguration at about 5 eV have been measured i

No study has investigated the predictive validity and cut-off scores in diagnostic tests for falls used in in-home assessment in frail older people. The objective was to investigate the predictive validity for falls in the Downton Fall Risk Index (DFRI), Timed Up and Go (TUG) and Romberg test (RT) used in in-home assessment of frail older people (65+ years). Data on the diagnostic tests were colle

A number of different intervention programmes have been described in the literature for caregivers of people with dementia, but the nature of intervention has varied widely. The aim of the present study was to evaluate the efficacy of psychosocial intervention on family caregiver's level of burden and satisfaction, and possible influence of the caregiver's relationship and health and the patient's

OBJECTIVES: /st> Because standard immunosuppressive treatment for antineutrophil cytoplasm antibody-associated vasculitis (AAV) (granulomatosis with polyangiitis (Wegener's) (GPA) and microscopic polyangiitis (MPA)) has been associated with a significant risk of developing cancer, the cancer incidence of treated AAV patients was assessed. METHODS: /st> This analysis concerned 535 patients with new

Abstract When studying the deposition of particles in wind tunnel experiments, we measure theairborne particles with an Aerodynamic Particle Sizer (APS). The deposited particles are examined with an optical microscope connected to an image analyzer. Calibration between the APS and the optical microscope determinations of particle size has been performed for particles of fused alumina. The particle

OBJECTIVES: Acute superior mesenteric artery (SMA) occlusion can be diagnosed in an early phase by computed tomography (CT) angiography, which is also a prerequisite for endovascular intervention. However, the issue of development of postoperative permanent renal failure due to contrast-induced nephropathy has not been evaluated. DESIGN: Retrospective MATERIALS: A total of 55 patients with acute S

Aim: This study aimed to develop a universally applicable core set of quality indicators for Hirschsprung's disease care through a consensus-driven process, to standardise and improve care quality across Europe. Methods: A modified Delphi method was used to achieve consensus among healthcare professionals (HPs) and patient representatives (PRs) across Europe. Participants completed three rounds of

Urban planning is increasingly embedded in a neoliberal paradigm, resulting in decentralization and deregulation of planning practice. This affects how compact cities are materialized. However, few studies of the effects of neoliberal planning for density consider the resulting geographies of green space. To address this research gap, this paper explores how the idea of green space is being reconf

Objective: Progressive Supranuclear Palsy (PSP) is a severe neurodegenerative disease characterized by tangles of hyperphosphorylated tau protein and tufted astrocytes. Developing treatments for PSP is challenging due to the lack of disease models reproducing its key pathological features. This study aimed to model sporadic PSP-Richardson's syndrome (PSP-RS) using multi-donor midbrain organoids (M

Purpose: Mental illness due to longstanding stress is increasing. It has been shown that service users with mental illness may benefit from nature-based interventions (NBI), including equine-assisted therapy, to support their health, recovery, and activity level of daily life. However, the evidence base to support this is still weak. The aim was thus to evaluate and provide knowledge of the possib

The moult of Barred Warblers Sylvia nisoria was studied during three winter seasons in southeastern Kenya at a southward passage site (Ngulia) and a wintering site (Mtito Andei). Most Barred Warblers migrating through Ngulia in November had yet to commence winter moult. These birds probably moulted subsequently in winter in northern Tanzania. In December, birds were found in heavy moult at Mtito A

BACKGROUND: One of the critical challenges with capitation payment to primary care providers is ensuring that the fixed payments are equitable and adjusted for expected care needs. Patients of lower socioeconomic status (SES) generally have higher health care need. Sweden developed a Care Needs Index, which is used in the capitation payments to primary care providers to account for patient SES.OBJ

This article presents a critical appraisal of the European Union’s (EU) policy process that delivered the Critical Raw Materials Act, 2023–⁠2024. We combine Marxist-Gramscian perspectives on regional blocs and social movement theory on transnational contestation to study a framing contest at two points in the policy process. First, we examined environmental justice frames in technical campaigns to