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Individual genome-wide scans of blood pressure (BP) and hypertension (HT) have shown inconsistent results. The aim of this study was to investigate whether there was any consistent evidence of linkage across multiple studies with similar ethnicity. We applied the genome-search meta-analysis method (GSMA) to nine published genome-wide scans of BP (n=5) and HT (n=4) from Caucasian populations. For e
OBJECTIVE: Previous studies have shown possible neuroendocrine effects of GH. In the present study we investigated the incidence of mental disorders and the prevalence of mental distress and cognitive dysfunction in hypopituitary women with untreated GH deficiency compared to population-based controls.DESIGN AND PATIENTS: Thirty-three hypopituitary women with a median age of 64 years (range 39--77
For local administration of drugs or enzyme inhibitors in the human gut, a small-bore, smooth tube was introduced through the nose, retrieved from the pharynx, equipped with a firm radio-opaque capsule, and swallowed. Peristalsis moves the capsule to the desired location in the gut where it is anchored before administration via the tube. Drug uptake is followed by plasma sampling. One capsule typ
BACKGROUND: The risk for type 1 diabetes mellitus (T1DM) and celiac disease (CD) is related to human leukocyte antigen (HLA) DQA1, DQB1 and DRB1 loci. Unfortunately, HLA typing has been too difficult and costly for frequent use. Automated genotyping focused on risk alleles could provide access to HLA typing in diagnostic evaluations, epidemiological screening and contribute to preventive strategie
The capability of the antibody (Ab) repertoire to mount a response to appropriate epitopes on infectious agents will strongly affect the ability of the immune system to provide protection against disease. Certain epitopes may be poor inducers of immunity but are nevertheless able to promote biologically important protection when recognized by the immune repertoire. We have investigated the recogni
Growth anomaly of trees in some regions was detected under current episode of rapid warming. Thisraises a dilemma for temperature reconstructions by using tree-ring width which is believed to be themost important proxy on inter-annual temperature reconstruction during the past millenniums. Here weemployed the tree-ring d13C to reconstruct temperature variations for exploring their potential oncapt
The integration of daylight and electric lighting, considering user satisfaction and energy savings potentially can contribute significantly to reduce energy demand for lighting, that represents 18% of global energy demands. This paper presents the work and first results of IEA SHC Task 61/EBC Annex 77 “Integrated Solutions for Daylighting and Electric Lighting: From component to user centered
The effectiveness of public health measures to prevent COVID-19 contagion has required less vulnerable citizens to pay an individual cost in terms of personal liberty infringement to protect more vulnerable groups. However, the close relationship between scientific experts and politicians in providing information on COVID-19 measures makes it difficult to understand which communication source was
Background: Concurrent chemoradiotherapy is standard treatment for limited stage small-cell lung cancer (SCLC). Twice-daily thoracic radiotherapy of 45 Gy in 30 fractions is considered to be the most effective schedule. The aim of this study was to investigate whether high-dose, twice-daily thoracic radiotherapy of 60 Gy in 40 fractions improves survival. Methods: This open-label, randomised, phas
Background: Early detection of renal cell carcinoma (RCC) has the potential to improve disease outcomes. No screening program for sporadic RCC is in place. Given relatively low incidence, screening would need to focus on people at high risk of clinically meaningful disease so as to limit overdiagnosis and screen-detected false positives. Methods: Among 192,172 participants from the European Prospe
Uppsatsen analyserar behovet av intern förändringskommunikation mellan ledning och medarbetare vid bildandet av kommunalförbundet Räddningstjänsten Syd. Vidare studeras också uppkomsten av brister i den interna kommunikationen och hur detta kan ligga till grund för medarbetarnas negativa attityd till förändringsarbetet. Studiens empiriska material är insamlat genom intervjuer med ledning, medarbet
Som en följd av att informationskompetens lyfts fram i Bolognaprocessen som ett betydelsefullt element i all högre utbildning har ämnet uppmärksammats i stigande grad inom universitetsvärlden. Bolognaprocessen har även föranlett ändringar i svensk lagstiftning som gör kursplaner till juridiskt bindande dokument. Kursplanernas lärandemål måste examineras för att man ska kunna säkerställa att de har
Utgångspunkten för följande uppsats är dynamiken mellan Föräldrabalken, FB, 6:8 och artikel 8 Den europeiska konventionen angående skydd för de mänskliga rättigheterna och de grundläggande friheterna, EKMR. FB 6:8 innebär ett ingrepp i familjen då vårdnaden om ett barn flyttas över på någon utanför familjen. Detta ingrepp i familjen som FB 6:8 medför innebär inte enkom att den faktiska vårdnaden ö
Uppsatsen syftar till att undersöka sambandet mellan religion och politik utifrån ett antagande om att globaliseringsprocessen spelat en viktig roll för ökad religiositet i den politiska sfären. Utifrån en idé- och ideologianalys med kritiska inslag fokuserar vi främst på statsmaktens förändrade roll, i och med globaliseringsprocessen. Vi använder oss av en socialkonstruktivistisk teori då vi tror
This paper addresses the problem of urban transport management in Sofia ? the capital city of Bulgaria. It highlights the tensions and contradictions in the current policy and practice and suggests that the adoption of mobility management in policy making would elevate municipal capacity to deal with complex transport-environment conflicts and set the framework for a sustainable development of the
