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Discrete gene loci regulate neurodegeneration, lymphocyte infiltration, and major histocompatibility complex class II expression in the CNS

Neurodegeneration and inflammation are fundamental aspects of many neurological diseases. A genome-wide scan of the response to ventral root avulsion (VRA) in a rat F2 cross discloses specific gene regions that regulate these processes. Two gene loci displayed linkage to neurodegeneration and T cell infiltration, respectively, and a single locus displayed extreme linkage to VRA-induced major histo

A population of atypical CD56(-)CD16(+) natural killer cells is expanded in PTSD and is associated with symptom severity

INTRODUCTION: Post-traumatic stress disorder (PTSD) has been associated with immune disturbances, including a higher incidence of infections and autoimmune diseases as well as a net pro-inflammatory state. Natural killer (NK) cells, a key component of the innate immune system, have been less well-studied in PTSD despite their importance in immunity.METHODS: We studied two independent samples of co

Tissue temperature monitoring during interstitial photodynamic therapy

During δ-aminolevulinic acid (ALA) based Interstitial Photodynamic Therapy (IPDT) a high light fluence rate is present close to the source fibers. This might induce an unintentional tissue temperature increase of importance for the treatment outcome. In a previous study, we have observed, that the absorption in the tissue increases during the treatment. A system to measure the local tissue tempera

Funktionshindrad - med rätt till arbete? En komparativ studie av arbetsrättsliga regleringar kring arbete och funktionshinder i Sverige, England och Tyskland.

Popular Abstract in Swedish Arbete är centralt i det moderna samhället. Samtidigt står många människor av olika anledningar utanför den ordinarie arbetsmarknaden. Att detta i särskild utsträckning gäller personer med funktionshinder har i många länder fått till följd att lagstiftning antagits för att på olika sätt öka arbetskraftsdeltagandet för denna grupp. De bestämmelser som reglerar arbete ochThis doctoral thesis examines labour market legislation on disability and work in Sweden, England and Germany. In order to provide increased access to the labour market for people with disabilities all three studies countries have undertaken more of less far-reaching legislative measures over a number of decades, both in line with, or as a result of, general labour and employment legislation, but

From Medication to Education - People with autism in adult psychiatry

This dissertation concerns the field of applied psychiatry and focuses on the problems that are associated with the care and treatment of adult patients with autism spectrum disorders. The conditions that are described are valid for Swedish psychiatry and cannot be directly generalized to conditions outside of the country.

Living and Dying with Primary Sjögren's Syndrome Studies on Aetiology, Treatment, Lymphoma, Survival and Predictors

Popular Abstract in Swedish Denna avhandling hade som målsättning att belysa långtidsförloppet vid primärt Sjögrens syndrom (SS). Studierna är baserade på registret över SS-patienter vid Universitetssjukhuset MAS och de Amerikansk-Europeiska konsensuskriterierna för SS från 2002. Helicobacter pylori (H. pylori) är inte mer prevalent bland SS-patienter än bland kontrollpersoner. Bakteriens förekomThis work was aimed at improving our understanding of the course of primary Sjögren's syndrome (SS). The Malmö SS patient register and the 2002 American-European Consensus Criteria formed the basis of all studies. Helicobacter pylori (H. pylori) was not more prevalent in SS patients or associated with severe glandular or immunological dysfunction. Consequently, our results do not support screenin

A new concept for large deformable mirrors for extremely large telescopes

For extremely large telescopes, there is strong need for thin deformable mirrors in the 3-4 m class. So far, feasibility of such mirrors has not been demonstrated. Extrapolation from existing techniques suggests that the mirrors could be highly expensive. We give a progress report on a study of an approach for construction of large deformable mirrors with a moderate cost. We have developed low-cos

Ett nytt fackligt landskap - i Sverige och utomlands

Ur ett hundraårsperspektiv har arbetsmarknaden genomgått avsevärda förändringar. Majoriteten av löntagarna utgörs numera av tjänstemän. I Sverige svarar de även för majoriteten av fackmedlemmarna. De svenska fackföreningarna tillämpade redan tidigt en bred medlemsrekrytering, men till bilden hör också att Sverige har världens mest klassuppdelade fackliga rörelse. Inte minst för tjänstemännen har d

How do scientists develop and use scientific software?

New knowledge in science and engineering relies increasingly on results produced by scientific software. Therefore, knowing how scientists develop and use software in their research is critical to assessing the necessity for improving current development practices and to making decisions about the future allocation of resources. To that end, this paper presents the results of a survey conducted on

A method for supporting the integration of packaging development into product development

This paper aims to support the decision-making tasks regarding the integration of packaging development into product development. Based on the study of the interactions of the product and packaging during the whole product life cycle, a set of packaging-related factors was extracted and mapped to a general product development model, which at a strategic level can be used to define an integrated pr

Kränkning och upprättelse : En rättssociologisk studie av kränkningsersättning till brottsoffer

Popular Abstract in SwedishKränkningsersättning förutsätter enligt lagtexten en ”skada” men det är inte en fysisk eller medicinskt påvisbar personskada som avses, snarare är det den personliga integritetskränkning som brottsliga angrepp kan medföra. Ersättningen är tänkt att ge kompensation för den kränkning som brottet medfört så att brottsoffret får upprättelse. Men är det möjligt att ersätta enThe thesis takes its starting point in the question of how damages for violation of crime is determined. This type of non-pecuniary damages to crime victims has a fundamental uncertainty regarding the computation of damages and what is really meant by “violation” in the meaning of the law. There is also a gliding between the violation and the suffering, as to which the compensation is related. The

How to age right and care(fully) at home? : A protocol for a multistage comparative study of ageing in place and hospital at home care across three countries

INTRODUCTION: Ageing right care(fully) is a transnational research study which explores and maps an understanding of the care pathways between ageing in place and hospital at home policy and practices for older adults in Israel, the Netherlands and Sweden. The countries are suited to be compared where they have growing, ageing populations, a focus on healthcare reform and several policies to reduc

Diamonds for X-ray optical applications at 3rd and 4 th generation X-ray sources

There is currently interest in low strain HPHT diamond due to its expected application as various types of X-ray optical elements at Synchrotrons, where the X-ray intensity is becoming progressively too severe for the existing materials. The diamond crystals need to be synthesised with unprecedented lattice quality. In recent measurements at the ID19 beamline of European Synchrotron Radiation Faci

Life cycles final abstrakt bok 190426

Microsoft Word - Abstrakt bok G5 1 Life Cycles: Human Reproduction, Growth, and Development Thursday May 9th to Friday May 10th 2019 At “Jubileumsaulan” Lecture Hall, Jan Waldenströms gata 2-5, Skåne University Hospital (SUS), Malmö, Sweden Organised by: The Strategic Research Area (SRA) Epidemiology for Health (EpiHealth) at Lund and Uppsala Universities in collaboration with ReproUnion 2.0, the

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/life_cycles_final_abstrakt_bok_190426.pdf - 2026-05-29

Miljohandbok

Generella rutiner / regler för laborativ verksamhet inom BMC MILJÖHANDBOK för GEOCENTRUM I LUND Generella råd / rutiner / regler och information för verksamheten inom Geologiska institutionen , GeoCentrum Augusti 2006 www.geol.lu.se/ http://www.geol.lu.se/ INNEHÅLL I Inledning II Byggnad och lokaler III Speciella lokaler IV Elsystem och belysning V Tele/data VI Larm VII Inneklimat och ventilation

https://www.geologi.lu.se/sites/geologi.lu.se/files/miljohandbok.pdf - 2026-05-29