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Background Transcatheter aortic valve replacement (TAVR) has become an established therapeutic option for patients with symptomatic, severe aortic valve stenosis (AS) who are ineligible or at high risk for conventional valvular surgery. In Northwestern Europe, the TAVR technology is also increasingly used to treat patients with an intermediate risk profile. Methods and results The study was design
Developmental dysplasia of the hip (DDH) is associated with an increased risk of early hip osteoarthritis (OA). We aimed to examine the outcome at the completion of growth in a cohort of children who had residual acetabular dysplasia at age 1 year following early treatment for neonatal instability of the hip (NIH).
Histopathology Analysis of sentinel node biopsy - a single-institution experience supporting the use of serial sectioning and immunohistochemistry for detection of micrometastases by comparing four different histopathological laboratory protocols Aims: Detecting micrometastases (>0.2 and ≤2 mm/>200 cells) and isolated tumour cells (ITCs; ≤0.2 mm/<200 cells) is important for staging of breast canc
Stress-related disorders are a frequent cause for sick leave, with consequences such as great distress and adverse economic effects for the affected person and substantial costs for society. Identifying effective interventions that facilitate return to work is thus important. The aim of this study was to evaluate the effectiveness of the 16-week Redesigning Daily Occupations program as a work reha
PURPOSE: The aim of the present study was to examine changes in the expression of intracellular signal-transduction pathways, specifically mitogen-activated protein kinases, following retinal ischemia-reperfusion. METHODS: Retinal ischemia was induced by elevating the intraocular pressure in porcine eyes, followed by 5, 12, or 20 h of reperfusion. The results were compared to those of the sham- op
Lake Poopó is a terminal lake of the Bolivian Altiplano, with high salinity and heavy anthropogenic pollution from centuries of extensive mining activity. This study aims to describe how the water quality of groundwater and surface water system in different subwater-sheds of the Lake Poopó varies with geology and hydrology. Measurements of total dissolved solids (TDS) in wells show groundwater bec
Hepatitis B virus (HBV), hepatitis delta virus (HDV), and hepatitis C virus (HCV) remain leading drivers of chronic viral hepatitis, cirrhosis, hepatocellular carcinoma, and liver-related mortality. This ESCMID Study Group for Viral Hepatitis (ESGVH) narrative review summarizes recent advances and expert perspectives in the field. For HBV, emerging biomarkers such as quantitative HBs antigen, HBV
Hepatitis A virus (HAV) remains a preventable cause of acute viral hepatitis, with an estimated 159 million new infections and 39 000 deaths in 2019. Although improved care and hygiene reduced deaths, global incidence rose by approximately 4%, driven by increased symptomatic cases and population growth. The availability of safe and highly immunogenic vaccines and the absence of chronic carriage ma
Influenza A virus (IAV) is a major respiratory pathogen, causing around 650,000 deaths annually. Asignificant transmission pathway for IAV is via expelled respiratory aerosol. For successfultransmission via the aerosol route, IAV must remain infectious following transport from an infectedhost to a susceptible individual. Many environmental factors may affect IAV infectivity, includingambient relat
A search is presented for new particles produced in proton-proton collisions at a centre-of-mass energy of 13 TeV that result in final states comprising a massive vector (W or Z) boson that decays hadronically and large missing transverse momentum. The data sample was collected with the ATLAS experiment at the Large Hadron Collider from 2015 to 2018 and corresponds to an integrated luminosity of 1
A search for heavy pseudo-scalar (A) and scalar (H) Higgs bosons decaying into a top-quark pair (tt¯) has been performed with 140 fb−1 of proton-proton collision data collected by the ATLAS experiment at the Large Hadron Collider at a centre-of-mass energy of s = 13 TeV. Interference effects between the signal process and Standard Model (SM) tt¯ production are taken into account. Final states with
A search for a new heavy boson produced via gluon-fusion in the four-lepton channel with missing transverse momentum or jets is performed. The search uses proton-proton collision data equivalent to an integrated luminosity of 139 fb−1 at a centre-of-mass energy of 13 TeV collected by the ATLAS detector between 2015 and 2018 at the Large Hadron Collider. This study explores the decays of heavy boso
In addition to the family context, persons in the neighborhood and community are important for individual life course, socioeconomic and demographic outcomes such as education, career and family transitions. This paper aims to study how neighborhood conditions in childhood influence fertility outcomes in adulthood. Theories focusing on motivation, aspirations and attitudes or peer influence genera
Metal joining remains an essential yet challenging process in manufacturing, particularly for components with small dimensions, multiplex, delicate geometries, or dissimilar metals, where conventional joining methods can be insufficient. Here, we introduce Gas Actuated Bonding (GAB), a novel joining method that employs gaseous melting-point-depressant (MPD) agents to induce a diffusion-active stat
Purpose. Continuous minor steps of improvement in the management of breast cancer have resulted in decreased mortality rates during the last decades. The aim of this study was to compare the clinical outcome of patients with stage I breast cancer diagnosed during two time periods that differed with respect to adjuvant systemic therapy. Material and methods. The studied population consisted of all
While sharing good teaching practice is at the core of most academic developers’ professional roles, little systematic evidence has been collected on this topic so far. This paper investigates if, how and for what specific purposes academic developers collect and share teaching artefacts. We report on an exploratory, survey-based study among academic developers from around the world. Our findings
This paper analyses what effect an application of a specific poststructural feminist theory has on the Swedish classification system SAB. The purpose is to study if it is possible to open up the current representation of gender towards a more multiple one. The study is both theoretical and empirical. The theoretical part include a short presentation of both classification theory and feminist theor
