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BACKGROUND: Diesel engine exhaust causes adverse health effects. Meanwhile, the impact of renewable diesel exhaust, such as hydrotreated vegetable oil (HVO), on human health is less known. Nineteen healthy volunteers were exposed to HVO exhaust for 3 h in a chamber with a double-blind, randomized setup. Exposure scenarios comprised of HVO exhaust from two modern non-road vehicles with 1) no aftert
X-ray fluorescence microscopy performed at nanofocusing synchrotron beamlines produces quantitative elemental distribution maps at unprecedented resolution (down to a few tens of nanometres), at the expense of relatively long measuring times and high absorbed doses. In this work, a method was implemented in which fast low-dose in-line holography was used to produce quantitative electron density ma
Energy is among the main driving forces needed for sustainable development. Provision of energy services, from the supply side to transmission/distribution and use, must include management, and good management requires tools. Energy planning is a tool for managing the community energy system through assessing and balancing supply and demand. This thesis explains an approach to energy planning whic
The deposited dose of particles in the respiratory tract is an important factor for understanding health effects of aerosol particles. It is a combination of the exposure, volume of inhaled air and particle deposition. At increasing activity the minute ventilation ( volume of breath x number of breaths ) increase . Little is known about if and how this affects the regional particle deposition.
I min avhandling undersöker jag varierande placering av objekt till verb i svenskans historia. Primärt undersöks placering av nominala objekt visavi negerande adverbial, och sekundärt undersöks placering av nominala objekt visavi andra argument (subjekt och objekt) i huvudsatser. Materialet som ligger till grund för avhandlingen är texter från äldre och yngre fornsvenska (1225-1526), och huvudsaklThis thesis focuses on the distribution of objects in the history of Swedish. The primary focus of the thesis is the distribution of objects relative to negation, and the secondary focus is varying order of nominal arguments in Old Swedish (1225–1526).In Modern Swedish, objects may precede the negation, often referred to as Object Shift, OS, or precede a subject, often referred to as Long Object S
There is a long history of avian studies investigating the impacts of urbanization. While differences in several life-history traits have been documented, either between urban and rural populations or across generalized urbanization gradients, a detailed understanding of which specific environmental variables cause these phenotypic differences is still lacking. Here, we quantified several local en
The respiratory epithelium consists of multiple, functionally distinct cell types and is maintained by regionally specific progenitor populations that repair the epithelium following injury. Several in vitro methods exist for studying lung epithelial repair using primary murine lung cells, but isolation methods are hampered by a lack of surface markers distinguishing epithelial progenitors along t
Achieving CRISPR Cas9-based manipulation of mitochondrial DNA (mtDNA) has been a long-standing goal and would be of great relevance for disease modeling and for clinical applications. In this project, we aimed to deliver Cas9 into the mitochondria of human cells and analyzed Cas9-induced mtDNA cleavage and measured the resulting mtDNA depletion with multiplexed qPCR. In initial experiments, we fou
In this article some initial results from the projects "Bronsildems deglar" (en. "Bronze Age melting crucibles") and "Deglarna frin Bokenäs" (en. "The crucibles from Bokenäs") are presented. The aim of the projects is to expand our knowledge of the production, use and discard of technical ceramics in south Sweden using laboratory analysis. This article describes the results and conclusions made bIn this article some initial results from the projects "Bronsildems deglar" (en. "Bronze Age melting crucibles") and "Deglarna frin Bokenäs" (en. "The crucibles from Bokenäs") are presented. The aim of the projects is to expand our knowledge of the production, use and discard of technical ceramics in south Sweden using laboratory analysis. This article describes the results and conclusions made b
Research question: How are organizations integrating ethical and strategic considerations into their approaches to AI implementation? Purpose: The purpose of this research is to systematically map ethical and strategic themes relevant to Artificial Intelligence Systems within the business context from a practitioner standpoint. This study aims to contribute to the understanding of this research fi
Under de senaste åren har terrorattentat i Kenya uppmärksammats och diskuterats. Efter 9/11 har Kenya blivit det land i Afrika som har klassats som en frontlinje för att bekämpa terrorismen tillsammans med USA. I samband med Kenyas terrorismbekämpning har handlingar mot somaliska flyktingar ifrågasatts och Human Rights Watch är en av de organisationer som har rapporterat om händelser under en långIn recent years, terror attacks in Kenya have been observed and discussed. After 9/11 Kenya has become the frontline of Africa, fighting terrorism alongside the United States. As a result of the fight against terrorism, questions regarding the treatment of Somalian refugees arise. Human Rights Watch is one of many organizations to rapport on such events for a period of time. With this in mind, the
Aim and objectives: To explore newly employed nurses’ socialisation in the process of introduction into an oncological clinic from the perspectives of unit managers and newly employed nurses. Background: There are managerial challenges in retaining nurses at workplaces. The way in which nurses are socialised into their work is important for their job satisfaction and retainment. Method: Qualitativ
Diamond Blackfan Anemia (DBA) is a congenital bone marrow failure syndrome associated with ribosomal gene mutations that lead to ribosomal insufficiency. DBA is characterized by anemia, congenital anomalies, and cancer predisposition. Treatment for DBA is associated with significant morbidity. Here, we report the identification of Nemo-like kinase (NLK) as a potential target for DBA therapy. To id
CVD and cancer are the two leading causes of death worldwide. Improvement in cancer early detection and treatment has resulted in an increased number of cancer survivors. However, many of the survivors tend to develop CVD often leading to their demise. Conversely, people with pre-existing CVD conditions, especially the elderly, have increased chances of developing cancer and dying from the same. T
