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Nanoplastics have been proven to induce toxicity in diverse organisms, yet their effect on soil microbes like bacteria and fungi remains largely unexplored. In this paper, we used micro-engineered soil models to investigate the effect of polystyrene (PS) nanospheres on Pseudomonas putida and Coprinopsis cinerea. Specifically, we explored the effects of increasing concentrations of 60 nm carboxylat

Type 2 diabetes (T2D) is caused by insufficient insulin secretion from pancreatic β-cells. To identify candidates contributing to T2D pathophysiology, we studied human pancreatic islets from ~300 individuals. We found 395 differentially expressed genes (DEGs) in islets from individuals with T2D, including, to our knowledge, novel (OPRD1, PAX5, TET1) and previously identified (CHL1, GLRA1, IAPP) ca

The great variety of earth's microorganisms and their functions are attributed to the heterogeneity of their habitats, but our understanding of the impact of this heterogeneity on microbes is limited at the microscale. In this study, we tested how a gradient of spatial habitat complexity in the form of fractal mazes influenced the growth, substrate degradation, and interactions of the bacterial st

Soot, or black carbon (BC), aerosol is a major climate forcer with severe health effects. The impacts depend strongly on particle number concentration, size and mixing state. This work reports on two field campaigns at nearby urban and rural sites, 65gkm apart, in southern Sweden during late summer 2018. BC was measured using a single-particle soot photometer (SP2) and Aethalometers (AE33). Differ

An induced pluripotent stem cell (iPSC) line was generated from a 36-year-old patient with sporadic Parkinson's disease (PD). Skin fibroblasts were reprogrammed using the non-integrating Sendai virus technology to deliver OCT3/4, SOX2, c-MYC and KLF4 factors. The generated cell line (CSC-43) exhibits expression of common pluripotency markers, in vitro differentiation into three germ layers and nor

En analys av intervjuer som genomförts på Statens institutionsstyrelse LVM-hem i samband med att en person tvångsomhändertagits jmf LVM. Analysen är ett vetenskapligt underlag till SOU 2023:5 Från delar till helhet. Tvångsvården som en del av en sammanhållen och personcentrerad vårdkedja.

We present a microchannel-based adaption of density-gradient centrifugation that allows the instantaneous, precise, and repeatable generation of a 1-dimensional mass-density gradient and determination of single-cell densities with integrated mass-density calibration.

Official calls for “failed” asylum seekers to leave Sweden ignore the difficulties and harms befalling stateless people who cannot return to previous countries of residence because they lack citizenship. Stateless people are caught in limbo, a position where they have no prospects of return or of attaining a residence permit in a predictable future. To learn the underlying logics and consequences

• We aimed to capture possible insights from an AI diagnosing without human guidance.• We believe the result mainly aligns with previous knowledge. Though, vital signs and sex did not aid the AI diagnostics.

Several authors have described how the formalization of recent decades has steered doctoral education towards structured curricula, more managerial control and new models for supervision. Largely absent from these accounts, however, is if and how doctoral education has been affected by the concurrent changes in research governance, in particular by the ‘projectification’ of research. For this stud

Popular Abstract in English From everyday experience we know that water and oil do not mix. In the scientific language we say they phase separate from each other. This happens because a water molecule and an oil molecule are inherently incompatible, the former exhibiting a ‘polar’ character and the latter a ‘non-polar’ one. Water and oil molecules are small, meaning that they are made up of only The subject of this thesis is experimental investigation of self-assembly in solvent-free (ionic) macromolecular systems that contain block copolymer chains as the basic constituent component in combination with low molecular weight amphiphiles. In particular, especial attention is paid to study thoroughly a new class of block copolymer-based ionic supramolecules, named as Linear-b-AmphComb, that

Introduction and aim: In SPECT imaging, the finite spatial resolution of the imaging system leads to a blurring of the reconstructed image. Consequently, counts originating from each point in the source distribution will be spread out over a volume in the reconstructed image, leading to spill-over of counts between different structures and distortion of the apparent activity concentration. This pr

Timer options are relatively new exotic options with the feature that they expire as soon as the accumulated realized variance exceeds a predefined level. This construction leads to a random time to maturity instead of having a fixed exercise day. As shown by Bernard an Cui [7], Timer options can be priced by solving a partial differential equation or by time-changing the stock price process and t