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We have developed a method to separate bacteria from red and white blood cells (henceforth collectively called blood cells) using acoustophoresis, for subsequent PCR detection. To maximize throughput, we have now investigated the effect of increased cell concentration on the separation. Increasing the blood concentration drastically decreases bacteria recovery, but we show that this can be remedie
Lignin is the second most abundant naturally produced organic polymer on earth. Lignin‐modifying enzymes (LMEs) are produced by the white‐rot fungi as products of secondary metabolism, since lignin degradation does not provide any energy to the fungus. The main oxidative enzymes include the peroxidases‐lignin peroxidase (LiP) (diarylpropane: oxygen, hydrogen peroxide oxidoreductase), manganese per
Background:Continuous flow peritoneal dialysis (CFPD) is performed using a continuous flux of dialysis fluid via double or dual-lumen PD catheters, allowing a higher dialysate flow rate (DFR) than conventional treatments. While small clinical studies have revealed greatly improved clearances using CFPD, the inability to predict ultrafiltration (UF) may confer a risk of potentially harmful overfill
In order to characterize the radium distribution and submarine groundwater discharge (SGD) in the Bohai Sea area, the three isotopes 223Ra, 224Ra and 228Ra in different water bodies were measured in a 4-year period with the radium-delayed coincidence counting (RaDeCC) system. The results indicated that radium activities take an order of groundwater > coastal seawater > river water > central seawat
This article draws on socio-legal theory in relation to growing concerns over fairness, accountability and transparency of societally applied artificial intelligence (AI) and machine learning. The purpose is to contribute to a broad socio-legal orientation by describing legal and normative challenges posed by applied AI. To do so, the article first analyses a set of problematic cases, e.g. image rThis article draws on socio-legal theory in relation to growing concerns over fairness, accountability and transparency of societally applied artificial intelligence (AI) and machine learning. The purpose is to contribute to a broad socio-legal orientation by describing legal and normative challenges posed by applied AI. To do so, the article first analyzes a set of problematic cases, e.g., image
Philosophers’ search for the best way to explain human actions has led many to accept a core psychological model that can be supplemented by other forms of action explanation when needed. Rather than settling for this model –where everything ultimately hinges on psychologicalexplanation – this paper argues for a pluralistic view. It does not claim that the psychological view is
Inom beredskapen mot radiologiska och nukleära olyckor och katastrofer spelar strålningsmätningar en avgörande roll för att ta reda på vad som har hänt och hur farligt det är för människa, djur och natur och på vilket sätt det påverkar miljö och samhällsfunktioner. I Sverige och många andra länder i världen har allmänheten en rättighet att få reda på vad som hänt och vad de utsätts för i ett eventThis thesis describes investigations made on mobile and stationary gammaspectrometry made both under laboratory conditions and in situ. The objective hasbeen to identify and quantify radionuclides in the form of point sources,contamination and widespread deposition in situations where the measurementgeometry is not known beforehand. Both scintillators and semiconductor detectors ofsimilar size wer
These European Resuscitation Council Ethics guidelines provide evidence-based recommendations for the ethical, routine practice of resuscitation and end-of-life care of adults and children. The guideline primarily focus on major ethical practice interventions (i.e. advance directives, advance care planning, and shared decision making), decision making regarding resuscitation, education, and resear
Structural Health Information (SHI) may be provided by various sources such as e.g. structural health monitoring, inspections, testing and digital technologies and networks as by the Industry Internet of Things (HOT). SHI holds a high potential for industrial, life safety and sustainability value and facilitates an optimal and intelligent life cycle management of infrastructure and machinery syste
Brigadier General Hossein Dehghan, a commander of the Islamic Revolutionary Guard Corps, has announced his candidacy for the Iranian presidential elections in June 2021. Dehghan has a toxic military background. In the 1980s he was responsible for the vicious crackdown on opponents of the Islamic regime, and he played a central role in the bombing of the US Marine barracks in Beirut that killed hun
Fluctuating climate, heat, and drought are expected to considerably impact bread wheat (Triticum aestivum) quality in the coming years and, as wheat is an essential food element worldwide, this will have significant implications for future food security and the global economy. This leads to an urgent need for developing wheat varieties with stable yield and gluten quality. In this study, we invest
BackgroundThe risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life stress (ELS) exposure during critical periods of brain development can impact later brain function and health, including increasing the risk of developing AD. Microglial dysfunction and neuroinflammation have been implicated as playing a role in AD pathology and may be modulated
Declining bond yields and rising public debts have caused many economists to suggest raising the debt ceiling in the EU’s Stability and Growth Pact. Implicitly, they argue for replacing GDP as the anchor with the bond yield. We discuss the risks of such a shift. While such a change would provide short-term relief to highly indebted EU member states, it is based on the expectation that bond yields
Astrocytes are emerging key players in neurological disorders. However, their role in disease etiology is poorly understood owing to inaccessibility of primary human astrocytes. Pluripotent stem cell-derived cells fail to mimic age and due to their clonal origin do not mimic genetic heterogeneity of patients. In contrast, direct conversion constitutes an attractive approach to generate human astro
