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The need for modelling of materials behaviour under various mechanical conditions is driven by the evolution of computer capacity and the ability of scientists to address complex mechanical problems. Reliable models for materials behaviour, including accurate numerical values of parameters, are necessary for a continued beneficial development of the computational side of solid mechanics. High rate
While Gender studies has sometimes been placed in opposition to biomedicine and medical practices in public debate, there is increasing scholarly recognition of the relevance of social factors and relationships for biological and medical phenomena and for the quality and equity of healthcare practices (Chin et al., 2016; Meloni, Cromby, Fitzgerald, & Lloyd, 2018; SKL, 2014). In Sweden and int
BACKGROUND AND OBJECTIVES: Degarelix is a gonadotropin-releasing hormone antagonist registered for the treatment of advanced hormone-dependent prostate cancer. Treatment causing androgen deprivation is associated with QT prolongation and this study investigated whether degarelix at supratherapeutic concentrations has an intrinsic effect per se on cardiac repolarisation and the QT interval.METHODS:
Background: Traumatic brain injuries continue to be a significant cause of mortality and morbidity worldwide. Most traumatic brain injuries are classified as mild, with a low but not negligible risk of intracranial hemorrhage. To help physicians decide which patients might benefit from a computerized tomography (CT) of the head to rule out intracranial hemorrhage, several clinical decision rules h
Histological grade is one of the most commonly used prognostic factors for patients diagnosed with breast cancer. However, conventional grading has proven technically challenging, and up to 60% of the tumors are classified as histological grade 2, which represents a heterogeneous cohort less informative for clinical decision making. In an attempt to study and extend the molecular puzzle of histolo
This paper presents a dedicated search for exotic decays of the Higgs boson to a pair of new spin-zero particles, H→ aa, where the particle a decays to b-quarks and has a mass in the range of 20–60 GeV. The search is performed in events where the Higgs boson is produced in association with a W boson, giving rise to a signature of a lepton (electron or muon), missing transverse momentum, and multip
A search for the standard model Higgs boson produced in association with a vector boson with the decay H→ττ is presented. The data correspond to 20.3 fb-1 of integrated luminosity from proton-proton collisions at s=8 TeV recorded by the ATLAS experiment at the LHC during 2012. The data agree with the background expectation, and 95% confidence-level upper limits are placed on the cross section of t
Introduction Pregnancy rates after frozen embryo transfer (FET) have improved in recent years and are now approaching or even exceeding those obtained after fresh embryo transfer. This is partly due to improved laboratory techniques, but may also be caused by a more physiological hormonal and endometrial environment in FET cycles. Furthermore, the risk of ovarian hyperstimulation syndrome is pract
Cardiovascular diseases are among the most important causes of death in thedeveloped countries. These diseases are partly caused by too high cholesterolconcentrations in the blood. Avena sativa, oat, is the most common spieces of the genus Avena, and produced in huge amounts worldwide. Oats have been shown to have cholesterol-lowering properties since the 1960s. This property was originally attrib
Spatial models, such as the Besag, York and Mollie (BYM)model, have long been used in epidemiology and disease mapping. A commonproblem in these subjects is the modelling of number of disease eventsper region; here the BYM models provides a holistic framework for bothcovariates and dependencies between regions.We use these tools to assess the relative insurance risk associated withthe policyholder
Objective To explore healthcare providers’ perceptions of the current postpartum care (PPC) practice and its potential for improvement at governmental health institutions in low-resource suburbs in Dar es Salaam, Tanzania. Design Qualitative design, using focus group discussions (8) and qualitative content analysis. Setting Healthcare institutions (8) at three levels of governmental healthcare in
Due to the global demographic change many more people will need to work until anolder age, and organisations and enterprises need to implement measures to facilitate an extendedworking life. The aim of this study was to investigate organisational measures and suggestionsto promote and make improvements for a healthy and sustainable working life for all ages in anextended working life. This is a qu
A search for new phenomena with top quark pairs in final states with one isolated electron or muon, multiple jets, and large missing transverse momentum is performed. Signal regions are designed to search for two-, three-, and four-body decays of the directly pair-produced supersymmetric partner of the top quark (stop). Additional signal regions are designed specifically to search for spin-0 media
BackgroundGraft-contaminating tumor cells correlate with inferior outcome in high-risk neuroblastoma patients undergoing hematopoietic stem cell transplantation and can contribute to relapse. Motivated by the potential therapeutic benefit of tumor cell removal as well as the high prognostic and diagnostic value of isolated circulating tumor cells from stem cell grafts, we established a label-free
A search for heavy resonances decaying into a W or Z boson and a Higgs boson produced in proton-proton collisions at the Large Hadron Collider at s=13 TeV is presented. The analysis utilizes the dominant W→qq¯′ or Z→qq¯ and H→bb¯ decays with substructure techniques applied to large-radius jets. A sample corresponding to an integrated luminosity of 139 fb-1 collected with the ATLAS detector is anal
Most developments in regenerative medicine have in common that there are many uncertainties and knowledge gaps. These features make the evaluation of long-term consequences of the available options difficult and have consequences for the ethical issues raised. This paper presents an overview of ethical issues raised in regenerative medicine, using as a starting point a list of stakeholders and the
ObjectiveWe investigate the association between the geographic proximity of the grandparents on net marital fertility and maternal survival in Sweden, 1900–1910, within the framework of the cooperative-breeding-hypothesis.MethodsData were derived from Swedish full-count censuses (1880–1910) and the Swedish Death Index. Married couples were linked to their parental households. Poisson and logistic
