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In an effort to bioengineer elastomeric particles (EPs), with negative acoustic contrast factor, to capture cells, we have successfully functionalized EPs with anti-human CD45 antibodies that enable capturing of WBCs from human RBC lysed blood samples. We demonstrate that the negative selection of WBCs with EPs and acoustophoresis can be employed to reduce WBC contamination while enriching label-f
Purpose: The eyelid is commonly dissected and divided in the process of, for example, blepharotomy, entropion repair, or when preparing a full-thickness eyelid flap to reconstruct a tumor defect. No study has yet been conducted to examine how perfusion in an eyelid is affected by dissection, using modern imaging techniques. Methods: The eyelid was divided with a 10-mm vertical incision, 5 mm from
Context: Residential care homes (RCHs) are a common place of death. Previous studies have reported a high prevalence of symptoms such as pain and shortness of breath among residents in the last week of life. Objectives: The aim of the study was to explore the presence of symptoms and symptom relief and identify factors associated with symptom relief of pain, nausea, anxiety, and shortness of breat
Sustainability science emerged as a new academic field to address complex sustainability challenges. To train sustainability experts, sustainability science programs and sustainability-focused courses are offered in higher education, especially at the graduate level. Given the diverse topics and the complex structures of sustainability challenges, what are the required knowledge and skills needed
Accelerated cell aging, indexed in peripheral leukocytes by telomere shortness and in peripheral blood mononuclear cells (PBMCs) by telomerase activity, has been reported in several studies of major depressive disorder (MDD). However, the relevance of these peripheral measures for brain indices that are presumably more directly related to MDD pathophysiology is unknown. In this study, we explored
Germ layer formation and primary axis development rely on Fibroblast growth factors (FGFs). In Xenopus, the secreted serine protease HtrA1 induces mesoderm and posterior trunk/tail structures by facilitating the spread of FGF signals. Here, we show that the serpin Protease nexin-1 (PN1) is transcriptionally activated by FGF signals, suppresses mesoderm and promotes head development in mRNA-injecte
Occupational safety and health (OSH) is a vital part of the right to health. While the International Labor Organization (ILO) historically treated OSH as an entirely technical matter, it has increasingly been influenced by a human rights agenda. The ILO has responded by adopting and promoting a large number of international standards-in the form of conventions, recommendations, and codes of practi
OBJECTIVE: Cardiovascular disease (CVD) risk prediction represents an increasing clinical challenge in the treatment of diabetes. We used a panel of vascular imaging, functional assessments, and biomarkers reflecting different disease mechanisms to identify clinically useful markers of risk for cardiovascular (CV) events in subjects with type 2 diabetes (T2D) with or without manifest CVD.RESEARCH
Background: Information is scarce on long-term changes in energy intake (EI), dietary energy density (DED), and body composition in adolescents undergoing laparoscopic Roux-en-Y gastric bypass (RYGB). Objectives: To investigate long-term changes in EI, DED, and body composition in adolescents after LRYGB. Setting: University hospitals, multicenter study, Sweden. Methods: Eighty-five adolescents (6
The aim of the current retrospective study was to investigate the subjective experience of momentum and the presence of momentum in performance. Earlier studies have focused on studying individuals and novices in fictive situations. We decided to study the phenomenon on a team level. A case study was conducted on ten female elite handball players who were asked to carry out a survey where the aim
The thesis investigates lung function and the effects of rescue surfactant treatment in mechanically ventilated preterm human infants with respiratory distress syndrome (RDS), and the effects of ventilation at birth on the response to surfactant supplementation in preterm lambs. To assess lung function, the author recorded static pressure-volume (P-V) curves during passive deflation from total lun
BACKGROUND: /st>Previous research suggests that the World Health Organization Surgical Safety Checklist time-out reduces communication failures and medical complications and supports development of better safety attitudes. Previous research also indicates that different values can affect the implementation of interventions. OBJECTIVE: /st>To investigate the actual usage of the checklist in practic
I juni 2011 antog ILO konventionen om goda villkor för hushållsarbetare. Konventionen fastställer anställningsvillkor och arbetsrättigheter för hushållsarbetare. Hushållsarbete sker, till skillnad från andra former av arbete, i privata hem utan insyn från det offentliga och är ofta ett ensamarbete. Detta innebär att hushållsarbetare riskerar att bli utsatta för missförhållanden och exploatering. KIn June 2011, the Domestic Workers Convention was adopted in the ILO. The Convention establishes minimum conditions of employment and labour rights for domestic workers. In contrast to other types of work, domestic work takes place in private households, in isolation and hidden from public insight. This makes domestic workers vulnerable to abuse and exploitation. The Domestic Workers Convention ob
A real-time optical imaging system has been developed and commissioned at the European Spallation Source (ESS) to monitor the high-power proton beam at the tuning beam dump, and provide machine protection. The system employs chromium-doped alumina (Chromox) luminescent screens imaged by radiation-shielded optics and a CMOS camera. Real-time FPGA-based processing extracts beam size and position, de
Swedish tragedies from the first half of the eighteenth century often looked at French drama, but there are notable instances where inspiration seems to have come from elsewhere: Erik Wrangel’s Torilla (1738), for example, breaks conventions expected of French theatre by letting princes battle supernatural forces on stage; the story presented in Eric Brander’s Cleopatra (1749) seems familiar from
The EU's Clean Energy Package introduced renewable and citizen energy communities (RECs/CECs) to strengthen citizen participation in electricity markets. Nordic countries, however, have long-standing traditions of community-based energy provision, including district heating cooperatives, small hydropower schemes, and wind cooperatives. This article examines how nationally embedded energy models in
To avoid discomfort, health care professionals may hesitate to pursue conversations about end of life with patients. Certain tools have the potential to facilitate smoother conversations in this matter. The objective was to explore the experiences of patients in palliative care in using statement cards to talk about their wishes and priorities. Forty-six cards with statements of wishes and priorit
