Filetype
Climatic factors and water and land use management mainly impact dust storm frequency and intensity. Water scarcity and a drier climate will lead to more severe and frequent dust storms in the near and far future. This makes dust storm susceptibility a dynamic phenomenon requiring spatiotemporal analyses. Regarding the complexity of this phenomenon, this chapter discusses AI-based methods for spat
Microplastics and nanoplastics (MNPs) are ubiquitous environmental pollutants with increasing implications for human health. While their presence in human tissues is established, the molecular mechanisms driving their potential neurotoxicity remain unclear. This study investigates the impact of polystyrene (PS) on amyloid protein misfolding and cellular metabolism using Optical Photothermal Infrar
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants remain inadequately understood. In this study, we report a genome-wide association study of HF and its subtypes in a sample of 1.9 million individuals. A total of 153,174 individual
Transplantation of human fetal ventral mesencephalic tissue in individuals with Parkinson's disease has yielded clinical benefits but also side effects, such as graft-induced dyskinesias. The open-label TransEuro trial ( NCT01898390 ) was designed to determine whether this approach could be further developed into a clinically useful treatment. Owing to poor availability of human fetal ventral mese
Climate change is increasingly recognized as a major security concern, with drought–migration–conflict linkages attracting significant attention in both policy and research. While some narratives portray drought as a direct driver of migration and conflict, evidence shows a far more complex relationship: climate stress can lead to more migration in some contexts and less in others, with internal m
Lipid nanoparticles (LNPs) are clinically approved for mRNA-based vaccines and liver-targeted siRNA delivery. However, poor nucleic acid delivery efficiency limits their application in extrahepatic tissues and tumors. Here, using live-cell and super-resolution microscopy, we identify multiple distinct steps of inefficiencies in the cytosolic delivery of both siRNA and mRNA cargoes. Membrane damage
FPRA112 praktisk informationVT14 ALLMÄN INFORMATION FRITS GÅVERTSSON FILOSOFISKA INSTITUTIONEN, LUNDS UNIVERSITET Rum 312 Kungshuset, Lundagård, 222 22 Lund, SWEDEN e-mail: frits.gavertsson@fil.lu.se tel:+46768482707 Praktisk filosofi ht-13 FPRA11:2 (Kritiskt tänkande i värdefrågor) Datum Tid Sal Föreläsning Läsanvisningar 24/2 11-13 Jos: 314 1: Introduktion Kap. 1-2 Logisk tänkande & Definiti
https://www.fil.lu.se/media/utbildning/dokument/kurser/FPRA11/20141/FPRA112_praktisk_informationVT14.pdf - 2026-07-21
Lönesamtal | Akademikerföreningen vid Siemens Energy AB Hoppa till huvudinnehåll Öppna sökruta Öppna Huvudmeny Sök på saco.se Om oss Stadgar Kollektivavtal Bli medlem Nyheter Nyhetsbrev Kaffekampanj Presentation "Will I be poor when I retire" Löneskola 2026 Lecture "Swedish pension system", 15th of April 11:45 Lecture "Working in Sweden" 16th of December Presentationsmaterialet från pensionsförelä
Lokalt samarbetsavtal för AkademikerAlliansen i XX kommun Detta samarbetsavtal avser lokal samverkan mellan de förbund inom AkademikerAlliansen som väljer teckna detta avtal. 1.0 Ändamål 1.1 Avtalets syfte är att reglera förutsättningarna som ska gälla mellan de förbund som ingår i föreningen. 2.0 Bildande av den lokala föreningen 2.1 Utgångspunkten för att bilda lokal förening är att det är frivi
Long interspersed nuclear element 1 (L1) retrotransposons represent a vast source of genetic variability. However, mechanistic analysis of whether and how L1s contribute to human developmental programs is lacking, in part due to the challenges associated with specific profiling and manipulation of human L1 expression. Here, we show that thousands of hominoid-specific L1 integrants are expressed in
Purpose: Glomerular filtration rate (GFR) is used to evaluate kidney function. Creatinine and cystatin C levels C are the two endogenous substances used to estimate GFR (eGFRCR and eGFRCYS). Agreement between the two is reflected by the eGFRCYS/eGFRCR-ratio, and an eGFRCYS/eGFRCR-ratio <0.70 is strongly associated with mortality and morbidity. An explanation is a selective decrease in the filtrati
Boreal forests are globally important carbon (C) sinks, but strategies for maximising their climate benefit remain under debate. Major uncertainties in this discussion arise from contrasting sink-source estimates, which largely emanate from inherent limitations of standard measurement techniques to distinct spatio-temporal scales. Here, we use a spatially-nested measurement framework that integrat
Understanding the dynamics of post-fire carbon recovery is critical for managing boreal forests under climate change. This study evaluates the LPJ-GUESS-BLAZE models’ performance in simulating vegetation structure, fire emissions, and post-fire carbon dynamics at the stand scale in a boreal forest in Sweden. Combining current climate and future scenarios (SSP1–2.6, SSP5–8.5), we investigated the i
Background: Stable atherosclerotic plaques are characterized by thick fibrous caps of smooth muscle cells, collagen, and macrocalcifications. Identifying factors of plaque stability is necessary to design drugs to prevent plaque rupture and symptoms. Osteomodulin, originally identified in bones, is expressed by bone synthesizing osteoblasts and involved in mineralization. In the present study, we
The human forebrain has expanded in size and complexity compared to chimpanzees despite limited changes in protein-coding genes, suggesting that gene expression regulation is an important driver of brain evolution. Here, we identify a KRAB-ZFP transcription factor, ZNF558, that is expressed in human but not chimpanzee forebrain neural progenitor cells. ZNF558 evolved as a suppressor of LINE-1 tran
Introduction: The use of medications in the general population has increased over time. Information on active metabolite concentrations for common drugs in the general population is limited. Recent advances in metabolomic technologies have made high-throughput profiling of many active metabolites in large epidemiological cohorts increasingly feasible.Aim: 1. Prospective assessment of the proportio
Variation of the blood content of the pulmonary vascular bed during a heartbeat can be quantified by pulmonary blood volume variation (PBVV) using magnetic resonance imaging (MRI). The aim was to evaluate if PBVV differs in patients with heart failure compared to healthy controls and investigate the mechanisms behind the PBVV. Forty-six patients and 10 controls underwent MRI. PBVV was calculated f
We report a new design of an acoustophoretic trapping device with significantly increased capacity and throughput, compared to current commercial acoustic trapping systems. Acoustic trapping enables nanoparticle and extracellular vesicle (EV) enrichment without ultracentrifugation. Current commercial acoustic trapping technology uses an acoustic single-node resonance and typically operates at flow
