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The thesis starts with a description of the background to the change of the rules on deduction of VAT on mixed use immovable property through the insertion of Article 168a in the RVD. The reason according to the Amendment is to promote equity and to prevent unjustified cash-flow advantages granted to taxable persons who use acquire immovable property, deduct full input VAT and then pay it back o
Extracellular vesicles (EVs) are derived from the membrane of platelets and released in the circulation upon activation or injury. Analogous to the parent cell, platelet derived EVs play an important role in hemostasis and immune responses by transfer of bioactive cargo from the parent cells. Platelet activation and release of EVs increases in several pathological inflammatory diseases, such as se
Immunotherapy is revolutionizing cancer treatment, but success is limited to a fraction of patients. Tumor immunosurveillance and immunotherapy relies on presentation of tumor-associated antigens by conventional dendritic cells type 1 (cDC1). However, tumors develop mechanisms to avoid immune recognition such as downregulation of antigen presentation and exclusion of cDC1. We have previously demon
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes1. Here, using data from a genome-wide association study of 5.4 million individuals of diverse ancestries, we show that 12,111 independent SNPs that are significantly associated wit
I ett barnahus samverkar olika myndigheter för att samordna utredningar som startas då det finns misstanke om brott mot barn. Målet är att samverkan ska leda till ett barnanpassat utredningsförfarande och ett bättre underlag för rättsprocessen. I denna bok beskrivs de barn som misstänks ha varit utsatta för brott, vem som är misstänkt förövare och vilken typ av brott som barnen misstänks ha varit
Immunotherapy has shown limited success in acute myeloid leukemia (AML), indicating an incomplete understanding of the underlying immunoregulatory mechanisms. Here we identify an immune evasion mechanism present in 60% of AML cases, wherein primitive AML cells aberrantly express the lymphoid surface protein SLAMF6 (signaling lymphocyte activation molecule family member 6). Knockout of SLAMF6 in AM
In North and East Syria—also known as Rojava—the convergence of war, politics, and environmental challenges presents a complex and pressing reality. This blog is dedicated to exploring these interlinked issues, highlighting how conflict and ecological degradation are deeply connected, and how these dynamics affect communities in varied and unequal ways.
This study investigated the spatial dynamics of bark beetle infestations and their relationships with risk factors in south-eastern Swedish forests during the years 2018–2020, highlighting the importance of spatial heterogeneity of risk factors, particularly under climate change. First, global Random Forest (RF) models were developed to examine the relationships between bark beetle infestations an
BACKGROUND: Lung transplantation remains hampered by a scarcity of viable donor lungs, partially attributed to donor lung injuries.METHODS: Three porcine lung injury models were studied: infection-induced using lipopolysaccharide (n = 7), aspiration-induced using endotracheal gastric content (n = 7), and injury using lavage and harmful ventilation (ventilator-induced lung injury; n = 7). Molecular
Soil microbes play an important role in governing global processes such as carbon cycling, but it is challenging to study them embedded in their natural environment and at the single cell level due to the opaque nature of the soil. Nonetheless, progress has been achieved in recent years towards visualizing microbial activities and organo-mineral interaction at the pore scale, especially thanks to
We present the use of a high capacity and high throughput acoustic trapping platform for phenotypic characterization and functional studies of extracellular vesicles (EVs) from pathogen activated platelets. Platelet rich plasma was stimulated with bacterial M1 protein isolated from S. Pyogenes, which is known to activate platelets. The subsequently released platelet EVs were isolated from 400 μL p
The toxicity of particulate matter (PM) is dependent on particle physical and chemical properties and is commonly studied using in vivo and in vitro approaches. PM to be used for in vivo and in vitro studies is often collected on filters and then extracted from the filter surface using a solvent. During extraction and further PM sample handling, particle properties change, but this is often neglec
BACKGROUND: A hydraulic force generated by blood moving the atrio-ventricular plane is a novel mechanism of diastolic function. The direction and magnitude of the force is dependent on the geometrical relationship between the left atrium and ventricle and is measured as the short-axis atrio-ventricular area difference (AVAD). In short, the net hydraulic force acts from a larger area towards a smal
Climate change and connected environmental disruptions have a large negativeeffect on the health of humans and other species. Improved understanding ofknown links in the environment-disease nexus as well as knowledge gaps isessential to prepare for and mitigate this escalating threat. However, knowledgefragments are scattered across millions of scientific articles making informationsynthesis too c
PURPOSE: To estimate the effect of dexamethasone eye drops on the risk of progression from type 2 retinopathy of prematurity (ROP) to ROP requiring traditional treatments.DESIGN: Register-based cohort study.PARTICIPANTS: Preterm infants born before 30 weeks' gestation from 2015-2018 (control years) and from 2020-2021 (intervention years) registered in the Swedish Quality Register for ROP at 4 Swed
Aim: Allometric relationships, which describe plant growth patterns shaped by environmental conditions, reflect functional trade-offs and represent key functional traits that optimise adaptation, resource acquisition, stress tolerance and competition. Here, we assess how these allometric relationships and associated functional trade-offs drive ecosystem structure, functioning and competitive inter
Litteraturlista för GEL303 Klimatologi och geomorfologi, 10 poäng Litteraturlista för GEOB03 Geologi: Litosfären, 15 högskolepoäng (Geology: The Lithosphere, 15 ECTS credits) Fastställd av studierektor den 21 januari 2013 (på delegation enligt institutionsstyrelsens förslag den 5 februari 2010) Författare & titel (ev. tidskrift, serie, etc.) B,I,L (*) Sidor som skall läsas, Anmärkningar (**) Klein
https://www.geologi.lu.se/sites/geologi.lu.se/files/geob03-kursplan.pdf - 2026-07-23
(Microsoft Word - GEOC02 prelimin\344r kurslitteraturlista.docx) Litteraturlista för GEOC02 Medicinsk geologi, 7,5 högskolepoäng (Medical Geology, 7.5 ECTS credits) Författare & titel (ev. tidskrift, serie, etc.) B,I,L (*) Sidor som skall läsas, Anmärkning, (**) Selinus, O. (red): Medicinsk geologi. Studentlitteratur, 2010. ISBN 978-91-44-05448-3 Enligt anvisningar som ges vid kursstart Åhörarkopi
https://www.geologi.lu.se/sites/geologi.lu.se/files/geoc02-kursplan.pdf - 2026-07-23
