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Video capsule endoscopy (VCE), perfomed by ingesting a small vitamin-sized camera pill, was developed over a period of a couple of decades and –since its introduction in clinical practice at the dawn of the millennium– has become an essential tool in the diagnosis and management of small bowel (SB) diseases. At the same time, other fields such as minimally invasive diagnosis of other parts of the
Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac
Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.
Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri
The present article describes data from pilot studies with the Swedish versions of the Mindful Attention Awareness Scale (MAAS) and the Kentucky Inventory of Mindfulness Skills (KIMS). The MAAS and two of the KIMS scales, Act with Awareness and Accept without Judgment, were found to correlate in the predicted direction with measures of well-being and emotional distress. The KIMS scales Observe and
Presented here is an engineered protein domain, based on Protein A, that displays a calcium-dependent binding to antibodies. This protein, ZCa, is shown to efficiently function as an affinity ligand for mild purification of antibodies through elution with ethylenediaminetetraacetic acid. Antibodies are commonly used tools in the area of biological sciences and as therapeutics, and the most commonl
2023-09-25 Protokoll LSK Sida 1 av 5 Lokal skyddskommitté PROTOKOLL Diarienummer V 2023/2095 Datum 2023-09-25 Protokoll lokal skyddskommitté Närvarande Karin Hall, stf ordförande Catrin Malmström, kansli N, ledamot Jessica Abbott, biologiska institutionen, ledamot Leif Bülow, kemiska institutionen, ledamot Magnus Alsterfjord, huvudskyddsombud Bengt Meuller, över- och huvudskyddsombud Carina Rasmus
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. One of the hallmarks of the disease is a multitude of autoantibodies, indicating a breakdown in self tolerance. The corresponding antigens have been fou
Presentation template with LiU typography The management of enhancement requests – a customer perspective EBSCO Systems Swedish User Group Annual meeting 2023 Eva Sejmyr, Senior Librarian and System Manager, Linköping University Library Let's explore the management of enhancement requests from a customer perspective, with examples from Linköping University Library and ESSUG. 2023-04-26The manageme
https://www.ub.lu.se/sites/ub.lu.se/files/2023-05/Enhancement%20requests%202023.pdf - 2026-04-22
Varför gör vissa bakterier oss sjuka men inte andra? Hur kommer det sig att vissa bakterier lyckas överleva och infektera särskilda delar av kroppen men väldigt sällan andra? Bakterier och människor har evolverat länge tillsammans och har därmed lyckats utveckla specifika angrepps och försvarsmekanismer mot varandra. Det är känt sedan tidigare att några bakterier uttrycker proteiner med förmågan Bacteria and humans have co-evolved since their common existence. They have thereby developed very specific defence and target mechanisms against one another. Understanding the complex biomolecular processes behind these interactions can be of great use for developing treatments against bacterial diseases. The aim of this thesis project was to verify, and introduce a model for understanding, the i
