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The role of cholesterol differs in the two compartments of the testis. In the interstitial tissue, cholesterol is necessary for the synthesis of testosterone, whereas in the seminiferous tubules, membrane cholesterol content in developing germ cells will influence the gametes' fertility. Here we evaluate the hormone-sensitive lipase (HSL) modulation of the cholesterol metabolism in each compartmen

The present work reports on testicular hormone-sensitive lipase (HSL), the biological significance of which has been documented in male fertility. The HSL protein levels and enzymatic activity were measured, respectively, by densitometry of immunoreactive bands in Western blots, performed with antibodies against recombinant rat HSL, and by spectrophotometry in seminiferous tubules (STf) and inters

Dysfunction in various parts of immune defence, such as immune response, immune complex clearance, and inflammation, has an impact on pathogenesis in systemic lupus erythematosus (SLE). We hypothesised that combinations of common variants of genes involved in these immune functions are associated with susceptibility to SLE. The following variants were analysed: HLA DR3, HLA DQ2, C4AQ0, Fcgamma rec

https://www.lu.se/evenemang/75-phd-seminar-tanja-hylling-diers-who-cares-embodied-practice-caring-and-listening - 2025-11-08

https://www.mcc.lu.se/sites/mcc.lu.se/files/info_och_ansokan_om_apparatanslag_fran_malmo_cancer_center_2019.pdf - 2025-11-08

Protein MIG, from Streptococcus dysgalactiae, binds alpha2-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000- fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variation in the IgG-binding repeats was recognized. Protein MIG interacted with goat IgG1 via both the

Museum Stobaeanum included a collection of artefacts, originally labeled ”artificialia”. It consisted primarily of ethnographic objects from Asia, North and South America, Russia, Siberia, Greenland and Lapland, but also Classical antiquities, Nordic antiques, curious European works of art, as well as scientific instruments and models. Museum Stobaeanum included a comparatively small collection of

https://www.historiskamuseet.lu.se/stobaeus-project/artefacts - 2025-11-07

Sektionen HR har tagit fram ett universitetsgemensamt stöd i form av en årscykel för bisyssla. Genväg:Ta del av årshjulets olika steg i löptext Årscykelns olika stegJanuariUppstart årlig anmälningsskyldighet för lärare – under första kvartalet.Information till prefekter och lärare om att bisyssla ska anmälas senast 31 mars. Hantering av anmälningar och eventuella beslut om upphörande av bisyssla.F

https://www.hr-webben.lu.se/arscykel-bisyssla - 2025-11-07

Bisyssla årshjul Årshjul bisyssla Jan Mar Apr Maj JuniJuli Aug Sept Okt Nov Dec Feb JANUARI • Uppstart årlig anmälningsskyldighet för lärare - under första kvartalet • Information till prefekter och lärare om att bisyssla ska anmälas senast 31/3. Information ges b.la via HR/chefs nytt, i Primula, LU-nytt och i informationsbrev från prefekt till lärare. • Hantering av anmälningar och ev beslut om u

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2024-08/Bisyssla%C3%85rshjul_240709.pdf - 2025-11-08

Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP-induced acute liver injury (APAP-ALI) and justifies development of anti-inflammatory therapies with therapeutic efficacy beyond the therapeutic window of the only current treatment option, N-acetylcysteine (NAC). The inflammatory mediator, h

Ändrade levnadsvanor i västerländska länder har lett till en ökning av sjukdomar så som IBS, infektioner i mag- och tarmkanal och allergier. Det har dessutom observerats att mikrofloran förändrats och goda bakterier så som Limosilactobacillus reuteri försvunnit. Mag- och tarmkanalen har därmed förlorat sina goda soldater mot patogena fiender med dysfunktionell balans som resultat. Därför är det inThis master thesis work was performed in collaboration with BioGaia AB, a Swedish biotech- company producing probiotic supplements containing the bacteria Limosilactobacillus reuteri. The products provided by BioGaia contain live microorganisms. Therefore, a method suitable for the correct enumeration of living cells is crucial in probiotic samples and today the so-called plate count method is use