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In addition to its well-known hematopoietic effects, erythropoietin (EPO) also has neuroprotective properties. However, hematopoietic side effects are unwanted for neuroprotection, underlining the need for EPO-like compounds with selective neuroprotective actions. One such compound, devoid of hematopoietic bioactivity, is the chemically modified, EPO-derivative carbamylerythropoietin (CEPO). For c

Lipids have been implicated in beta-cell stimulus-secretion coupling. In such a role, lipases in beta-cells would be required to generate lipid coupling factors. We have shown previously that glucose stimulates lipolysis in rodent islets. In addition, lipolysis and diacylglycerol lipase activity in islets are abolished by orlistat, an irreversible lipase inhibitor with a broad specificity for subs

The ease and abundance of knowledge acquisition that is unparalleled in history, renders knowledge transition and practicing of skills in education insufficient. The importance of personal reflection and identity, i.e. the individual’s mindset, is increasingly important. Re-thinking educational approaches, to entrepreneurship and leadership in particular, is important since they are activities for

The Lorentzian lifetime widths of the 4d and 4f levels in the sixth-period elements W74 to Bi83 have been measured using photoelectron spectroscopy. A compilation of 4f-level widths from the literature is also made. The general trend of the 4f-level widths is well reproduced by McGuires calculations, although the absolute widths seem to be underestimated. The 4d5/2-level width shows a remarkable c

The Genographic Project is an international effort aimed at charting human migratory history. The project is nonprofit and nonmedical, and, through its Legacy Fund, supports locally led efforts to preserve indigenous and traditional cultures. Although the first phase of the project was focused on uniparentally inherited markers on the Y-chromosome and mitochondrial DNA (mtDNA), the current phase f

Objectives: Evaluate if socioecological and biological factors, at the age of 8 years, are associated with lower level of physical activity (PA) 2 years later. Method: In a study cohort of 199 children aged 7.8±0.6 years, we used questionnaires and physical measurements to evaluate biological (eg, sex), social (eg, parental PA) and environmental (eg, school settings) factors. Objective PA was meas

BACKGROUND: The incidence of skin diseases in children is influenced by hereditary, social, and environmental factors. The objective of this study was to determine the incidence of pediatric dermatoses at a University Hospital in Northern Greece.PATIENTS AND METHODS: We reviewed epidemiologic data of 940 patients, aged 0-18 years, who were referred to the outpatient clinic of a University Hospital

Marine macroalgal (seaweed) polysaccharides are highly promising for next-generation applications in several industries. However, despite the reported comprehensive potential of these polysaccharides, commercial products are scarce on the market. Seaweed cultivations are increasing in number and production quantity, owing to an elevated global trend of utilization interest in seaweed. The extracti

Cell-replacement therapies have long been an attractive prospect for treating Parkinson disease. However, the outcomes of fetal tissue-derived cell transplants in individuals with Parkinson disease have been variable, in part owing to the limitations of fetal tissue as a cell source, relating to its availability and the lack of possibility for standardization and to variation in methods. Advances

The management of non-muscle-invasive bladder cancer (NMIBC) has evolved from the first reports on bladder endoscopy and transurethral resection to the introduction of adjuvant intravesical treatment. However, disease recurrence and progression remain an ongoing risk, placing a heavy burden on healthcare resources and on patients’ quality of life. Deeper understanding of the molecular basis of the

This thesis analyses the question of the right to compensation for victims of racial discrimination. The purpose is first of all to determine whether or not victims of racial discrimination have a right to compensation under international human rights law and to establish the content and limits of such a right. In order to achieve this purpose four specific questions are examined, namely: 1. Is th

Companies share their intellectual property with potential competitors in many different ways, including patent pooling. A patent pool is an agreement between two or more patent owners to license one or more of their patents to one another or to third parties. In Europe the Commission used the term patent pool as the bringing together of the patents of two companies, which makes it available for u