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Quantum annealing is a promising approach for obtaining good approximate solutions to difficult optimization problems. Folding a protein sequence into its minimum-energy structure represents such a problem. For testing new algorithms and technologies for this task, the minimal lattice-based [hydrophobic (H) or polar (P) beads] HP model is well suited, as it represents a considerable challenge desp
We use Markov state models (MSMs) to analyze the dynamics of a β-hairpin-forming peptide in Monte Carlo (MC) simulations with interacting protein crowders, for two different types of crowder proteins [bovine pancreatic trypsin inhibitor (BPTI) and GB1]. In these systems, at the temperature used, the peptide can be folded or unfolded and bound or unbound to crowder molecules. Four or five major fre
Time-dependent ensemble averages, i.e., trajectory-based averages of some observable, are of importance in many fields of science. A crucial objective when interpreting such data is to fit these averages (for instance, squared displacements) with a function and extract parameters (such as diffusion constants). A commonly overlooked challenge in such function fitting procedures is that fluctuations
Abstract:This doctoral thesis is addresses two topics in integrated circuit design: multiband direct conversion cellular receivers for cellular frequencies and beam steering transmitters for millimeter wave communication for the cellular backhaul. The trend towards cellular terminals supporting ever more different frequency bands has resulted in complex radio frontends with a large number of RF in
The present study examined the agreement between single and multiple sample plasma clearance of iohexol, a non-ionic contrast agent, in renal failure. Sixty-five patients with varying degree of renal insufficiency received 10 ml iohexol (300 mg I/ml) i.v. and plasma samples were collected four times during the following 3-24 h. Plasma-iodine concentrations were determined by X-ray fluorescence. Pr
The vehicle-estimation problem is approached by fusing measurements from wheel encoders, an inertial measurement unit, and (optionally) a global positioning system in a Rao-Blackwellized particle filter. In total 14 states are estimated, including key variables in active safety systems, such as longitudinal velocity, roll angle, and wheel slip for all four wheels. The method only relies on kinemat
Urak Lawoi är en ursprungsbefolkning i Andamansjön som bl.a. bor på kända turistöar som Phuket, Phi Phi, Ko Lanta Yai och Ko Lipe utanför Thailands västkust. Deras språk och kultur skiljer sig från övriga thailändares, inte minst ifråga om kunskap att navigera på havet. Att bo på eller vid havet är centralt för deras identitet; det är där de fiskar, samlar föda på stränder och utför sina ritualer.
There has been little interest in the longitudinal movement of the arterial wall. It has been assumed that this movement is negligible compared with the diameter change. Using a new high-resolution noninvasive ultrasonic method, we measured longitudinal movements and diameter change of the common carotid artery of 10 healthy humans. During the cardiac cycle, a distinct bidirectional longitudinal m
We study the joint design of optimal linear MIMO encoders and decoders for filtering and transmission of a vector- valued signal over parallel Gaussian channels subject to a real- time constraint. The objective is to minimize the sum of the estimation error variances at the receiving end. The design problem is nonconvex, but it is shown that a global optimum can be found by solving a related two-s
This study analyses the constitutive power of narratives in relation to a retroliberal paradigm shift in EU development policy by focusing on blended finance targeting sub-Saharan Africa. This study builds on the claims of Mawdsley (2015) that a reconfiguration of global development policy has challenged the North ontologically, which have been accompanied with the emergence of retroliberalism. Th
We study geometric reconstruction problems in one-dimensional retina vision. In such problems, the scene is modeled as a two-dimensional plane, and the camera sensor produces one-dimensional images of the scene. Our main contribution is an efficient method for computing the global optimum to the structure and motion problem with respect to the L-infinity norm of the reprojection errors. One-dimens
Abstract in UndeterminedIn this paper, a number of channel estimation algorithms for iterative receivers are compared for the case of an up-link orthogonal frequency division multiplexing interleave division multiple access (OFDM-IDMA) system. Both pilot based algorithms, used to obtain an initial estimate, as well as semi-blind decision-directed algorithms working as a component of the iterative
Computer simulation can provide valuable insight into the forces driving biomolecular liquid-liquid phase separation. However, the simulated systems have a limited size, which makes it important to minimize and control finite-size effects. Here, using a phenomenological free-energy ansatz, we investigate how the single-phase densities observed in a canonical system under coexistence conditions dep
In this paper, a novel decentralized leader-follower control scheme for multi–agent systems is devised, where each agent communicates only with a subset of neighboring mates. The goal is to track assigned trajectories for the centroid and the formation of the system. The desired trajectories are known only by a subset of agents, named leaders: the other agents, the followers, are required to estim
Symmetry and dominance breaking can be crucial for solving hard combinatorial search and optimisation problems, but the correctness of these techniques sometimes relies on subtle arguments. For this reason, it is desirable to produce efficient, machine-verifiable certificates that solutions have been computed correctly. Building on the cutting planes proof system, we develop a certification method
Permafrost regions contain approximately half of the carbon stored in land ecosystems and have warmed at least twice as much as any other biome. This warming has influenced vegetation activity, leading to changes in plant composition, physiology, and biomass storage in aboveground and belowground components, ultimately impacting ecosystem carbon balance. Yet, little is known about the causes and m
