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Human Fetal Hemoglobin : Biochemical Characterization and Recombinant Production

Blood transfusion is a common medical procedure when oxygen supply in the body is impaired. However, blood transfusion is not always without risks. The uncontrolled spreading of blood borne pathogens such as HIV or hepatitis B and C virus has urged researchers to look for “blood substitutes”. Many research groups have put their focuses on hemoglobin-based products (HBOCs). The major source of haem

Rewards to skill supply, skill demand and skill match-mismatch: Studies using the Adult Literacy and Lifeskills survey

This thesis is a collection of three independent but closely related studies. The focus is on the potential causes of skill mismatch, the extent of skill mismatch, the socio-demographic make-up of skill mismatch, and the consequences of skill mismatch in terms of earnings as well as employer sponsored adult education/training. A distinction is made between skill mismatch and education mismatch. Al

Characterization of Membrane Proteins: From a gated plant aquaporin to animal ion channel receptors

Membrane proteins play several important roles in a cell. Among these proteins are aquaporins (AQPs) and transient receptor potential (TRP) ion channels that mediate water transport, temperature and noxious chemical sensation, respectively. The function of some AQPs, for example the spinach isoform SoPIP2;1 is regulated by pH, phosphorylation and heavy metals such as mercury. However, the mechanis

Nutrient recovery from waste streams through struvite formation

Popular Abstract in English These days we hear a lot about sustainability and most of us try to live in a more sustainable way. We use less water and energy, we sort our household waste and we prefer to consume products that are produced with less negative human impact. However, when it comes to our own excreta we definitely think of it as waste. And we are glad enough that wastewater treatment syEutrophication or the nutrient enrichment of water bodies, typically by nitrogen and phosphorus has adversely affected the aquatic life and the quality of water. Governments have been forced to take actions in order to reduce the release of these nutrients into the environment. To date the main global effort has been to remove such nutrients at source. However, with an increase in awareness of the

Spatial Statistical Modeling of Insurance Risk An epidemiologist approach to car insurance

Spatial models, such as the Besag, York and Mollie (BYM)model, have long been used in epidemiology and disease mapping. A commonproblem in these subjects is the modelling of number of disease eventsper region; here the BYM models provides a holistic framework for bothcovariates and dependencies between regions.We use these tools to assess the relative insurance risk associated withthe policyholder

Probing Electron Collisions in Nanostructures

This thesis studies the role of interaction between charged particles for transport and optical properties in nanostructures. Simulations are provided for a quantitative description of the system dynamics probed by either current spectroscopy or light absorption. In the first part of the thesis (Part I) the basic theories are described and in the second part of the thesis (Part II) the papers list

New Three-component Landstreamer System Developed for Groundwater and Engineering Applications

A new landstreamer system has been developed that provides high resolution imaging from near surface to medium depths. The system is comprised of a combination three-component array to acquire SH data for near surface and a single component array to acquire typical P-wave data at depth. The first application of the system is being carried out for a groundwater mapping project where detailed knowle

On the Design of Electric Traction Machines : Design and Analysis of an Interior Permanent Magnet Synchronous Machine for Heavy Commercial Vehicles

Recent years have proven the benefits of electrifying the road bound vehicle fleet. With new components entering, the general understanding as well as the components as such needs to be improved. Focus in the thesis is on the design of an electric machine based on specifications of requirements for a commercial heavy vehicle such as a truck or a bus. One strict requirement is that the machine has

Multi-dimensional sinusoidal order estimation using angles between subspaces

Multi-dimensional harmonic retrieval (HR) in white noise is required in numerous applications such as channel estimation in wireless communications and imaging in multiple-input multiple-output radar. In this paper, we propose two R-dimensional (R -D) extensions of the subspace-based MUSIC model order selection scheme, for R≥2R≥2, to detect the number of multi-dimensional cisoids. The key idea in

The musical present: A polyphonic philosophical investigation

How can music education be enriched by the concept of time? This article is based on the assumption that the present moment, the musical ‘now’, is of the utmost importance not only to the musical performer or listener but to the musical learner and teacher as well. It aims at a philosophical discussion and conceptual clarification of a number of issues of time that are considered to be crucial to