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BACKGROUND: Major depressive disorder (MDD) is one of the most common psychiatric disorders and is a great disease burden. However, its underlying pathophysiology and aetiology remain poorly understood. Available evidence suggests that circulating microRNAs (miRNAs) are associated with MDD, but it is still unknown whether miRNAs can predict subsequent incident MDD.METHODS: In this nested case-cont
Phase-noise (PN) estimation and compensation are crucial in millimeter-wave (mmWave) communication systems to achieve high reliability. The PN estimation, however, suffers from high computational complexity due to its fundamental characteristics, such as spectral spreading and fast-varying fluctuations. In this paper, we propose a new framework for low-complexity PN compensation in orthogonal freq
This paper presents an angular-domain massive MIMO detector which exploits sparsity in massive MIMO channel along with a reconfigurable systolic array architecture to achieve high area efficiency. The underlying idea is to perform signal detection in the angular domain, where the channel matrix can have much lower dimension due the limited number of dominant angles (of arrival and departure) of th
Clays can be synthesised to have specific functional properties, which have been exploited in a range of industrial processes. A key characteristic of clay is the presence of a negatively charged surface, surrounded by an oppositely charged rim. Because of that, clays are able to sequester cationic compounds resulting in the formation of ordered layered structures, known as tactoids. Recent resear
Tumors affect the immune system, locally and systemically. The frequencies of specific circulating immune cell populations correlate with disease progression as well as prognosis of the patients. Although largely neglected, conventional antitumoral therapies often possess immunomodulatory properties and affect the levels of specific immune cell populations. Most information, however, derive from a
Stored energies of radiating systems have generated research interest for several decades due to their relationship with Q-factor and fractional bandwidth. In this paper material derivatives are used to provide a new interpretation of widely used stored energy expressions. This provides a fundamental relationship between stored energies of radiating systems and their electromagnetic material prope
The complexity of human tibiofemoral joint motion is now better understood with the advancement of new methodologies to measure tibiofemoral kinematics in vivo. Marker clusters anchored to stainless steel bone pins inserted directly into the femur and tibia provide the most sensitive and accurate means for directly measuring skeletal tibiofemoral joint motion. Despite its invasiveness, this techni
The number of degrees of freedom is a crucial parameter in many electromagnetic problems. In for example modern communication systems spatial diversity is often employed through multiple beams to enhance capacity and reliability. However, while the degrees of freedom can be computed, their connection to physical quantities is not as easily understood. To address this issue, this paper proposes a s
Brain-computer interfaces (BCIs) translate brain activity into digital commands for interaction with the physical world. The technology has great potential in several applied areas, ranging from medical applications to entertainment industry, and creates new conditions for basic research in cognitive neuroscience. The BCIs of today, however, offer only crude online classification of the user's cur
In this paper we propose a shared regression network to jointly estimate the pose of multiple objects, replacing multiple object-specific solutions. We demonstrate that this shared network can outperform other similar approaches that rely on multiple object-specific models by evaluating it on the TLESS dataset using the VSD (Visible Surface Discrepancy). Our approach offers a less complex solution
This paper presents the construction and evaluation of SERP-test, a taxonomy aimed to improve communication between researchers and practitioners in the area of software testing. SERP-test can be utilized for direct communication in industry academia collaborations. It may also facilitate indirect communication between practitioners adopting software engineering research and researchers who are st
A low-latency and area-efficient FFT/IFFT scheme is presented. The main idea is to utilize OFDM guard bands to reduce the operation counts and processing time, which results in 42% latency reduction compared to the reported pipelined schemes. To realize this idea, a modified pipelined architecture and an efficient data scheduling scheme are proposed. Furthermore, the proposed architecture is scala
Empirical software engineering research aims to generate prescriptive knowledge that can help software engineers improve their work and overcome their challenges, but deriving these insights from real-world problems can be challenging. In this paper, we promote design science as an effective way to produce and communicate prescriptive knowledge. We propose using a visual abstract template to commu
Objectives: Among patients who underwent primary surgery for non-small cell lung cancer (NSCLC), recurrent disease is frequent and cannot be accurately predicted solely from TNM stage and histopathological features. The aim of this study was to examine the association of tumor markers in pre-operative serum with recurrent disease. Material and methods: Blood samples were collected prior to lung ca
Planet–planet collisions are a common outcome of instability in systems of transiting planets close to the star, as well as occurring during in-situ formation of such planets from embryos. Previous N-body studies of instability amongst transiting planets have assumed that collisions result in perfect merging. Here, we explore the effects of implementing a more realistic collision prescription on t
Background: Branch-duct intraductal papillary mucinous neoplasm (BD-IPMN) presents a clinical conundrum. Rigorous long-term surveillance or surgical resection is recommended. The economic consequences of the management have not been fully investigated. Methods: A Markov decision model compared 4 strategies for low-risk BD-IPMN: I = upfront total pancreatectomy, II = upfront partial pancreatectomy,
Cloud condensation nuclei (CCN) number concentrations alongside with submicrometer particle number size distributions and particle chemical composition have been measured at atmospheric observatories of the Aerosols, Clouds, and Trace gases Research InfraStructure (ACTRIS) as well as other international sites over multiple years. Here, harmonized data records from 11 observatories are summarized,
We study how close-in systems such as those detected by Kepler are affected by the dynamics of bodies in the outer system. We consider two scenarios: outer systems of giant planets potentially unstable to planet-planet scattering and wide binaries that may be capable of driving Kozai or other secular variations of outer planets' eccentricities. Dynamical excitation of planets in the outer system r
In 1822 the Parliament of the United Kingdom passed The Cruel Treatment of Cattle Act, which today is considered to be an important forerunner to modern animal protection and anti-cruelty legislation. However, the new Enlightenment attitudes to animals stemmed from an overly anthropocentric perception of the natural world and the place of the human animal in it. At the heart of the movement agains
