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Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease.

Recent studies in animal models of Parkinson's disease (PD) have provided evidence that dopamine released from spared serotonin afferents can act as a trigger of dyskinetic movements induced by repetitive, low doses of levodopa. Serotonin neurons have the capacity to store and release dopamine synthesized from systemically administered levodopa. However, because of the lack of any autoregulatory f

Efficient Order Batching Optimization Using Seed Heuristics and the Metropolis Algorithm

Order Picking in warehouses is often optimized using a method known as Order Batching, which means that one vehicle can be assigned to pick a batch of several orders at a time. There exists a rich body of research on Order Batching Problem (OBP) optimization, but one area which demands more attention is computational efficiency, especially for optimization scenarios where warehouses have unconvent

The Gaia -ESO survey : The non-universality of the age-chemical-clocks-metallicity relations in the Galactic disc

Context. In the era of large spectroscopic surveys, massive databases of high-quality spectra coupled with the products of the Gaia satellite provide tools to outline a new picture of our Galaxy. In this framework, an important piece of information is provided by our ability to infer stellar ages, and consequently to sketch a Galactic timeline. Aims. We aim to provide empirical relations between s

Stillbirth or neonatal death before 45 post-menstrual weeks in relation to gestational duration in pregnancies at 39 weeks of gestation or beyond : the impact of parity and body mass index. A national cohort study

Objective: To investigate the risk of stillbirth or neonatal death before 45 post-menstrual weeks in relation to gestational duration, stratified by body mass index (BMI) and parity. Design: Retrospective study. Setting: Data from the Swedish Medical Birth Register. Population: Singleton, cephalic births at between 39+0 and 42+2 weeks of gestation, 2005–2016 (n = 892 339). Methods: Relative risk r

Informationssokning2016

Brevmall Att söka vetenskapliga artiklar – En vägledning i systematisk litteratursökning November 2008 Uppdaterad 2016-01-14 Monica Landén Medicinska fakultetens bibliotek Lund Medicinska fakultetens bibliotek Lunds universitet, Box 157, 221 00 LUND 1 1 1 ................................................................................................................................................

https://www.medicin.lu.se/sites/medicin.lu.se/files/informationssokning2016.pdf - 2026-05-27

Prognostic performance of preoperative cardiac troponin and perioperative changes in cardiac troponin for the prediction of major adverse cardiac events and mortality in noncardiac surgery : A systematic review and meta-analysis

Background Increased postoperative cardiac troponin (cTn) independently predicts short-term mortality. Previous studies suggest that preoperative cTn also predicts major adverse cardiovascular events (MACE) and mortality after noncardiac surgery. The value of preoperative and perioperative changes in cTn as a prognostic tool for adverse outcomes has been sparsely investigated. Methods and findings

Formation of moon systems around giant planets : Capture and ablation of planetesimals as foundation for a pebble accretion scenario

The four major satellites of Jupiter, known as the Galilean moons, and Saturn's most massive satellite, Titan, are believed to have formed in a predominantly gaseous circum-planetary disk during the last stages of formation of their parent planet. Pebbles from the protoplanetary disk are blocked from flowing into the circumplanetary disk by the positive pressure gradient at the outer edge of the p

The Gaia -ESO Survey : Spectroscopic-asteroseismic analysis of K2 stars in Gaia -ESO

Context. The extensive stellar spectroscopic datasets that are available for studies in Galactic Archeaology thanks to, for example, the Gaia-ESO Survey, now benefit from having a significant number of targets that overlap with asteroseismology projects such as Kepler, K2, and CoRoT. Combining the measurements from spectroscopy and asteroseismology allows us to attain greater accuracy with regard

Multi Cylinder Partially Premixed Combustion Performance Using Commercial Light-Duty Engine Hardware

This work investigates the performance potential of an engine running with partially premixed combustion (PPC) using commercial diesel engine hardware. The engine was a 2.01 SAAB (GM) VGT turbocharged diesel engine and three different fuels were run - RON 70 gasoline, RON 95 Gasoline and MK1 diesel. With the standard hardware an operating range for PPC from idle at 1000 rpm up to a peak load of 10

Seven elements for capacity development for disaster risk reduction

Capacity development for disaster risk reduction is an important process to substantially reduce disaster losses, which threaten sustainable development and the achievement of the Millennium Development Goals. This paper presents a theoretical framework with seven elements for capacity development for disaster risk reduction that has been tested in practise with noteworthy results. The seven eleme

Cation-Dependent Hot Carrier Cooling in Halide Perovskite Nanocrystals

Lead halide perovskites (LHPs) nanocrystals (NCs), owing to their outstanding photophysical properties, have recently emerged as a promising material not only for solar cells but also for lighting and display applications. The photophysical properties of these materials can be further improved by chemical engineering such as cation exchange. Hot carrier (HC) cooling, as one of the key photophysic

Growth after the streaming instability. From planetesimal accretion to pebble accretion

Context. Streaming instability is a key mechanism in planet formation, clustering pebbles into planetesimals with the help of self-gravity. It is triggered at a particular disk location where the local volume density of solids exceeds that of the gas. After their formation, planetesimals can grow into protoplanets by feeding from other planetesimals in the birth ring as well as by accreting inward

Slow-light-based optical frequency shifter

We demonstrate experimentally and theoretically a controllable way of shifting the frequency of an optical pulse by using a combination of spectral hole burning, slow light effect, and linear Stark effect in a rare-earth-ion-doped crystal. We claim that the solid angle of acceptance of a frequency shift structure can be close to 2π, which means that the frequency shifter could work not only for op

Discretized multi-level elution trajectory: A proof-of-concept demonstration

Biomolecular and pharmaceutical downstream processing is dominated by chromatographic separation, which is associated with high product quality, low capacity and high costs. The separation can be optimized to minimize the costs while achieving a high purity. This paper presents an experimental validation of a discretized multi-level elution (DiME) trajectory, implemented on commercially available

Male Experiences of Life After Recovery From an Eating Disorder

The aim of this study was to describe how former male patients perceive life after recovery from an eating disorder. A qualitative method with a phenomenographic approach was used to identify ways of experiencing recovery. Two descriptive categories were developed: body acceptance and self-worth. Six conceptions describe how recovered patients now relate in a balanced way to exercise and food, usi

Control-over-the-cloud: A performance study for cloud-native, critical control systems

In the Industry 4.0 era, time-sensitive and missioncritical control applications still have a long way to go, from being tied down and co-located with the systems they control, to taking full advantage of the cloud. Conservatively keeping applications local will deprive these complex applications of abundantcompute capacity, wider system integration, and the potential for collaborative control eff