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11/12/2023, 13:59 Nya behandlingar för tidigare ”omöjliga” sjukdomar - DN.se https://www.dn.se/varlden/nya-behandlingar-for-sjukdomar-som-tidigare-var-omojliga-att-bota/ 1/8 En utskrift från Dagens Nyheter, 2023-12-11 12:56 Artikelns ursprungsadress: https://www.dn.se/varlden/nya-behandlingar-for-sjukdomar-som-tidigare-var-omojliga-att-bota/ VÄRLDEN Nya behandlingar för sjukdomar som tidigare var
Background: Subgroups of adult-onset diabetes, namely severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), and mild obesity-related diabetes (MOD) or mild age-related (MARD) diabetes, have been defined with clinical variables and a machine-learning approach. Our aim was to describe their long-term outcomes and mortality. Methods: In
Erythroid cell commitment and differentiation proceed through activation of a lineage-restricted transcriptional network orchestrated by a group of well characterized genes. However, the minimal set of factors necessary for instructing red blood cell (RBC) development remains undefined. We employed a screen for transcription factors allowing direct lineage reprograming from fibroblasts to induced
After a long career in studying agricultural and rural development, in the following paper I take the opportunity to reflect on these issues in the rear view mirror. The advantage of this is of course that my biographical time span now covers a considerable historical one, starting with the apocalyptic alarms over the population bomb at the end of the 60s, especially in Asia, and the widespread fe
Background: Right ventricular (RV) systolic function is an important determinant of outcome in patients with pulmonary hypertension (PH). Conventional echocardiographic measures of RV are mainly based on longitudinal contractility. Recently, measurement of RV global longitudinal strain derived from multiple windows (RVGLS) has emerged as an option but has not been well evaluated. The aim of the pr
Transition-metal complexes are used as photosensitizers1, in light-emitting diodes, for biosensing and in photocatalysis2. A key feature in these applications is excitation from the ground state to a charge-transfer state3,4; the long charge-transfer-state lifetimes typical for complexes of ruthenium5 and other precious metals are often essential to ensure high performance. There is much interest
Den 13 november 1872 inträffade en extrem översvämning i kustområdena kring Södra Östersjön. Högt vattenstånd i kombination med höga vågor ledde till att cirka 300 personer omkom och fler än 15 000 blev hemlösa. Utmed Skånes kust omkom minst 23 personer, över 100 bostadshus förstördes och hundratals kustfiskare förlorade sin inkomstkälla då båtar och fiskeredskap slogs sönder och drogs ut i havet.On November 13, 1872 an extreme flood occurred in the coastal areas surrounding the South Baltic Sea. An extreme storm surge in combination with high waves caused the death of about 300 people and more than 15,000 people lost their homes. Along the coast of Scania, southern Sweden, at least 23 people were killed and more than 100 houses were destroyed. Hundreds of fishermen lost their source of in
Enumeration of circulating tumor cells (CTCs) predicts overall survival and treatment response in metastatic cancer, but as many commercialized assays isolate CTCs positive for epithelial cell markers alone, CTCs with little or no epithelial cell adhesion molecule (EpCAM) expression stay undetected. Therefore, CTC enrichment and isolation by label-free methods based on biophysical rather than bioc
Internationalisation of higher education is a current theme in research and politics of higher education. The theme in this paper is related to present developments and concerns of the growing border-crossing activities that take place between nations and their systems of Higher Education. Higher education is expected to be based on research, research to be an international activity, and the unive
A low-weight aerosol sampler has been developed and tested. Internal losses for both sub-micron and large particles ( < 10 tam) are of the order of 5 %. The size fractionation patterns indicate that the sampler may be used to collect a separate respirable fraction in good agreement with the BMRC standard and a coarse fraction deternuned by the inlet design.
Med en elektrifiering av tunga lastbilar kommer elbehovet att ̈oka kraftigt och elnätet ̈ar inte förberedd p ̊a utmaningen. Det rader kapacitetsbrist i nätet och det behöver utredas hur den kan undvikas. Transportsektorn star infor stora förändringar för att minska sitt klimatavtyck. Elnätet ̈ar en kritisk infrastruktur för att möjliggöra denna omställning. Förutom att bygga ut finns det m ̈ojlighThe transport sector is facing major challenges to reduce the greenhouse gas emissions. The electrification of the freight fleet, which is an important step towards emission reduction, will result in capacity challenges in the grid. The aim of this thesis is to evaluate how the existing grid is affected by the electrification of heavy trucks and what solutions or reinforcements needs to be impleme
Boilerplate är en term som används för att beskriva standardiserade klausuler som ofta återfinns i slutet av ett avtal och som behandlar generella frågor som inte är beroende av avtalets art eller omfattning. Det finns flertalet olika boilerplate, varav en är integrationsklausulen. Klausulen har i och med internationaliseringen av den kommersiella rätten blivit mycket vanligt förekommande i svenskBoilerplate is a term used to describe standardized clauses that often appear at the end of a contract and deals with general issues that are not dependent on the nature or scope of the agreement. There are several different boilerplates, one of which is the entire agreement clause. The entire agreement clause has become very common in Swedish law due to the internationalization of Swedish busines
