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Biological diversity encompasses the genetic diversity within each species, the range of species in a given ecosystem e.g. species diversity and the diversity of ecosystems across an entire region (Primack, 2000). At present 1 per cent of the world’s described species are threatened with extinction. The most pervasive and overriding threat is habitat loss and degradation due to human activity such

In the study of motor systems it is often necessary to track the movements of an experimental animal in great detail to allow for interpretation of recorded brain signals corresponding to different control signals. This task becomes increasingly difficult when analyzing complex compound movements in freely moving animals. One example of a complex motor behavior that can be studied in rodents is th

Since I finished my PhD thesis in June 2014, I have lived a stimulating but also somewhat precarious life at Lund University. It is no secret that permanent teaching positions are hard to come by, and during the time I have been teaching as temporary staff on a number of different courses, I have started to consider what the lack of permanent positions means for the pedagogical work carried out at

Aim: We studied the impact of maternal and pregnancy-related conditions and the effect of gestational age itself, on the health of infants born late preterm. Methods: Singletons born in gestational weeks 34 + 0 to 41 + 6 in 1995–2013 in the southern region of Sweden were identified from a perinatal register. We found 14 030 infants born late preterm and 294 814 born at term. A hierarchical system

The blood flow in rat liver was measured with Xe-133. Three techniques for administering the activity to the liver were employed: injection via the portal vein, via the hepatic artery, and directly into the liver parenchyma. Use of intraparenchymal injection of Xe-133 gave 60% higher flow values than by portal or arterial injection techniques. Mean flow index (k1) was for portal injection 0.52, fo

Background: Selection and selection bias are terms that lack consistent definitions and have varying meaning and usage across disciplines. There is also confusion in current definitions between underlying mechanisms that lead to selection and their consequences. Consequences of selection on study validity must be judged on a case-by-case basis depending on research question, study design and analy

The article analyses the role of the historical dimension in official Swedish debate, with a focus on the Swedish government's Living History information project on the Holocaust

Students working in groups is a commonly used method of instruction in higher education, popularized by the introduction of problem based learning. As a result, management of small groups of people has become an important skill for teachers. The objective of our study is to investigate why conflicts arise in student groups at the Faculty of Engineering at Lund University and how teachers manage th

Magnetic resonance spectroscopy (MRS) is a non-invasive technique that can be used to detect and quantify multiple metabolites. This chapter will review some of the applications of MRS to the study of brain functions. Typically, (1)H-MRS can detect metabolites reflecting neuronal density and integrity, markers of energy metabolism or inflammation, as well as neurotransmitters. The complexity of th

Huntington disease (HD) is a fatal neurodegenerative disorder caused by an expanded CAG repeat. Its length can be used to estimate the time of clinical diagnosis, which is defined by overt motor symptoms. Non-motor symptoms begin before motor onset, and involve changes in hypothalamus-regulated functions such as sleep, emotion and metabolism. Therefore we hypothesized that hypothalamic changes occ

Objective: To investigate whether inverse probability of participation weighting (IPPW) using register data on sociodemographic and disease history variables can improve external validity in a cohort study with selective participation. Study Design and Setting: We fitted various IPPW models by logistic regression using register data for the participants (n = 1,111) and nonparticipants (n = 1,132)

Recurrent use of the Housing Enabler instrument has highlighted methodological challenges of broader scientific interest, namely interactions between personal functional capacity (P) and exposures to features (here potential barriers) in the built housing environment (E). This study aimed to propose and illustrate an analytic approach, separating P × E interaction effects (here accessibility probl

The impact of systemic 27-hydroxycholesterol (27HC) and intratumoral CYP27A1 expression on pathobiology and clinical response to statins in breast cancer needs clarification. 27HC is an oxysterol produced from cholesterol by the monooxygenase CYP27A1, which regulates intracellular cholesterol homeostasis. 27HC also acts as an endogenous selective estrogen receptor (ER) modulator capable of increas