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How people wake up is associated with previous night’s sleep together with physical activity and food intake

How people wake up and regain alertness in the hours after sleep is related to how they are sleeping, eating, and exercising. Here, in a prospective longitudinal study of 833 twins and genetically unrelated adults, we demonstrate that how effectively an individual awakens in the hours following sleep is not associated with their genetics, but instead, four independent factors: sleep quantity/quali

Graceful degradation to prolong lifetime of semiconductors

Sustainability footprints are caused by semiconductor malfunctioning; production challenges (low yield) and customer returns (wear-out). We work with standards, techniques, and methods to quickly and accurately pin-point and mitigate malfunctioning aiming at graceful degradation to prolong operational lifetime.

Learning curve for robot-assisted laparoscopic radical prostatectomy in a large prospective multicentre study

Objective: Differences in outcome after radical prostatectomy for prostate cancer can partly be explained by intersurgeon differences, where degree of experience is one important aspect. This study aims to define the learning curve of robot-assisted laparoscopic prostatectomy (RALP) regarding oncological and functional outcomes. Materials and methods: Out of 4003 enrolled patients in the LAPPRO tr

Info stu 20min

Studieverkstaden Individuell handledning, kurser, föreläsningar Via mejl: studieverkstad@stu.lu.se Via telefon: 046-222 43 92 Läs mer på vår hemsida: www.lu.se/studieverkstad Studieverkstaden Boka en tid! Presentatör Presentationsanteckningar Om du någon gång under kursen skulle vilja prata med någon om akademiskt skrivande, studieteknik eller muntliga presentationer – boka en tid hos Studieverkst

https://www.psy.lu.se/sites/psy.lu.se/files/info_stu_20min.pdf - 2026-05-20

Convergent input to the main output neurons of the decision making center of a bee brain

Centret för navigation i hjärnan hos ett bi I hjärnan hos ett litet bi som kallas Megalopta genalis finns en del som utgör centret för bland annat navigation. Detta navigationscenter benämns det centrala komplexet och ligger bakom de sofistikerade sätt som denna lilla organism förflyttar sig på i sin omvärld. Det har forskats på det centrala komplexet under flera år och nyligen kartlade några for

Will the electrical grid sustain the change towards an electrified freight truck fleet?

Med en elektrifiering av tunga lastbilar kommer elbehovet att ̈oka kraftigt och elnätet ̈ar inte förberedd p ̊a utmaningen. Det rader kapacitetsbrist i nätet och det behöver utredas hur den kan undvikas. Transportsektorn star infor stora förändringar för att minska sitt klimatavtyck. Elnätet ̈ar en kritisk infrastruktur för att möjliggöra denna omställning. Förutom att bygga ut finns det m ̈ojlighThe transport sector is facing major challenges to reduce the greenhouse gas emissions. The electrification of the freight fleet, which is an important step towards emission reduction, will result in capacity challenges in the grid. The aim of this thesis is to evaluate how the existing grid is affected by the electrification of heavy trucks and what solutions or reinforcements needs to be impleme

Does co-development with ai assistants lead to more maintainable code? : A registered report

[Background/Context] AI assistants like GitHub Copilot are transforming software engineering; several studies have highlighted productivity improvements. However, their impact on code quality, particularly in terms of maintainability, requires further investigation. [Objective/Aim] This study aims to examine the influence of AI assistants on software maintainability, specifically assessing how the

SPARC : The Standardised Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography Analysis and Reporting Consensus: A Delphi Analysis

Background and objective: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is an evolving diagnostic tool for prostate cancer. There is a need to harmonise existing guidelines and reporting recommendations for PSMA PET/CT. The Standardised PSMA PET/CT Analysis and Reporting Consensus (SPARC) project aims to consolidate classifications and recommen

SPL-BEV: Soccer Player Localization and Birds-Eye-View Estimation

In this work we present SPL-BEV, a method to localize soccer players on a pitch from a monocular RGB camera. SPL-BEV features a network with few parameters that does not need to make any explicit object detection before localization is made. With SPL-BEV we show increased performance on the Spiideo SoccerNet SynLoc dataset compared to the best provided baseline result. The SPL-BEV system samples f

Treatment Trajectories in Metastatic Hormone-sensitive Prostate Cancer : A PIONEER+ Big Data Analysis

BACKGROUND AND OBJECTIVE: The treatment landscape for metastatic hormone-sensitive prostate cancer (mHSPC) is evolving rapidly. Real-world data (RWD) are essential to understand actual treatment use and outcomes. This study aimed to describe treatment trajectories and clinical outcomes in a large, multicenter RWD cohort under the PIONEER project. METHODS: Eight European and US databases (2016-2020

Self-adaptive ZrN coating enables stable acidic oxygen evolution on Co3O4through dynamic surface reconstruction

The development of acid-stable, non-precious catalysts for the oxygen evolution reaction (OER) remains a critical challenge for proton exchange membrane water electrolyzers (PEMWEs). While Co3O4 shows promising OER activity, its rapid dissolution in acidic media severely limits practical application. Here, we design a self-adaptive protection strategy by depositing ZrN coatings on Co3O4 precursor

RAB3GAP2 is a regulator of skeletal muscle endothelial cell proliferation and associated with capillary-to-fiber ratio

Skeletal muscle capillary density is correlated with physical performance and whole-body metabolic properties. Thus, we performed a genome-wide association study of skeletal muscle capillary-to-fiber ratio (C:F) (n = 603 males) and found that the rs115660502 G allele was associated (p < 5 × 10 -8) with increased C:F and reduced skeletal muscle expression of RAB3 GTPase-activating non-catalytic pr

Bridging the gap in heart failure management : the effect of a cross-disciplinary intervention on guidelines-directed medical therapy in primary care

BACKGROUND AND AIMS: Guideline-directed medical therapy (GDMT) for heart failure (HF) is underutilized in primary care, particularly among older adults with chronic stable HF. This prospective quality improvement study, Heart Failure in Southern Sweden (HISS), evaluated the impact of a cross-disciplinary implementation project combining cardiology and primary care expertise to enhance GDMT adheren

Autoimmunity to selenoprotein P predicts breast cancer recurrence

BackgroundLow concentrations of serum selenium (Se) and its main transporter selenoprotein P (SELENOP) are associated with a poor prognosis following breast cancer diagnosis. Recently, natural autoantibodies (aAb) with antagonistic properties to SELENOP uptake have been identified in healthy subjects, and in patients with thyroid disease. Given the potential transport disrupting properties, we hyp

Reusing IEEE 1687-Compatible Instruments and Sub-Networks over a System Bus

Accessing embedded test and monitoring circuitry (the so-called embedded instruments) in in-field products can reduce maintenance and diagnostics costs. Performing such access can be facilitated when done over an internal system bus, due to that it might be faster and less cumbersome to reach a system processor (on an in-field product) over a network interface, compared with the effort and speed o

Polygenic scores, diet quality, and type 2 diabetes risk : An observational study among 35,759 adults from 3 US cohorts

Background Bothgenetic and lifestyle factors contribute to the risk of type 2 diabetes, but the extent to which there is a synergistic effect of the 2 factors is unclear. The aim of this study was to examine the joint associations of genetic risk and diet quality with incident type 2 diabetes. Methods and findings We analyzed data from 35,759 men and women in the United States participating in the

Estimating the Direct Effect between Dietary Macronutrients and Cardiometabolic Disease, Accounting for Mediation by Adiposity and Physical Activity

Assessing the causal effects of individual dietary macronutrients and cardiometabolic disease is challenging owing to the complexity to distinguish direct effects from those mediated or confounded by other factors. To estimate these effects, intake of protein, carbohydrate, sugar, fat, and its subtypes were obtained using food frequency data derived from a Swedish population-based cohort (n~60,000

Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

The presentation and underlying pathophysiology of type 2 diabetes (T2D) is complex and heterogeneous. Recent studies attempted to stratify T2D into distinct subgroups using data-driven approaches, but their clinical utility may be limited if categorical representations of complex phenotypes are suboptimal. We apply a soft-clustering (archetype) method to characterize newly diagnosed T2D based on

Exposome-wide ranking of modifiable risk factors for cardiometabolic disease traits

The present study assessed the temporal associations of ~ 300 lifestyle exposures with nine cardiometabolic traits to identify exposures/exposure groups that might inform lifestyle interventions for the reduction of cardiometabolic disease risk. The analyses were undertaken in a longitudinal sample comprising > 31,000 adults living in northern Sweden. Linear mixed models were used to assess the av