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Popular Abstract in Swedish Vävnadskallikrein (VK) är ett äggvitespjälkande protein som dels kan aktivera vävnadsnedbrytande enzymer som kollagenas och gelatinas och dels spjälkar kininogen till kininer (bradykinin och kallidin). Via bindning till speciella kininreceptorer (B2 receptorer) som finns överallt i kroppen, styr kininerna olika processer i de flesta av kroppens organ och vävnader såsom Tissue kallikrein releases pharmacollogically highly active kinins from kininogen. Many other enzymes may also release kinins. The aim of the study was to clarify the pathophysiological role of tissue kallikrein in acute pancreatitis. Two sensitive and specific radioimmunoassays for porcine and human tissue kallikrein were developed. A large release of tissue kallikrein from the pancreatic gland

The state of the farming industry in Europe has been put under the spotlight in recent years due to a number of different food scares and disease outbreaks. Many new quality assurance schemes have been formed to accompany the existing environmental monitoring schemes, to give concerned consumers some guarantee when buying food that it is of a good quality and the environmental load of production h

BACKGROUND AND OBJECTIVES: The treatment of acquired aplastic anemia (AA) is based on allogeneic bone marrow transplantation (BMT) and immunosuppressive therapy. The aim of this study was to assess the outcome of children and adults with AA treated in the last decade, and to determine whether results have improved in two sequential time periods,1991-1996 and 1997-2002. DESIGN AND METHODS: Two-thou

Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study ARTICLE Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study Markus Mattila1,2 & Iris Erlund2,3 & Hye-Seung Lee4 & Sari Niinistö2 & Ulla Uusitalo4 & Carin Andrén Aronsson5 & Sandra Hummel6,7,8 & Hemang Parikh4 & Stephen S. Rich9 & William Hagopian10 & Jorma Toppari11

https://www.teddy.lu.se/sites/teddy.lu.se/files/plasma_ascorbic_acid_and_the_risk_of_islet_autoimmunity_and_type_1_diabetes._pdf.pdf - 2026-05-19

Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy Pediatric Diabetes 2016: 17(Suppl. 22): 65–72 doi: 10.1111/pedi.12390 All rights reserved © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. Pediatric Diabetes Review Article Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy Lernmark Å. Environmental facto

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/59%2011042016_679_59_REVIEW_Lernmark_PedDiab_2016.pdf - 2026-05-19

Genetic mapping of complement system proteins for islet autoimmunity in children with high risk of T1D communications biology Article A Nature Portfolio journal https://doi.org/10.1038/s42003-025-08739-9 Genetic mapping of complement system proteins for islet autoimmunity in children with high risk of T1D Check for updates Xiaowei Hu 1 , Bobbie-Jo M. Webb-Robertson 2,3, Hemang M. Parikh4, Ernesto

https://www.teddy.lu.se/sites/teddy.lu.se/files/2025-12/177%20Hu%20et%20al.%20Complement%20Communications%20biology%202025%20(1).pdf - 2026-05-19

Quantitative investigation of insect activity in their natural habitat is a challenging task for entomologist. It is difficult to address questions such as flight direction, predation strength and overall activities using the current techniques such as traps and sweep nets. A multi-spectral kHz remote detection system using sunlight as an illumination source is presented. We explore possibilities

Background: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not i

Accountability is central for accelerating progress towards achieving the Sustainable Development Goals (SDGs). It means to hold powerful actors answerable for how they turn agreements into action. Governments, who hold the main responsibility for SDG implementation, can in the ideal case be held accountable by voters, parliaments, civil society, and the media, for how they address the SDGs. At th

Disorder is an intrinsic feature of all solids, from crystals of atoms to superlattices of colloidal nanoparticles. Unlike atomic crystals, in nanocrystal superlattices, a single misplaced particle can affect the positions of neighbors over long distances, leading to cumulative disorder. This elusive form of collective particle displacement leaves clear signatures in diffraction, but little i

This study examined whether immersive virtual reality (VR) supports second-language vocabulary learning in school-aged children compared to passive computer-based training. Seventy-three Swedish middle-school students learned novel words by assembling objects in VR and by viewing object assembly on a computer screen in a crossover design. Word recall was tested after each condition, and individual

Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants remain inadequately understood. In this study, we report a genome-wide association study of HF and its subtypes in a sample of 1.9 million individuals. A total of 153,174 individual

Astrocytes play a crucial role in the onset and progression of amyotrophic lateral sclerosis (ALS), a fatal disorder marked by the degeneration of motor neurons (MNs) in the central nervous system. Although astrocytes in ALS are known to be toxic to MNs, the pathological changes leading to their neurotoxic phenotype remain poorly understood. In this study, we generated human astrocytes from induce

Mellan metastas och primärtumör – karaktärisering av cirkulerande tumörceller Bröstcancer är idag en av de vanligaste och den typ av cancer som leder till näst flest dödsfall bland kvinnor idag. Det uppskattas att ungefär 30% av alla som lider av primär bröstcancer till slut utvecklar metastatisk bröstcancer (MBC), detta betyder att cancer spridit sig till andra delar av kroppen. MBC går idag inBackground: Breast cancer is the second most common cause of cancer related death among women in the developed world. Around 30% of patients diagnosed with primary breast cancer will develop metastatic breast cancer. It is believed that the tumor cells found in the blood, termed Circulating tumor cells (CTCs), could serve as a prognostic marker for this disease as it progresses. Objectives: To st