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Subsequent leukaemia in autoimmune disease patients.

Previous studies have shown that patients diagnosed with some autoimmune (AI) diseases are at an increased risk of leukaemia but limited data are available on survival. We systematically analysed the risks (standardized incidence ratio, SIR) and survival (hazard ratio, HR) in nine types of leukaemia among 402 462 patients hospitalized for any of 33 AI diseases and compared to persons not hospitali

Decrease in the incidence of total hip arthroplasties in patients with rheumatoid arthritis - results from a well defined population in south Sweden

Introduction: One aim of modern pharmacologic treatment in rheumatoid arthritis (RA) is to prevent joint destruction and reduce the need for surgery. Our purpose was to investigate secular trends in the incidence of primary total hip and knee arthroplasties in a well defined sample of patients with RA. Methods: Prevalent cases with RA in 1997 and incident cases from 1997 to 2007 in a community bas

Mindfulness group therapy in primary care patients with depression, anxiety and stress and adjustment disorders: randomised controlled trial.

Background Individual-based cognitive-behavioural therapy (CBT) is in short supply and expensive. Aims The aim of this randomised controlled trial (RCT) was to compare mindfulness-based group therapy with treatment as usual (primarily individual-based CBT) in primary care patients with depressive, anxiety or stress and adjustment disorders. Method This 8-week RCT (ClinicalTrials.gov ID: NCT0147637

Depression, neighborhood deprivation and risk of type 2 diabetes

Neighborhood characteristics have been associated with both depression and diabetes, but to date little attention has been paid to whether the association between depression and diabetes varies across different types of neighborhoods. This prospective study examined the relationship between depression, neighborhood deprivation, and risk of type 2 diabetes among 336,340 adults from a national-repre

Law, Norms, Piracy and Online Anonymity – Practices of de-identification in the global file sharing community

Purpose The purpose of this study is to better understand online anonymity in the global file-sharing community in the context of social norms and copyright law. The study describes the respondents in terms of use of Virtual Private Networks (VPNs) or similar services with respect to age, gender, geographical location, as well as analysing the correlation with file-sharing frequencies. Design/me

Walkability parameters, active transportation and objective physical activity: moderating and mediating effects of motor vehicle ownership in a cross-sectional study

Background: Neighborhood walkability has been associated with physical activity in several studies. However, as environmental correlates of physical activity may be context specific, walkability parameters need to be investigated separately in various countries and contexts. Furthermore, the mechanisms by which walkability affects physical activity have been less investigated. Based on previous re

Bone Status in Professional Cyclists

Professional cycling combines extensive endurance training with non weight-bearing exercise, two factors often associated with lower bone mineral density (BMD). Therefore BMD was measured with dual-energy x-ray absorptiometry in 30 professional road cyclists (mean (SD) age: 29.1 (3.4) years; height: 178.5 (6.7) cm; weight: 71.3 (6.1) kg; %fat mass: 9.7 (3.2)%; (V) over dotO(2) max: 70.5 (5.5) ml .

The Digital IP Challenge Revisited – File-sharing and Copyright Development in Hungary

The emphasis here is the need to understand both the normative gap and the role of digital architecture in order to display the inherent challenge that copyright meets in a digital society. Consequently, in being a descriptively focused study, this article studies contemporary Hungarian copyright and contrasts this to the findings from a survey with over 500 respondents from the Hungarian file-sha

Online Piracy, Anonymity and Social Change – Deviance Through Innovation

This article analyses current trends in the use of anonymity services among younger Swedes (15-25) and focuses on individuals engaging in illegal file sharing in order to better understand the rationale behind both file sharing as well as online anonymity, especially in relation to enforcement of copyright. By comparing the findings of a survey conducted on three different occasions (early 2009, l

Efficient methods of nanoimprint stamp cleaning based on imprint self-cleaning effect.

Nanoimprint lithography (NIL) is a nonconventional lithographic technique that promises low-cost, high-throughput patterning of structures with sub-10 nm resolution. Contamination of nanoimprint stamps is one of the key obstacles to industrialize the NIL technology. Here, we report two efficient approaches for removal of typical contamination of particles and residual resist from stamps: thermal a

Venous Thromboembolism Does Not Share Strong Familial Susceptibility with Ischemic Stroke: A Nationwide Family Study in Sweden.

BACKGROUND: -Coagulation allelic variants associated with venous thromboembolism (VTE) have been suggested to be involved in the pathogenesis of ischemic stroke. This nationwide study aimed at determining whether VTE shares familial susceptibility with ischemic stroke. Method and Results-The Swedish Multigeneration Register of 0-75-year-old subjects was linked to the Swedish Hospital Discharge Reg

Injury and illness epidemiology in elite athletes during the Olympic, Youth Olympic and Paralympic Games: a systematic review and meta-analysis

Objective To systematically review and synthesise the incidence and characteristics of injuries and illnesses among athletes participating in the Olympic, Youth Olympic and Paralympic Games.Design Systematic review and meta-analysis.Data sources PubMed, Embase, CINAHL, Scopus and Web of Science were searched up to 2 July 2024, and Google Scholar, ClinicalTrials.gov and WHO International Clinical T

Data-Driven Cluster Analysis of Cerebrospinal Fluid Proteome and Associations with Clinical Phenotypes in Systemic Lupus Erythematosus

OBJECTIVE: To explore the cerebrospinal fluid (CSF) proteome in systemic lupus erythematosus (SLE) and the associations between the CSF proteomic patterns and clinical manifestations.METHODS: CSF samples from 29 female outpatients with SLE were analyzed with label-free liquid chromatography tandem mass spectrometry. Inclusion and CSF collection were conducted irrespective of clinical manifestation

Professionalization, Gender and Anonymity in the Global File Sharing Community

This article presents the analysis of a large survey on file-sharing that was conducted in April 2011 with over 75,000 respondents from all over the world. The study, also known as The Research Bay, due to that it was conducted in collaboration with the infamous BitTorrent site The Pirate Bay, by the Cybernorms research group. The aim of the online study of The Pirate Bay community has been to des